Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data

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Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging : a pooled analysis of individual patient data. / Garcia Castillo, Elena; Alonso Perez, Tamara; Ancochea, Julio; Pastor Sanz, Maria Teresa; Almagro, Pere; Martinez-Camblor, Pablo; Miravitlles, Marc; Rodriguez-Carballeira, Monica; Navarro, Annie; Lamprecht, Bernd; Ramirez-Garcia Luna, Ana S.; Kaiser, Bernhard; Alfageme, Inmaculada; Casanova, Ciro; Esteban, Cristobal; Soler-Cataluna, Juan J.; de-Torres, Juan P.; Celli, Bartolome R.; Marin, Jose M.; ter Riet, Gerben; Sobradillo, Patricia; Lange, Peter; Garcia-Aymerich, Judith; Anto, Josep M.; Turner, Alice M.; Han, MeiLan K.; Langhammer, Arnulf; Vikjord, Sigrid Anna Aalberg; Sternberg, Alice; Leivseth, Linda; Bakke, Per; Johannessen, Ane; Oga, Toru; Cosio, Borja G.; Echazarreta, Andres; Roche, Nicolas; Burgel, Pierre-Regis; Sin, Don D.; Puhan, Milo A.; Luis Lopez-Campos, Jose; Carrasco, Laura; Soriano, Joan B.; 3CIA Collaboration.

I: ERJ Open Research, Bind 6, Nr. 4, ARTN 00253-2020, 2020.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Garcia Castillo, E, Alonso Perez, T, Ancochea, J, Pastor Sanz, MT, Almagro, P, Martinez-Camblor, P, Miravitlles, M, Rodriguez-Carballeira, M, Navarro, A, Lamprecht, B, Ramirez-Garcia Luna, AS, Kaiser, B, Alfageme, I, Casanova, C, Esteban, C, Soler-Cataluna, JJ, de-Torres, JP, Celli, BR, Marin, JM, ter Riet, G, Sobradillo, P, Lange, P, Garcia-Aymerich, J, Anto, JM, Turner, AM, Han, MK, Langhammer, A, Vikjord, SAA, Sternberg, A, Leivseth, L, Bakke, P, Johannessen, A, Oga, T, Cosio, BG, Echazarreta, A, Roche, N, Burgel, P-R, Sin, DD, Puhan, MA, Luis Lopez-Campos, J, Carrasco, L, Soriano, JB & 3CIA Collaboration 2020, 'Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data', ERJ Open Research, bind 6, nr. 4, ARTN 00253-2020. https://doi.org/10.1183/23120541.00253-2020

APA

Garcia Castillo, E., Alonso Perez, T., Ancochea, J., Pastor Sanz, M. T., Almagro, P., Martinez-Camblor, P., Miravitlles, M., Rodriguez-Carballeira, M., Navarro, A., Lamprecht, B., Ramirez-Garcia Luna, A. S., Kaiser, B., Alfageme, I., Casanova, C., Esteban, C., Soler-Cataluna, J. J., de-Torres, J. P., Celli, B. R., Marin, J. M., ... 3CIA Collaboration (2020). Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data. ERJ Open Research, 6(4), [ARTN 00253-2020]. https://doi.org/10.1183/23120541.00253-2020

Vancouver

Garcia Castillo E, Alonso Perez T, Ancochea J, Pastor Sanz MT, Almagro P, Martinez-Camblor P o.a. Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data. ERJ Open Research. 2020;6(4). ARTN 00253-2020. https://doi.org/10.1183/23120541.00253-2020

