Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting

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Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting. / Rasmussen, Jon B; Nordin, Lovisa S; Rasmussen, Niclas S; Thomsen, Jakúp A; Street, Laura A; Bygbjerg, Ib C; Christensen, Dirk Lund.

I: Tropical Medicine & International Health, Bind 19, Nr. 12, 08.10.2014, s. 1515-19.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Rasmussen, JB, Nordin, LS, Rasmussen, NS, Thomsen, JA, Street, LA, Bygbjerg, IC & Christensen, DL 2014, 'Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting', Tropical Medicine & International Health, bind 19, nr. 12, s. 1515-19. https://doi.org/10.1111/tmi.12391

APA

Rasmussen, J. B., Nordin, L. S., Rasmussen, N. S., Thomsen, J. A., Street, L. A., Bygbjerg, I. C., & Christensen, D. L. (2014). Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting. Tropical Medicine & International Health, 19(12), 1515-19. https://doi.org/10.1111/tmi.12391

Vancouver

Rasmussen JB, Nordin LS, Rasmussen NS, Thomsen JA, Street LA, Bygbjerg IC o.a. Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting. Tropical Medicine & International Health. 2014 okt. 8;19(12):1515-19. https://doi.org/10.1111/tmi.12391

Author

Rasmussen, Jon B ; Nordin, Lovisa S ; Rasmussen, Niclas S ; Thomsen, Jakúp A ; Street, Laura A ; Bygbjerg, Ib C ; Christensen, Dirk Lund. / Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting. I: Tropical Medicine & International Health. 2014 ; Bind 19, Nr. 12. s. 1515-19.

Bibtex

@article{fa766923025d4ea98bf33f4bdb034ee7,

title = "Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting",

abstract = "OBJECTIVES: To investigate the diagnostic accuracy of random blood glucose (RBG) on good glycaemic control among patients with diabetes mellitus (DM) in a rural African setting.METHODS: Cross-sectional study at St. Francis' Hospital in eastern Zambia. RBG and HbA1c were measured during one clinical review only. Other information obtained was age, sex, body mass index, waist circumference, blood pressure, urine albumin-creatinine ratio, duration since diagnosis and medication.RESULTS: One hundred and one patients with DM (type 1 DM = 23, type 2 DM = 78) were included. Spearman's rank correlation coefficient revealed a significant correlation between RBG and HbA1c among the patients with type 2 DM (r = 0.73, P < 0.001) but not patients with type 1 DM (r = 0.17, P = 0.44). Furthermore, in a multivariate linear regression model (R(2) = 0.71) RBG (per mmol/l increment) (B = 0.28, 95% CI:0.24-0.32, P < 0.001) was significantly associated with HbA1c among the patients with type 2 DM. Based on ROC analysis (AUC = 0.80, SE = 0.05), RBG ≤7.5 mmol/l was determined as the optimal cut-off value for good glycaemic control (HbA1c <7.0% [53 mmol/mol]) among patients with type 2 DM (sensitivity = 76.7%; specificity = 70.8%; positive predictive value = 62.2%; negative predictive value = 82.9%).CONCLUSIONS: Random blood glucose could possibly be used to assess glycaemic control among patients with type 2 DM in rural settings of sub-Saharan Africa.",

author = "Rasmussen, {Jon B} and Nordin, {Lovisa S} and Rasmussen, {Niclas S} and Thomsen, {Jak{\'u}p A} and Street, {Laura A} and Bygbjerg, {Ib C} and Christensen, {Dirk Lund}",

note = "{\textcopyright} 2014 John Wiley & Sons Ltd.",

year = "2014",

month = oct,

day = "8",

doi = "10.1111/tmi.12391",

language = "English",

volume = "19",

pages = "1515--19",

journal = "Tropical Medicine & International Health",

issn = "1360-2276",

publisher = "Wiley-Blackwell",

number = "12",

}

RIS

TY - JOUR

T1 - Random blood glucose may be used to assess long-term glycaemic control among patients with type 2 diabetes mellitus in a rural African clinical setting

AU - Rasmussen, Jon B

AU - Nordin, Lovisa S

AU - Rasmussen, Niclas S

AU - Thomsen, Jakúp A

AU - Street, Laura A

AU - Bygbjerg, Ib C

AU - Christensen, Dirk Lund

PY - 2014/10/8

Y1 - 2014/10/8

N2 - OBJECTIVES: To investigate the diagnostic accuracy of random blood glucose (RBG) on good glycaemic control among patients with diabetes mellitus (DM) in a rural African setting.METHODS: Cross-sectional study at St. Francis' Hospital in eastern Zambia. RBG and HbA1c were measured during one clinical review only. Other information obtained was age, sex, body mass index, waist circumference, blood pressure, urine albumin-creatinine ratio, duration since diagnosis and medication.RESULTS: One hundred and one patients with DM (type 1 DM = 23, type 2 DM = 78) were included. Spearman's rank correlation coefficient revealed a significant correlation between RBG and HbA1c among the patients with type 2 DM (r = 0.73, P < 0.001) but not patients with type 1 DM (r = 0.17, P = 0.44). Furthermore, in a multivariate linear regression model (R(2) = 0.71) RBG (per mmol/l increment) (B = 0.28, 95% CI:0.24-0.32, P < 0.001) was significantly associated with HbA1c among the patients with type 2 DM. Based on ROC analysis (AUC = 0.80, SE = 0.05), RBG ≤7.5 mmol/l was determined as the optimal cut-off value for good glycaemic control (HbA1c <7.0% [53 mmol/mol]) among patients with type 2 DM (sensitivity = 76.7%; specificity = 70.8%; positive predictive value = 62.2%; negative predictive value = 82.9%).CONCLUSIONS: Random blood glucose could possibly be used to assess glycaemic control among patients with type 2 DM in rural settings of sub-Saharan Africa.

AB - OBJECTIVES: To investigate the diagnostic accuracy of random blood glucose (RBG) on good glycaemic control among patients with diabetes mellitus (DM) in a rural African setting.METHODS: Cross-sectional study at St. Francis' Hospital in eastern Zambia. RBG and HbA1c were measured during one clinical review only. Other information obtained was age, sex, body mass index, waist circumference, blood pressure, urine albumin-creatinine ratio, duration since diagnosis and medication.RESULTS: One hundred and one patients with DM (type 1 DM = 23, type 2 DM = 78) were included. Spearman's rank correlation coefficient revealed a significant correlation between RBG and HbA1c among the patients with type 2 DM (r = 0.73, P < 0.001) but not patients with type 1 DM (r = 0.17, P = 0.44). Furthermore, in a multivariate linear regression model (R(2) = 0.71) RBG (per mmol/l increment) (B = 0.28, 95% CI:0.24-0.32, P < 0.001) was significantly associated with HbA1c among the patients with type 2 DM. Based on ROC analysis (AUC = 0.80, SE = 0.05), RBG ≤7.5 mmol/l was determined as the optimal cut-off value for good glycaemic control (HbA1c <7.0% [53 mmol/mol]) among patients with type 2 DM (sensitivity = 76.7%; specificity = 70.8%; positive predictive value = 62.2%; negative predictive value = 82.9%).CONCLUSIONS: Random blood glucose could possibly be used to assess glycaemic control among patients with type 2 DM in rural settings of sub-Saharan Africa.

U2 - 10.1111/tmi.12391

DO - 10.1111/tmi.12391

M3 - Journal article

C2 - 25294180

VL - 19

SP - 1515

EP - 1519

JO - Tropical Medicine & International Health

JF - Tropical Medicine & International Health

SN - 1360-2276

IS - 12

ER -

ID: 127225170