Participation bias in a randomised trial of screening for lung cancer

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Participation bias in a randomised trial of screening for lung cancer. / Hestbech, Mie Sara; Siersma, Volkert; Dirksen, Asger; Pedersen, Jesper H; Brodersen, John.

I: Lung Cancer, Bind 73, Nr. 3, 2011, s. 325-31.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hestbech, MS, Siersma, V, Dirksen, A, Pedersen, JH & Brodersen, J 2011, 'Participation bias in a randomised trial of screening for lung cancer', Lung Cancer, bind 73, nr. 3, s. 325-31. https://doi.org/10.1016/j.lungcan.2010.12.018

APA

Hestbech, M. S., Siersma, V., Dirksen, A., Pedersen, J. H., & Brodersen, J. (2011). Participation bias in a randomised trial of screening for lung cancer. Lung Cancer, 73(3), 325-31. https://doi.org/10.1016/j.lungcan.2010.12.018

Vancouver

Hestbech MS, Siersma V, Dirksen A, Pedersen JH, Brodersen J. Participation bias in a randomised trial of screening for lung cancer. Lung Cancer. 2011;73(3):325-31. https://doi.org/10.1016/j.lungcan.2010.12.018

Author

Hestbech, Mie Sara ; Siersma, Volkert ; Dirksen, Asger ; Pedersen, Jesper H ; Brodersen, John. / Participation bias in a randomised trial of screening for lung cancer. I: Lung Cancer. 2011 ; Bind 73, Nr. 3. s. 325-31.

Bibtex

@article{50c3efe4c30747949a62b0090c31b5b9,

title = "Participation bias in a randomised trial of screening for lung cancer",

abstract = "INTRODUCTION: Participation bias might affect the results and the representability of randomised controlled trials. We investigated the degree of socio-demographic and psychosocial participation bias in the Danish Lung Cancer Screening Trial (DLCST). METHODS: In DLCST the questionnaire COS-LC (Consequences of Screening in Lung Cancer) was used to measure the psychosocial aspects of screening. To investigate a difference with a comparable representative sample from the Danish population, we sent out an inclusion questionnaire to 3999 Danes in the age from 50 to 70 years randomly selected from the Central National Register. Those who completed the inclusion questionnaire and met the inclusion criteria from DLCST received the COS-LC. Those who completed the COS-LC-and thus formed a population sample comparable to DLCST - were compared to the DLCST participants on socio-demographics and psychosocial measures. RESULTS: Participation rates were high among the comparable population sample: 75.3% completed the inclusion questionnaire and 77.4% of those who were eligible completed the COS-LC. The analyses revealed differences between the DLCST participants and the comparable population sample in the following socio-demographic aspects: social group, living alone, gender, age and geographical area. DLCST participants reported less negative psychosocial aspects than the comparable population sample. CONCLUSION: The present study has shown substantial socio-demographic and psychosocial participation bias in DLCST.",

author = "Hestbech, {Mie Sara} and Volkert Siersma and Asger Dirksen and Pedersen, {Jesper H} and John Brodersen",

year = "2011",

doi = "10.1016/j.lungcan.2010.12.018",

language = "English",

volume = "73",

pages = "325--31",

journal = "Lung Cancer",

issn = "0169-5002",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

RIS

TY - JOUR

T1 - Participation bias in a randomised trial of screening for lung cancer

AU - Hestbech, Mie Sara

AU - Siersma, Volkert

AU - Dirksen, Asger

AU - Pedersen, Jesper H

AU - Brodersen, John

PY - 2011

Y1 - 2011

N2 - INTRODUCTION: Participation bias might affect the results and the representability of randomised controlled trials. We investigated the degree of socio-demographic and psychosocial participation bias in the Danish Lung Cancer Screening Trial (DLCST). METHODS: In DLCST the questionnaire COS-LC (Consequences of Screening in Lung Cancer) was used to measure the psychosocial aspects of screening. To investigate a difference with a comparable representative sample from the Danish population, we sent out an inclusion questionnaire to 3999 Danes in the age from 50 to 70 years randomly selected from the Central National Register. Those who completed the inclusion questionnaire and met the inclusion criteria from DLCST received the COS-LC. Those who completed the COS-LC-and thus formed a population sample comparable to DLCST - were compared to the DLCST participants on socio-demographics and psychosocial measures. RESULTS: Participation rates were high among the comparable population sample: 75.3% completed the inclusion questionnaire and 77.4% of those who were eligible completed the COS-LC. The analyses revealed differences between the DLCST participants and the comparable population sample in the following socio-demographic aspects: social group, living alone, gender, age and geographical area. DLCST participants reported less negative psychosocial aspects than the comparable population sample. CONCLUSION: The present study has shown substantial socio-demographic and psychosocial participation bias in DLCST.

AB - INTRODUCTION: Participation bias might affect the results and the representability of randomised controlled trials. We investigated the degree of socio-demographic and psychosocial participation bias in the Danish Lung Cancer Screening Trial (DLCST). METHODS: In DLCST the questionnaire COS-LC (Consequences of Screening in Lung Cancer) was used to measure the psychosocial aspects of screening. To investigate a difference with a comparable representative sample from the Danish population, we sent out an inclusion questionnaire to 3999 Danes in the age from 50 to 70 years randomly selected from the Central National Register. Those who completed the inclusion questionnaire and met the inclusion criteria from DLCST received the COS-LC. Those who completed the COS-LC-and thus formed a population sample comparable to DLCST - were compared to the DLCST participants on socio-demographics and psychosocial measures. RESULTS: Participation rates were high among the comparable population sample: 75.3% completed the inclusion questionnaire and 77.4% of those who were eligible completed the COS-LC. The analyses revealed differences between the DLCST participants and the comparable population sample in the following socio-demographic aspects: social group, living alone, gender, age and geographical area. DLCST participants reported less negative psychosocial aspects than the comparable population sample. CONCLUSION: The present study has shown substantial socio-demographic and psychosocial participation bias in DLCST.

U2 - 10.1016/j.lungcan.2010.12.018

DO - 10.1016/j.lungcan.2010.12.018

M3 - Journal article

C2 - 21324544

VL - 73

SP - 325

EP - 331

JO - Lung Cancer

JF - Lung Cancer

SN - 0169-5002

IS - 3

ER -

ID: 33206003

Institut for Folkesundhedsvidenskab