Author

Garcia Castillo, Elena ; Alonso Perez, Tamara ; Ancochea, Julio ; Pastor Sanz, Maria Teresa ; Almagro, Pere ; Martinez-Camblor, Pablo ; Miravitlles, Marc ; Rodriguez-Carballeira, Monica ; Navarro, Annie ; Lamprecht, Bernd ; Ramirez-Garcia Luna, Ana S. ; Kaiser, Bernhard ; Alfageme, Inmaculada ; Casanova, Ciro ; Esteban, Cristobal ; Soler-Cataluna, Juan J. ; de-Torres, Juan P. ; Celli, Bartolome R. ; Marin, Jose M. ; ter Riet, Gerben ; Sobradillo, Patricia ; Lange, Peter ; Garcia-Aymerich, Judith ; Anto, Josep M. ; Turner, Alice M. ; Han, MeiLan K. ; Langhammer, Arnulf ; Vikjord, Sigrid Anna Aalberg ; Sternberg, Alice ; Leivseth, Linda ; Bakke, Per ; Johannessen, Ane ; Oga, Toru ; Cosio, Borja G. ; Echazarreta, Andres ; Roche, Nicolas ; Burgel, Pierre-Regis ; Sin, Don D. ; Puhan, Milo A. ; Luis Lopez-Campos, Jose ; Carrasco, Laura ; Soriano, Joan B. ; 3CIA Collaboration. / Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging : a pooled analysis of individual patient data. I: ERJ Open Research. 2020 ; Bind 6, Nr. 4.

Bibtex

@article{c92dfbcbd1d5440da4e3acb790b60fd6,
title = "Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data",
abstract = "In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A-4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and 2019 COPD GOLD staging systems.We studied 17 139 COPD patients from the 3CIA study, selecting those with complete data. Patients were classified by the 2015 and 2019 GOLD ABCD systems, and we compared the predictive ability for 5-year mortality of both classifications.In total, 17139 patients with COPD were enrolled in 22 cohorts from 11 countries between 2003 and 2017; 8823 of them had complete data and were analysed. Mean +/- SD age was 63.9 +/- 9.8 years and 62.9% were male. GOLD 2019 classified the patients in milder degrees of COPD. For both classifications, group D had higher mortality. 5-year mortality did not differ between groups B and C in GOLD 2015; in GOLD 2019, mortality was greater for group B than C. Patients classified as group A and B had better sensitivity and positive predictive value with the GOLD 2019 classification than GOLD 2015. GOLD 2015 had better sensitivity for group C and D than GOLD 2019. The area under the curve values for 5-year mortality were only 0.67 (95% CI 0.66-0.68) for GOLD 2015 and 0.65 (95% CI 0.63-0.66) for GOLD 2019. The new GOLD 2019 classification does not predict mortality better than the previous GOLD 2015 system.",
keywords = "COPD PATIENTS, CLASSIFICATION, DISABILITY, VALIDITY, OUTCOMES, ASTHMA",
author = "{Garcia Castillo}, Elena and {Alonso Perez}, Tamara and Julio Ancochea and {Pastor Sanz}, {Maria Teresa} and Pere Almagro and Pablo Martinez-Camblor and Marc Miravitlles and Monica Rodriguez-Carballeira and Annie Navarro and Bernd Lamprecht and {Ramirez-Garcia Luna}, {Ana S.} and Bernhard Kaiser and Inmaculada Alfageme and Ciro Casanova and Cristobal Esteban and Soler-Cataluna, {Juan J.} and de-Torres, {Juan P.} and Celli, {Bartolome R.} and Marin, {Jose M.} and {ter Riet}, Gerben and Patricia Sobradillo and Peter Lange and Judith Garcia-Aymerich and Anto, {Josep M.} and Turner, {Alice M.} and Han, {MeiLan K.} and Arnulf Langhammer and Vikjord, {Sigrid Anna Aalberg} and Alice Sternberg and Linda Leivseth and Per Bakke and Ane Johannessen and Toru Oga and Cosio, {Borja G.} and Andres Echazarreta and Nicolas Roche and Pierre-Regis Burgel and Sin, {Don D.} and Puhan, {Milo A.} and {Luis Lopez-Campos}, Jose and Laura Carrasco and Soriano, {Joan B.} and {3CIA Collaboration}",
year = "2020",
doi = "10.1183/23120541.00253-2020",
language = "English",
volume = "6",
journal = "ERJ Open Research",
issn = "2312-0541",
publisher = "ERS publications",
number = "4",

}

RIS

TY - JOUR

T1 - Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging

T2 - a pooled analysis of individual patient data

AU - Garcia Castillo, Elena

AU - Alonso Perez, Tamara

AU - Ancochea, Julio

AU - Pastor Sanz, Maria Teresa

AU - Almagro, Pere

AU - Martinez-Camblor, Pablo

AU - Miravitlles, Marc

AU - Rodriguez-Carballeira, Monica

AU - Navarro, Annie

AU - Lamprecht, Bernd

AU - Ramirez-Garcia Luna, Ana S.

