Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes?

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Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes? / Osler, Merete; Kriegbaum, Margit; Christensen, Ulla; Holstein, Bjørn; Andersen, Anne-Marie Nybo.

In: Annals of Epidemiology, Vol. 18, No. 5, 2008, p. 422-424.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Osler, M, Kriegbaum, M, Christensen, U, Holstein, B & Andersen, A-MN 2008, 'Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes?', Annals of Epidemiology, vol. 18, no. 5, pp. 422-424. https://doi.org/10.1016/j.annepidem.2007.12.008

APA

Osler, M., Kriegbaum, M., Christensen, U., Holstein, B., & Andersen, A-M. N. (2008). Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes? Annals of Epidemiology, 18(5), 422-424. https://doi.org/10.1016/j.annepidem.2007.12.008

Vancouver

Osler M, Kriegbaum M, Christensen U, Holstein B, Andersen A-MN. Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes? Annals of Epidemiology. 2008;18(5):422-424. https://doi.org/10.1016/j.annepidem.2007.12.008

Author

Osler, Merete ; Kriegbaum, Margit ; Christensen, Ulla ; Holstein, Bjørn ; Andersen, Anne-Marie Nybo. / Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes?. In: Annals of Epidemiology. 2008 ; Vol. 18, No. 5. pp. 422-424.

Bibtex

@article{8aa3d050653011dd8d9f000ea68e967b,
title = "Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes?",
abstract = "PURPOSE: To examine the consequences of non-response in a follow-up survey for associations between early-life factors and lifestyle-related health outcomes in adulthood. METHODS: In a cohort of 11532 Danish men born in 1953 we had nearly complete follow-up in the National Patient Register, but only 66{\%} of 9507 eligible cohort members participated in a follow-up survey, in 2004. We examined whether characteristics measured early in life and discharge from hospital for alcohol abuse or tobacco-related lung diseases, were associated with survey response. Associations between the early-life characteristics and these two health outcomes were calculated in the entire cohort and among responders, and the effect of non-response was described by a Relative Odd Ratio (ROR=OR(responders)/OR(entire cohort)). RESULTS: A low response rate at age 50 years was related to having a single mother at birth, low educational attainment at age 18, and low cognitive function at ages 12 and 18. The risk of alcohol overuse and tobacco-related diseases was also highest among non-responders. However, the associations between early-life characteristics and the outcomes were nearly the same in responders as in the entire cohort. CONCLUSIONS: Although non-responders differed from responders in terms of early-life exposures and incidence of the lifestyle-related outcomes, we found no overt effects of this on the exposure-risk associations.",
author = "Merete Osler and Margit Kriegbaum and Ulla Christensen and Bj{\o}rn Holstein and Andersen, {Anne-Marie Nybo}",
note = "Keywords: Cognition; Cohort Studies; Denmark; Epidemiologic Methods; Family Characteristics; Follow-Up Studies; Humans; Life Style; Male; Middle Aged; Odds Ratio; Patient Dropouts; Research Subjects; Selection Bias",
year = "2008",
doi = "10.1016/j.annepidem.2007.12.008",
language = "English",
volume = "18",
pages = "422--424",
journal = "Annals of Epidemiology",
issn = "1047-2797",
publisher = "Elsevier",
number = "5",

}

RIS

TY - JOUR

T1 - Rapid report on methodology: does loss to follow-up in a cohort study bias associations between early life factors and lifestyle-related health outcomes?

AU - Osler, Merete

AU - Kriegbaum, Margit

AU - Christensen, Ulla

AU - Holstein, Bjørn

AU - Andersen, Anne-Marie Nybo

N1 - Keywords: Cognition; Cohort Studies; Denmark; Epidemiologic Methods; Family Characteristics; Follow-Up Studies; Humans; Life Style; Male; Middle Aged; Odds Ratio; Patient Dropouts; Research Subjects; Selection Bias

PY - 2008

Y1 - 2008

N2 - PURPOSE: To examine the consequences of non-response in a follow-up survey for associations between early-life factors and lifestyle-related health outcomes in adulthood. METHODS: In a cohort of 11532 Danish men born in 1953 we had nearly complete follow-up in the National Patient Register, but only 66% of 9507 eligible cohort members participated in a follow-up survey, in 2004. We examined whether characteristics measured early in life and discharge from hospital for alcohol abuse or tobacco-related lung diseases, were associated with survey response. Associations between the early-life characteristics and these two health outcomes were calculated in the entire cohort and among responders, and the effect of non-response was described by a Relative Odd Ratio (ROR=OR(responders)/OR(entire cohort)). RESULTS: A low response rate at age 50 years was related to having a single mother at birth, low educational attainment at age 18, and low cognitive function at ages 12 and 18. The risk of alcohol overuse and tobacco-related diseases was also highest among non-responders. However, the associations between early-life characteristics and the outcomes were nearly the same in responders as in the entire cohort. CONCLUSIONS: Although non-responders differed from responders in terms of early-life exposures and incidence of the lifestyle-related outcomes, we found no overt effects of this on the exposure-risk associations.

AB - PURPOSE: To examine the consequences of non-response in a follow-up survey for associations between early-life factors and lifestyle-related health outcomes in adulthood. METHODS: In a cohort of 11532 Danish men born in 1953 we had nearly complete follow-up in the National Patient Register, but only 66% of 9507 eligible cohort members participated in a follow-up survey, in 2004. We examined whether characteristics measured early in life and discharge from hospital for alcohol abuse or tobacco-related lung diseases, were associated with survey response. Associations between the early-life characteristics and these two health outcomes were calculated in the entire cohort and among responders, and the effect of non-response was described by a Relative Odd Ratio (ROR=OR(responders)/OR(entire cohort)). RESULTS: A low response rate at age 50 years was related to having a single mother at birth, low educational attainment at age 18, and low cognitive function at ages 12 and 18. The risk of alcohol overuse and tobacco-related diseases was also highest among non-responders. However, the associations between early-life characteristics and the outcomes were nearly the same in responders as in the entire cohort. CONCLUSIONS: Although non-responders differed from responders in terms of early-life exposures and incidence of the lifestyle-related outcomes, we found no overt effects of this on the exposure-risk associations.

U2 - 10.1016/j.annepidem.2007.12.008

DO - 10.1016/j.annepidem.2007.12.008

M3 - Journal article

C2 - 18329893

VL - 18

SP - 422

EP - 424

JO - Annals of Epidemiology

JF - Annals of Epidemiology

SN - 1047-2797

IS - 5

ER -

ID: 5398423