Self-Rated Health as a Predictor of Death after Two Years: The Importance of Physical and Mental Wellbeing Postintensive Care
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Self-Rated Health as a Predictor of Death after Two Years : The Importance of Physical and Mental Wellbeing Postintensive Care. / Vejen, Marie; Bjorner, Jakob B.; Bestle, Morten H.; Lindhardt, Anne; Jensen, Jens U.
I: Journal of Biomedicine and Biotechnology, Bind 2017, Nr. (2017), 5192640, 21.08.2017, s. 1-9.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Self-Rated Health as a Predictor of Death after Two Years
T2 - The Importance of Physical and Mental Wellbeing Postintensive Care
AU - Vejen, Marie
AU - Bjorner, Jakob B.
AU - Bestle, Morten H.
AU - Lindhardt, Anne
AU - Jensen, Jens U.
PY - 2017/8/21
Y1 - 2017/8/21
N2 - Introduction. The objective of this study is, among half-year intensive care survivors, to determine whether self-assessment of health can predict two-year mortality. Methods. The study is a prospective cohort study based on the Procalcitonin and Survival Study trial. Half-year survivors from this 1200-patient multicenter intensive care trial were sent the SF-36 questionnaire. We used both a simple one-item question and multiple questions summarized as a Physical Component Summary (PCS) and a Mental Component Summary (MCS) score. The responders were followed for vital status 730 days after inclusion. Answers were dichotomized into a low-risk and a high-risk group and hazard ratios (HR) with 95% confidence interval (CI) were calculated by Cox proportional hazard analyses. Conclusion. We found that self-rated health measured by a single question was a strong independent predictor of two-year all-cause mortality (HR: 1.8; 95% CI: 1.1–3.0). The multi-item component scores of the SF-36 also predicted two-year mortality (PCS: HR: 2.9; 95% CI 1.7–5.0) (MCS: HR: 1.9; 95% CI 1.1–3.4). These results suggest that self-rated health questions could help in identifying patients at excess risk. Randomized controlled trials are needed to test whether our findings represent causality.
AB - Introduction. The objective of this study is, among half-year intensive care survivors, to determine whether self-assessment of health can predict two-year mortality. Methods. The study is a prospective cohort study based on the Procalcitonin and Survival Study trial. Half-year survivors from this 1200-patient multicenter intensive care trial were sent the SF-36 questionnaire. We used both a simple one-item question and multiple questions summarized as a Physical Component Summary (PCS) and a Mental Component Summary (MCS) score. The responders were followed for vital status 730 days after inclusion. Answers were dichotomized into a low-risk and a high-risk group and hazard ratios (HR) with 95% confidence interval (CI) were calculated by Cox proportional hazard analyses. Conclusion. We found that self-rated health measured by a single question was a strong independent predictor of two-year all-cause mortality (HR: 1.8; 95% CI: 1.1–3.0). The multi-item component scores of the SF-36 also predicted two-year mortality (PCS: HR: 2.9; 95% CI 1.7–5.0) (MCS: HR: 1.9; 95% CI 1.1–3.4). These results suggest that self-rated health questions could help in identifying patients at excess risk. Randomized controlled trials are needed to test whether our findings represent causality.
U2 - 10.1155/2017/5192640
DO - 10.1155/2017/5192640
M3 - Journal article
C2 - 28904962
VL - 2017
SP - 1
EP - 9
JO - BioMed Research International
JF - BioMed Research International
SN - 2314-6133
IS - (2017)
M1 - 5192640
ER -
ID: 188226983