Prevention of COPD exacerbations: medications and other controversies
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Prevention of COPD exacerbations : medications and other controversies. / Vestbo, Jørgen; Lange, Peter.
I: ERJ Open Research, Bind 1, Nr. 1, 05.2015, s. 1-6.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Prevention of COPD exacerbations
T2 - medications and other controversies
AU - Vestbo, Jørgen
AU - Lange, Peter
PY - 2015/5
Y1 - 2015/5
N2 - Exacerbations have significant impact on the morbidity and mortality of patients with chronic obstructive pulmonary disease. Most guidelines emphasise prevention of exacerbations by treatment with long-acting bronchodilators and/or anti-inflammatory drugs. Whereas most of this treatment is evidence-based, it is clear that patients differ regarding the nature of exacerbations and are likely to benefit differently from different types of treatment. In this short review, we wish to highlight this, suggest a first step in differentiating pharmacological exacerbation prevention and call for more studies in this area. Finally, we wish to highlight that there are perhaps easier ways of achieving similar success in exacerbation prevention using nonpharmacological tools.
AB - Exacerbations have significant impact on the morbidity and mortality of patients with chronic obstructive pulmonary disease. Most guidelines emphasise prevention of exacerbations by treatment with long-acting bronchodilators and/or anti-inflammatory drugs. Whereas most of this treatment is evidence-based, it is clear that patients differ regarding the nature of exacerbations and are likely to benefit differently from different types of treatment. In this short review, we wish to highlight this, suggest a first step in differentiating pharmacological exacerbation prevention and call for more studies in this area. Finally, we wish to highlight that there are perhaps easier ways of achieving similar success in exacerbation prevention using nonpharmacological tools.
U2 - 10.1183/23120541.00011-2015
DO - 10.1183/23120541.00011-2015
M3 - Review
C2 - 27730132
VL - 1
SP - 1
EP - 6
JO - ERJ Open Research
JF - ERJ Open Research
SN - 2312-0541
IS - 1
ER -
ID: 167351769