AU - Kaiser, Bernhard

AU - Alfageme, Inmaculada

AU - Casanova, Ciro

AU - Esteban, Cristobal

AU - Soler-Cataluna, Juan J.

AU - de-Torres, Juan P.

AU - Celli, Bartolome R.

AU - Marin, Jose M.

AU - ter Riet, Gerben

AU - Sobradillo, Patricia

AU - Lange, Peter

AU - Garcia-Aymerich, Judith

AU - Anto, Josep M.

AU - Turner, Alice M.

AU - Han, MeiLan K.

AU - Langhammer, Arnulf

AU - Vikjord, Sigrid Anna Aalberg

AU - Sternberg, Alice

AU - Leivseth, Linda

AU - Bakke, Per

AU - Johannessen, Ane

AU - Oga, Toru

AU - Cosio, Borja G.

AU - Echazarreta, Andres

AU - Roche, Nicolas

AU - Burgel, Pierre-Regis

AU - Sin, Don D.

AU - Puhan, Milo A.

AU - Luis Lopez-Campos, Jose

AU - Carrasco, Laura

AU - Soriano, Joan B.

AU - 3CIA Collaboration

PY - 2020

Y1 - 2020

N2 - In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A-4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and 2019 COPD GOLD staging systems.We studied 17 139 COPD patients from the 3CIA study, selecting those with complete data. Patients were classified by the 2015 and 2019 GOLD ABCD systems, and we compared the predictive ability for 5-year mortality of both classifications.In total, 17139 patients with COPD were enrolled in 22 cohorts from 11 countries between 2003 and 2017; 8823 of them had complete data and were analysed. Mean +/- SD age was 63.9 +/- 9.8 years and 62.9% were male. GOLD 2019 classified the patients in milder degrees of COPD. For both classifications, group D had higher mortality. 5-year mortality did not differ between groups B and C in GOLD 2015; in GOLD 2019, mortality was greater for group B than C. Patients classified as group A and B had better sensitivity and positive predictive value with the GOLD 2019 classification than GOLD 2015. GOLD 2015 had better sensitivity for group C and D than GOLD 2019. The area under the curve values for 5-year mortality were only 0.67 (95% CI 0.66-0.68) for GOLD 2015 and 0.65 (95% CI 0.63-0.66) for GOLD 2019. The new GOLD 2019 classification does not predict mortality better than the previous GOLD 2015 system.

AB - In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A-4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and 2019 COPD GOLD staging systems.We studied 17 139 COPD patients from the 3CIA study, selecting those with complete data. Patients were classified by the 2015 and 2019 GOLD ABCD systems, and we compared the predictive ability for 5-year mortality of both classifications.In total, 17139 patients with COPD were enrolled in 22 cohorts from 11 countries between 2003 and 2017; 8823 of them had complete data and were analysed. Mean +/- SD age was 63.9 +/- 9.8 years and 62.9% were male. GOLD 2019 classified the patients in milder degrees of COPD. For both classifications, group D had higher mortality. 5-year mortality did not differ between groups B and C in GOLD 2015; in GOLD 2019, mortality was greater for group B than C. Patients classified as group A and B had better sensitivity and positive predictive value with the GOLD 2019 classification than GOLD 2015. GOLD 2015 had better sensitivity for group C and D than GOLD 2019. The area under the curve values for 5-year mortality were only 0.67 (95% CI 0.66-0.68) for GOLD 2015 and 0.65 (95% CI 0.63-0.66) for GOLD 2019. The new GOLD 2019 classification does not predict mortality better than the previous GOLD 2015 system.

KW - COPD PATIENTS

KW - CLASSIFICATION

KW - DISABILITY

KW - VALIDITY

KW - OUTCOMES

KW - ASTHMA

U2 - 10.1183/23120541.00253-2020

DO - 10.1183/23120541.00253-2020

M3 - Journal article

C2 - 33263033

VL - 6

JO - ERJ Open Research

JF - ERJ Open Research

SN - 2312-0541

IS - 4

M1 - ARTN 00253-2020

ER -

ID: 255501530