Should the indications for prenatal chromosome analysis be changed?
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Should the indications for prenatal chromosome analysis be changed? / Philip, J; Bang, J; Madsen, Mette.
I: British medical journal, Bind 2, Nr. 6095, 1977, s. 1117-9.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Should the indications for prenatal chromosome analysis be changed?
AU - Philip, J
AU - Bang, J
AU - Madsen, Mette
N1 - Keywords: Amniocentesis; Chromosome Aberrations; Chromosome Disorders; Evaluation Studies as Topic; Female; Fetal Diseases; Humans; Pregnancy; Prenatal Diagnosis; Risk
PY - 1977
Y1 - 1977
N2 - Amniocentesis for chromosome analysis was performed in 1086 pergnant women, 739 of whom had an increased risk of giving birth to a child with chromosome abnormalities. Such abnormalities were found in almost identical proportions among the fetuses with an increased risk (1.2%) and among those with no increased risk (1.4%). Findings in several other studies seem to confirm that there is no significant difference between the risk groups in the proportion of abnormalities found. This suggests that our current risk groups may not be the right ones, but a much larger study is needed to confirm this.
AB - Amniocentesis for chromosome analysis was performed in 1086 pergnant women, 739 of whom had an increased risk of giving birth to a child with chromosome abnormalities. Such abnormalities were found in almost identical proportions among the fetuses with an increased risk (1.2%) and among those with no increased risk (1.4%). Findings in several other studies seem to confirm that there is no significant difference between the risk groups in the proportion of abnormalities found. This suggests that our current risk groups may not be the right ones, but a much larger study is needed to confirm this.
M3 - Journal article
C2 - 589017
VL - 2
SP - 1117
EP - 1119
JO - British medical journal
JF - British medical journal
SN - 0007-1447
IS - 6095
ER -
ID: 4853578