Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust

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Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust. / Giesinger, Johannes M.; Kieffer, Jacobien M.; Fayers, Peter M.; Groenvold, Mogens; Petersen, Morten Aa.; Scott, Neil W.; Sprangers, Mirjam A. G.; Velikova, Galina; Aaronson, Neil K.; EORTC Quality of Life Group.

I: Journal of Clinical Epidemiology, Bind 69, 01.2016, s. 79–88.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Giesinger, JM, Kieffer, JM, Fayers, PM, Groenvold, M, Petersen, MA, Scott, NW, Sprangers, MAG, Velikova, G, Aaronson, NK & EORTC Quality of Life Group 2016, 'Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust', Journal of Clinical Epidemiology, bind 69, s. 79–88. https://doi.org/10.1016/j.jclinepi.2015.08.007

APA

Giesinger, J. M., Kieffer, J. M., Fayers, P. M., Groenvold, M., Petersen, M. A., Scott, N. W., Sprangers, M. A. G., Velikova, G., Aaronson, N. K., & EORTC Quality of Life Group (2016). Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust. Journal of Clinical Epidemiology, 69, 79–88. https://doi.org/10.1016/j.jclinepi.2015.08.007

Vancouver

Giesinger JM, Kieffer JM, Fayers PM, Groenvold M, Petersen MA, Scott NW o.a. Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust. Journal of Clinical Epidemiology. 2016 jan.;69:79–88. https://doi.org/10.1016/j.jclinepi.2015.08.007

Author

Giesinger, Johannes M. ; Kieffer, Jacobien M. ; Fayers, Peter M. ; Groenvold, Mogens ; Petersen, Morten Aa. ; Scott, Neil W. ; Sprangers, Mirjam A. G. ; Velikova, Galina ; Aaronson, Neil K. ; EORTC Quality of Life Group. / Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust. I: Journal of Clinical Epidemiology. 2016 ; Bind 69. s. 79–88.

Bibtex

@article{408cc807ea6b428b825afb229cc317ca,
title = "Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust",
abstract = "OBJECTIVE: To further evaluate the higher order measurement structure of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30), with the aim of generating a summary score.STUDY DESIGN AND SETTING: Using pretreatment QLQ-C30 data (N = 3,282), we conducted confirmatory factor analyses to test seven previously evaluated higher order models. We compared the summary score(s) derived from the best performing higher order model with the original QLQ-C30 scale scores, using tumor stage, performance status, and change over time (N = 244) as grouping variables.RESULTS: Although all models showed acceptable fit, we continued in the interest of parsimony with known-groups validity and responsiveness analyses using a summary score derived from the single higher order factor model. The validity and responsiveness of this QLQ-C30 summary score was equal to, and in many cases superior to the original, underlying QLQ-C30 scale scores.CONCLUSION: Our results provide empirical support for a measurement model for the QLQ-C30 yielding a single summary score. The availability of this summary score can avoid problems with potential type I errors that arise because of multiple testing when making comparisons based on the 15 outcomes generated by this questionnaire and may reduce sample size requirements for health-related quality of life studies using the QLQ-C30 questionnaire when an overall summary score is a relevant primary outcome.",
author = "Giesinger, {Johannes M.} and Kieffer, {Jacobien M.} and Fayers, {Peter M.} and Mogens Groenvold and Petersen, {Morten Aa.} and Scott, {Neil W.} and Sprangers, {Mirjam A. G.} and Galina Velikova and Aaronson, {Neil K.} and {EORTC Quality of Life Group}",
note = "Copyright {\textcopyright} 2015 Elsevier Inc. All rights reserved.",
year = "2016",
month = jan,
doi = "10.1016/j.jclinepi.2015.08.007",
language = "English",
volume = "69",
pages = "79–88",
journal = "Journal of Clinical Epidemiology",
issn = "0895-4356",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust

AU - Giesinger, Johannes M.

AU - Kieffer, Jacobien M.

AU - Fayers, Peter M.

AU - Groenvold, Mogens

AU - Petersen, Morten Aa.

AU - Scott, Neil W.

AU - Sprangers, Mirjam A. G.

AU - Velikova, Galina

AU - Aaronson, Neil K.

AU - EORTC Quality of Life Group

N1 - Copyright © 2015 Elsevier Inc. All rights reserved.

PY - 2016/1

Y1 - 2016/1

N2 - OBJECTIVE: To further evaluate the higher order measurement structure of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30), with the aim of generating a summary score.STUDY DESIGN AND SETTING: Using pretreatment QLQ-C30 data (N = 3,282), we conducted confirmatory factor analyses to test seven previously evaluated higher order models. We compared the summary score(s) derived from the best performing higher order model with the original QLQ-C30 scale scores, using tumor stage, performance status, and change over time (N = 244) as grouping variables.RESULTS: Although all models showed acceptable fit, we continued in the interest of parsimony with known-groups validity and responsiveness analyses using a summary score derived from the single higher order factor model. The validity and responsiveness of this QLQ-C30 summary score was equal to, and in many cases superior to the original, underlying QLQ-C30 scale scores.CONCLUSION: Our results provide empirical support for a measurement model for the QLQ-C30 yielding a single summary score. The availability of this summary score can avoid problems with potential type I errors that arise because of multiple testing when making comparisons based on the 15 outcomes generated by this questionnaire and may reduce sample size requirements for health-related quality of life studies using the QLQ-C30 questionnaire when an overall summary score is a relevant primary outcome.

AB - OBJECTIVE: To further evaluate the higher order measurement structure of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30), with the aim of generating a summary score.STUDY DESIGN AND SETTING: Using pretreatment QLQ-C30 data (N = 3,282), we conducted confirmatory factor analyses to test seven previously evaluated higher order models. We compared the summary score(s) derived from the best performing higher order model with the original QLQ-C30 scale scores, using tumor stage, performance status, and change over time (N = 244) as grouping variables.RESULTS: Although all models showed acceptable fit, we continued in the interest of parsimony with known-groups validity and responsiveness analyses using a summary score derived from the single higher order factor model. The validity and responsiveness of this QLQ-C30 summary score was equal to, and in many cases superior to the original, underlying QLQ-C30 scale scores.CONCLUSION: Our results provide empirical support for a measurement model for the QLQ-C30 yielding a single summary score. The availability of this summary score can avoid problems with potential type I errors that arise because of multiple testing when making comparisons based on the 15 outcomes generated by this questionnaire and may reduce sample size requirements for health-related quality of life studies using the QLQ-C30 questionnaire when an overall summary score is a relevant primary outcome.

U2 - 10.1016/j.jclinepi.2015.08.007

DO - 10.1016/j.jclinepi.2015.08.007

M3 - Journal article

C2 - 26327487

VL - 69

SP - 79

EP - 88

JO - Journal of Clinical Epidemiology

JF - Journal of Clinical Epidemiology

SN - 0895-4356

ER -

ID: 151437431