Applied mediation analyses: a review and tutorial

Research output: Contribution to journal › Review › Research › peer-review

Standard

Applied mediation analyses : a review and tutorial. / Lange, Theis; Hansen, Kim Wadt; Sørensen, Rikke; Galatius, Søren.

In: Epidemiology and health, Vol. 39, e2017035, 06.08.2017, p. 1-13.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Lange, T, Hansen, KW, Sørensen, R & Galatius, S 2017, 'Applied mediation analyses: a review and tutorial', Epidemiology and health, vol. 39, e2017035, pp. 1-13. https://doi.org/10.4178/epih.e2017035

APA

Lange, T., Hansen, K. W., Sørensen, R., & Galatius, S. (2017). Applied mediation analyses: a review and tutorial. Epidemiology and health, 39, 1-13. [e2017035]. https://doi.org/10.4178/epih.e2017035

Vancouver

Lange T, Hansen KW, Sørensen R, Galatius S. Applied mediation analyses: a review and tutorial. Epidemiology and health. 2017 Aug 6;39:1-13. e2017035. https://doi.org/10.4178/epih.e2017035

Author

Lange, Theis ; Hansen, Kim Wadt ; Sørensen, Rikke ; Galatius, Søren. / Applied mediation analyses : a review and tutorial. In: Epidemiology and health. 2017 ; Vol. 39. pp. 1-13.

Bibtex

@article{9a07ad57f3744f56b98fd6b91700cf7a,
title = "Applied mediation analyses: a review and tutorial",
abstract = "In recent years, mediation analysis has emerged as a powerful tool to disentangle causal pathways from an exposure/treatment to clinically relevant outcomes. Mediation analysis has been applied in scientific fields as diverse as labour market relations and randomized clinical trials of heart disease treatments. In parallel to these applications, the underlying mathematical theory and computer tools have been refined. This combined review and tutorial will introduce the reader to modern mediation analysis including: the mathematical framework; required assumptions; and software implementation in the R package medflex. All results are illustrated using a recent study on the causal pathways stemming from the early invasive treatment of acute coronary syndrome, for which the rich Danish population registers allow us to follow patients' medication use and more after being discharged from hospital.",
keywords = "Journal Article, Review",
author = "Theis Lange and Hansen, {Kim Wadt} and Rikke S{\o}rensen and S{\o}ren Galatius",
year = "2017",
month = aug,
day = "6",
doi = "10.4178/epih.e2017035",
language = "English",
volume = "39",
pages = "1--13",
journal = "Epidemiology and health",
issn = "2092-7193",
publisher = "Korean Society of Epidemiology",

}

RIS

TY - JOUR

T1 - Applied mediation analyses

T2 - a review and tutorial

AU - Lange, Theis

AU - Hansen, Kim Wadt

AU - Sørensen, Rikke

AU - Galatius, Søren

PY - 2017/8/6

Y1 - 2017/8/6

N2 - In recent years, mediation analysis has emerged as a powerful tool to disentangle causal pathways from an exposure/treatment to clinically relevant outcomes. Mediation analysis has been applied in scientific fields as diverse as labour market relations and randomized clinical trials of heart disease treatments. In parallel to these applications, the underlying mathematical theory and computer tools have been refined. This combined review and tutorial will introduce the reader to modern mediation analysis including: the mathematical framework; required assumptions; and software implementation in the R package medflex. All results are illustrated using a recent study on the causal pathways stemming from the early invasive treatment of acute coronary syndrome, for which the rich Danish population registers allow us to follow patients' medication use and more after being discharged from hospital.

AB - In recent years, mediation analysis has emerged as a powerful tool to disentangle causal pathways from an exposure/treatment to clinically relevant outcomes. Mediation analysis has been applied in scientific fields as diverse as labour market relations and randomized clinical trials of heart disease treatments. In parallel to these applications, the underlying mathematical theory and computer tools have been refined. This combined review and tutorial will introduce the reader to modern mediation analysis including: the mathematical framework; required assumptions; and software implementation in the R package medflex. All results are illustrated using a recent study on the causal pathways stemming from the early invasive treatment of acute coronary syndrome, for which the rich Danish population registers allow us to follow patients' medication use and more after being discharged from hospital.

KW - Journal Article

KW - Review

U2 - 10.4178/epih.e2017035

DO - 10.4178/epih.e2017035

M3 - Review

C2 - 29121709

VL - 39

SP - 1

EP - 13

JO - Epidemiology and health

JF - Epidemiology and health

SN - 2092-7193

M1 - e2017035

ER -

ID: 185847797