Outstanding challenges for rotavirus vaccine introduction in low-income countries - a systematic review
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Outstanding challenges for rotavirus vaccine introduction in low-income countries - a systematic review. / Ustrup, Marte; Madsen, Lizell B.; Bygbjerg, Ib C.; Konradsen, Flemming.
I: Danish Medical Bulletin, Bind 58, Nr. 10, 10.2011, s. 8.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Outstanding challenges for rotavirus vaccine introduction in low-income countries - a systematic review
AU - Ustrup, Marte
AU - Madsen, Lizell B.
AU - Bygbjerg, Ib C.
AU - Konradsen, Flemming
PY - 2011/10
Y1 - 2011/10
N2 - Rotavirus infections are the most common cause of severe diarrhoea in children worldwide. Two internationally licensed rotavirus vaccines have proven to be efficacious in middle- and high-income countries and they could potentially be valuable tools for the prevention of rotavirusassociated diarrhoea in low-income countries where the disease burden is greatest. However, before the vaccines can be introduced into the national immunisation programmes in these countries, many challenges related to the financing of vaccine purchase, the cold chain capacity and vaccine efficacy must be overcome. There is also a need for political commitment to prevent rotavirus infections as well as a need for an overall strengthening of the health systems in low-income countries. If these challenges were met, rotavirus vaccination could substantially improve child health and survival from rotavirusassociated diarrhoea.
AB - Rotavirus infections are the most common cause of severe diarrhoea in children worldwide. Two internationally licensed rotavirus vaccines have proven to be efficacious in middle- and high-income countries and they could potentially be valuable tools for the prevention of rotavirusassociated diarrhoea in low-income countries where the disease burden is greatest. However, before the vaccines can be introduced into the national immunisation programmes in these countries, many challenges related to the financing of vaccine purchase, the cold chain capacity and vaccine efficacy must be overcome. There is also a need for political commitment to prevent rotavirus infections as well as a need for an overall strengthening of the health systems in low-income countries. If these challenges were met, rotavirus vaccination could substantially improve child health and survival from rotavirusassociated diarrhoea.
UR - http://www.scopus.com/inward/record.url?scp=80053611042&partnerID=8YFLogxK
M3 - Journal article
AN - SCOPUS:80053611042
VL - 58
SP - 8
JO - Danish Medical Journal
JF - Danish Medical Journal
SN - 2245-1919
IS - 10
ER -
ID: 157044791