A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat

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Standard

A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat. / Mohr, H; Kragstrup, J.

I: Journal of Dental Research, Bind 70, Nr. 6, 06.1991, s. 957-60.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Mohr, H & Kragstrup, J 1991, 'A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat', Journal of Dental Research, bind 70, nr. 6, s. 957-60. https://doi.org/10.1177/00220345910700060901

APA

Mohr, H., & Kragstrup, J. (1991). A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat. Journal of Dental Research, 70(6), 957-60. https://doi.org/10.1177/00220345910700060901

Vancouver

Mohr H, Kragstrup J. A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat. Journal of Dental Research. 1991 jun.;70(6):957-60. https://doi.org/10.1177/00220345910700060901

Author

Mohr, H ; Kragstrup, J. / A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat. I: Journal of Dental Research. 1991 ; Bind 70, Nr. 6. s. 957-60.

Bibtex

@article{65ba39feb74e45418311f978cf0600ec,
title = "A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat",
abstract = "Ectopic bone formation was induced in 14 rats receiving 100 ppm fluoride in drinking water and in 14 control animals. Sections from ossicles removed after 14 and 20 days were sampled for stereological analysis. Bone volume density and bone volume were reduced in experimental animals on day 14 (p less than 0.05). This difference was no longer present after 20 days. On day 20, surface density and areas of formative surfaces were increased in the fluoride group (p less than 0.05). Osteoid seam thickness was higher in the fluoride group on both days (p less than 0.01). In conclusion, fluoride induced quantitative alterations in ectopic bone formation, and the presented model may prove a useful addendum to previous methods for investigation of fluoride effects on mineralization processes in vivo.",
keywords = "Animals, Bone Matrix/drug effects, Bone and Bones/drug effects, Cartilage/drug effects, Fluorides/administration & dosage, Male, Osteoblasts/drug effects, Osteogenesis/drug effects, Rats, Rats, Inbred Strains, Skin, Time Factors",
author = "H Mohr and J Kragstrup",
year = "1991",
month = jun,
doi = "10.1177/00220345910700060901",
language = "English",
volume = "70",
pages = "957--60",
journal = "Advances in dental research",
issn = "0895-9374",
publisher = "International and American Associations for Dental Research",
number = "6",

}

RIS

TY - JOUR

T1 - A histomorphometric analysis of the effects of fluoride on experimental ectopic bone formation in the rat

AU - Mohr, H

AU - Kragstrup, J

PY - 1991/6

Y1 - 1991/6

N2 - Ectopic bone formation was induced in 14 rats receiving 100 ppm fluoride in drinking water and in 14 control animals. Sections from ossicles removed after 14 and 20 days were sampled for stereological analysis. Bone volume density and bone volume were reduced in experimental animals on day 14 (p less than 0.05). This difference was no longer present after 20 days. On day 20, surface density and areas of formative surfaces were increased in the fluoride group (p less than 0.05). Osteoid seam thickness was higher in the fluoride group on both days (p less than 0.01). In conclusion, fluoride induced quantitative alterations in ectopic bone formation, and the presented model may prove a useful addendum to previous methods for investigation of fluoride effects on mineralization processes in vivo.

AB - Ectopic bone formation was induced in 14 rats receiving 100 ppm fluoride in drinking water and in 14 control animals. Sections from ossicles removed after 14 and 20 days were sampled for stereological analysis. Bone volume density and bone volume were reduced in experimental animals on day 14 (p less than 0.05). This difference was no longer present after 20 days. On day 20, surface density and areas of formative surfaces were increased in the fluoride group (p less than 0.05). Osteoid seam thickness was higher in the fluoride group on both days (p less than 0.01). In conclusion, fluoride induced quantitative alterations in ectopic bone formation, and the presented model may prove a useful addendum to previous methods for investigation of fluoride effects on mineralization processes in vivo.

KW - Animals

KW - Bone Matrix/drug effects

KW - Bone and Bones/drug effects

KW - Cartilage/drug effects

KW - Fluorides/administration & dosage

KW - Male

KW - Osteoblasts/drug effects

KW - Osteogenesis/drug effects

KW - Rats

KW - Rats, Inbred Strains

KW - Skin

KW - Time Factors

U2 - 10.1177/00220345910700060901

DO - 10.1177/00220345910700060901

M3 - Journal article

C2 - 2045575

VL - 70

SP - 957

EP - 960

JO - Advances in dental research

JF - Advances in dental research

SN - 0895-9374

IS - 6

ER -

ID: 324188700