TY - JOUR

T1 - Characterization of persistent post-traumatic headache and management strategies in adolescents and young adults following mild traumatic brain injury

AU - Kothari, Simple Futarmal

AU - Eggertsen, Peter Preben

AU - Frederiksen, Oana Veronica

AU - Thastum, Mille Moeller

AU - Svendsen, Susanne Wulff

AU - Tuborgh, Astrid

AU - Naess-Schmidt, Erhard Trillingsgaard

AU - Rask, Charlotte Ulrikka

AU - Schroeder, Andreas

AU - Kasch, Helge

AU - Nielsen, Jorgen Feldbaek

PY - 2022

Y1 - 2022

N2 - Characteristics of persistent post-traumatic headache (PTH) in young individuals are poorly known leading to diagnostic problems and diverse management. We aimed to describe headache phenotypes and self-reported management strategies in young individuals with PTH following mild traumatic brain injury (mTBI). A comprehensive structured questionnaire was used to evaluate headache phenotypes/characteristics and management strategies to relieve headache in 107, 15-30-year-old individuals with PTH. Around 4 months post-injury, migraine-like headache in combination with tension-type like headache (40%) was the most commonly encountered headache phenotype followed by migraine-like headache (36%). Around 50% reported aura-like symptoms before/during the headache attack. Medication-overuse headache was diagnosed in 10%. Stress, sleep disturbances, and bright lights were the most common trigger factors. More than 80% reported that their headache was worsened by work-related activity and alleviated by rest/lying down. Simple analgesics were commonly used (88%) whereas prophylactic drugs were rarely used (5%). Bedrest and physiotherapy were also commonly used as management strategies by 56% and 34% of the participants, respectively. In conclusion, most young individuals with PTH after mTBI presented with combined migraine-like and tension-type-like headache followed by migraine-like headache, only. Preventive headache medication was rarely used, while simple analgesics and bedrest were commonly used for short-term headache relief.

AB - Characteristics of persistent post-traumatic headache (PTH) in young individuals are poorly known leading to diagnostic problems and diverse management. We aimed to describe headache phenotypes and self-reported management strategies in young individuals with PTH following mild traumatic brain injury (mTBI). A comprehensive structured questionnaire was used to evaluate headache phenotypes/characteristics and management strategies to relieve headache in 107, 15-30-year-old individuals with PTH. Around 4 months post-injury, migraine-like headache in combination with tension-type like headache (40%) was the most commonly encountered headache phenotype followed by migraine-like headache (36%). Around 50% reported aura-like symptoms before/during the headache attack. Medication-overuse headache was diagnosed in 10%. Stress, sleep disturbances, and bright lights were the most common trigger factors. More than 80% reported that their headache was worsened by work-related activity and alleviated by rest/lying down. Simple analgesics were commonly used (88%) whereas prophylactic drugs were rarely used (5%). Bedrest and physiotherapy were also commonly used as management strategies by 56% and 34% of the participants, respectively. In conclusion, most young individuals with PTH after mTBI presented with combined migraine-like and tension-type-like headache followed by migraine-like headache, only. Preventive headache medication was rarely used, while simple analgesics and bedrest were commonly used for short-term headache relief.

KW - POST-CONCUSSION SYMPTOMS

KW - NATURAL-HISTORY

KW - US SOLDIERS

KW - MIGRAINE

KW - IMPACT

KW - KINEMATICS

KW - CHILDREN

KW - WOMEN

KW - RISK

KW - AURA

U2 - 10.1038/s41598-022-05187-x

DO - 10.1038/s41598-022-05187-x

M3 - Journal article

C2 - 35140235

VL - 12

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 2209

ER -