Telomerers rolle ved aldersbetingede sygdomme
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Telomerers rolle ved aldersbetingede sygdomme. / Bendix, Laila; Kølvraa, Steen.
I: Ugeskrift for Laeger, Bind 172, Nr. 40, 04.10.2010, s. 2752-5.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Telomerers rolle ved aldersbetingede sygdomme
AU - Bendix, Laila
AU - Kølvraa, Steen
PY - 2010/10/4
Y1 - 2010/10/4
N2 - Telomeres are specialized DNA structures, protecting the ends of linear chromosomes. The association between telomeres and cellular aging is well-established, and it has been shown that there is a negative correlation between telomere length and chronological age for many types of human tissue. On the other hand, the association between telomere length and mortality is poor. Nevertheless, it has been suggested that telomeres may play a role in the development of many aging-related diseases. This has led to attempts to develop telomere-elongating treatment.
AB - Telomeres are specialized DNA structures, protecting the ends of linear chromosomes. The association between telomeres and cellular aging is well-established, and it has been shown that there is a negative correlation between telomere length and chronological age for many types of human tissue. On the other hand, the association between telomere length and mortality is poor. Nevertheless, it has been suggested that telomeres may play a role in the development of many aging-related diseases. This has led to attempts to develop telomere-elongating treatment.
KW - Aging
KW - Cell Aging
KW - Gene Therapy
KW - Humans
KW - Morbidity
KW - Mortality
KW - Telomerase
KW - Telomere
M3 - Tidsskriftartikel
C2 - 20926045
VL - 172
SP - 2752
EP - 2755
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 40
ER -
ID: 34212113