Equipercentile equating of scores from common patient-reported outcome measures of physical function in patients with cancer

Research output: Contribution to journalJournal articleResearchpeer-review

  • Maria Rothmund
  • Micha J Pilz
  • Lisa Schlosser
  • Juan I Arraras
  • Grønvold, Mogens
  • Bernhard Holzner
  • Marieke van Leeuwen
  • Morten Aa Petersen
  • Heike Schmidt
  • Teresa Young
  • Matthias Rose
  • David Cella
  • Johannes M Giesinger
  • EORTC Quality of Life Group

OBJECTIVE: To provide equipercentile equating of physical function (PF) scores from frequently used PROMs in cancer patients to facilitate data pooling and comparisons.

STUDY DESIGN AND SETTING: Adult cancer patients from five European countries completed the EORTC CAT Core, EORTC QLQ-C30, FACT-G, SF-36, and the PROMIS Physical Function 20a short form. The R package "equate" was used to establish conversion tables of PF scores on those measures with a bivariate rank correlation of at least 0.75.

RESULTS: In total, 953 patients with cancer (mean age 58.9 years, 54.7% men) participated. Bivariate rank correlations between PF scores from the EORTC CAT Core, EORTC QLQ-C30, SF-36, and PROMIS were all above 0.85, but below 0.69 for the FACT-G. Conversion tables were established for all measures but the FACT-G. These tables indicate which score from one PROM best matches the score from another PROM and provide standard errors of converted scores.

CONCLUSION: Our analysis indicates that linking of PF scores from both EORTC measures (CAT and QLQ-C30) with PROMIS and SF-36 is possible whereas the physical domain of the FACT-G seems to be different. The established conversion tables may be used for comparing results or pooling data from clinical studies using different PROMs.

Original languageEnglish
Article number111203
JournalJournal of Clinical Epidemiology
Volume165
Number of pages12
ISSN0895-4356
DOIs
Publication statusPublished - 2024

Bibliographical note

Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.

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