Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis

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Standard

Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis. / Mittal, Anuradha; Pachter, Lior; Nelson, J. Lee; Kjærgaard, Hanne; Smed, Mette Kiel; Gildengorin, Virginia L.; Zoffmann, Vibeke; Hetland, Merete Lund; Jewell, Nicholas P.; Olsen, Jorn; Jawaheer, Damini.

I: PLOS ONE, Bind 10, Nr. 12, e0145204, 18.12.2015, s. 1-15.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Mittal, A, Pachter, L, Nelson, JL, Kjærgaard, H, Smed, MK, Gildengorin, VL, Zoffmann, V, Hetland, ML, Jewell, NP, Olsen, J & Jawaheer, D 2015, 'Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis', PLOS ONE, bind 10, nr. 12, e0145204, s. 1-15. https://doi.org/10.1371/journal.pone.0145204

APA

Mittal, A., Pachter, L., Nelson, J. L., Kjærgaard, H., Smed, M. K., Gildengorin, V. L., Zoffmann, V., Hetland, M. L., Jewell, N. P., Olsen, J., & Jawaheer, D. (2015). Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis. PLOS ONE, 10(12), 1-15. [e0145204]. https://doi.org/10.1371/journal.pone.0145204

Vancouver

Mittal A, Pachter L, Nelson JL, Kjærgaard H, Smed MK, Gildengorin VL o.a. Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis. PLOS ONE. 2015 dec. 18;10(12):1-15. e0145204. https://doi.org/10.1371/journal.pone.0145204

Author

Mittal, Anuradha ; Pachter, Lior ; Nelson, J. Lee ; Kjærgaard, Hanne ; Smed, Mette Kiel ; Gildengorin, Virginia L. ; Zoffmann, Vibeke ; Hetland, Merete Lund ; Jewell, Nicholas P. ; Olsen, Jorn ; Jawaheer, Damini. / Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis. I: PLOS ONE. 2015 ; Bind 10, Nr. 12. s. 1-15.

Bibtex

@article{6bc4b48c99d2468394f72aeac2e997ff,
title = "Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis",
abstract = "Background Pregnancy induces drastic biological changes systemically, and has a beneficial effect on some autoimmune conditions such as rheumatoid arthritis (RA). However, specific systemic changes that occur as a result of pregnancy have not been thoroughly examined in healthy women or women with RA. The goal of this study was to identify genes with expression patterns associated with pregnancy, compared to pre-pregnancy as baseline and determine whether those associations are modified by presence of RA. Results In our RNA sequencing (RNA-seq) dataset from 5 healthy women and 20 women with RA, normalized expression levels of 4,710 genes were significantly associated with pregnancy status (pre-pregnancy, first, second and third trimesters) over time, irrespective of presence of RA (False Discovery Rate (FDR)-Adjusted p value",
author = "Anuradha Mittal and Lior Pachter and Nelson, {J. Lee} and Hanne Kj{\ae}rgaard and Smed, {Mette Kiel} and Gildengorin, {Virginia L.} and Vibeke Zoffmann and Hetland, {Merete Lund} and Jewell, {Nicholas P.} and Jorn Olsen and Damini Jawaheer",
year = "2015",
month = dec,
day = "18",
doi = "10.1371/journal.pone.0145204",
language = "English",
volume = "10",
pages = "1--15",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "12",

}

RIS

TY - JOUR

T1 - Pregnancy-Induced Changes in Systemic Gene Expression among Healthy Women and Women with Rheumatoid Arthritis

AU - Mittal, Anuradha

AU - Pachter, Lior

AU - Nelson, J. Lee

AU - Kjærgaard, Hanne

AU - Smed, Mette Kiel

AU - Gildengorin, Virginia L.

AU - Zoffmann, Vibeke

AU - Hetland, Merete Lund

AU - Jewell, Nicholas P.

AU - Olsen, Jorn

AU - Jawaheer, Damini

PY - 2015/12/18

Y1 - 2015/12/18

N2 - Background Pregnancy induces drastic biological changes systemically, and has a beneficial effect on some autoimmune conditions such as rheumatoid arthritis (RA). However, specific systemic changes that occur as a result of pregnancy have not been thoroughly examined in healthy women or women with RA. The goal of this study was to identify genes with expression patterns associated with pregnancy, compared to pre-pregnancy as baseline and determine whether those associations are modified by presence of RA. Results In our RNA sequencing (RNA-seq) dataset from 5 healthy women and 20 women with RA, normalized expression levels of 4,710 genes were significantly associated with pregnancy status (pre-pregnancy, first, second and third trimesters) over time, irrespective of presence of RA (False Discovery Rate (FDR)-Adjusted p value

AB - Background Pregnancy induces drastic biological changes systemically, and has a beneficial effect on some autoimmune conditions such as rheumatoid arthritis (RA). However, specific systemic changes that occur as a result of pregnancy have not been thoroughly examined in healthy women or women with RA. The goal of this study was to identify genes with expression patterns associated with pregnancy, compared to pre-pregnancy as baseline and determine whether those associations are modified by presence of RA. Results In our RNA sequencing (RNA-seq) dataset from 5 healthy women and 20 women with RA, normalized expression levels of 4,710 genes were significantly associated with pregnancy status (pre-pregnancy, first, second and third trimesters) over time, irrespective of presence of RA (False Discovery Rate (FDR)-Adjusted p value

UR - http://www.scopus.com/inward/record.url?scp=84956914298&partnerID=8YFLogxK

U2 - 10.1371/journal.pone.0145204

DO - 10.1371/journal.pone.0145204

M3 - Journal article

C2 - 26683605

AN - SCOPUS:84956914298

VL - 10

SP - 1

EP - 15

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 12

M1 - e0145204

ER -

ID: 160732746