Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau

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Standard

Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau. / Hansen, Olga Bengård; Rodrigues, Amabelia; Martins, Cesario; Rieckmann, Andreas; Benn, Christine Stabell; Aaby, Peter; Fisker, Ane Bærent.

I: Journal of Tropical Pediatrics, Bind 65, Nr. 5, 2019, s. 446-456.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hansen, OB, Rodrigues, A, Martins, C, Rieckmann, A, Benn, CS, Aaby, P & Fisker, AB 2019, 'Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau', Journal of Tropical Pediatrics, bind 65, nr. 5, s. 446-456. https://doi.org/10.1093/tropej/fmy075

APA

Hansen, O. B., Rodrigues, A., Martins, C., Rieckmann, A., Benn, C. S., Aaby, P., & Fisker, A. B. (2019). Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau. Journal of Tropical Pediatrics, 65(5), 446-456. https://doi.org/10.1093/tropej/fmy075

Vancouver

Hansen OB, Rodrigues A, Martins C, Rieckmann A, Benn CS, Aaby P o.a. Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau. Journal of Tropical Pediatrics. 2019;65(5):446-456. https://doi.org/10.1093/tropej/fmy075

Author

Hansen, Olga Bengård ; Rodrigues, Amabelia ; Martins, Cesario ; Rieckmann, Andreas ; Benn, Christine Stabell ; Aaby, Peter ; Fisker, Ane Bærent. / Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau. I: Journal of Tropical Pediatrics. 2019 ; Bind 65, Nr. 5. s. 446-456.

Bibtex

@article{d1e7ad36610f4592bf2f2d396e7ce510,
title = "Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau",
abstract = "Background: In addition to vaccines' specific effects, vaccines may have non-specific effects (NSEs) altering the susceptibility to unrelated infections. Non-live vaccines have been associated with negative NSEs. In 2010, a campaign with the non-live H1N1-influenza vaccine targeted children 6-59 months in Guinea-Bissau.Methods: Bandim Health Project runs a health and demographic surveillance system site in Guinea-Bissau. Using a Cox proportional hazards model, we compared all-cause consultation rates after vs. before the campaign, stratified by participation status.Results: Among 10 290 children eligible for the campaign, 60% had participated, 18% had not and for 22% no information was obtained. After the H1N1 campaign, the consultation rates tended to decline more for participants [HR = 0.80 (95% confidence interval, CI: 0.75; 0.85)] than for non-participants [HR = 0.68 (95% CI: 0.58; 0.79)], p = 0.06 for same effect.Conclusion: The decline in the vaccinated group may have been smaller than the decline in the non-vaccinated group consistent with H1N1-vaccine increasing susceptibility to unrelated infections.",
author = "Hansen, {Olga Beng{\aa}rd} and Amabelia Rodrigues and Cesario Martins and Andreas Rieckmann and Benn, {Christine Stabell} and Peter Aaby and Fisker, {Ane B{\ae}rent}",
note = "A correction has been published: Journal of Tropical Pediatrics, fmz009, https://doi.org/10.1093/tropej/fmz009 ",
year = "2019",
doi = "10.1093/tropej/fmy075",
language = "English",
volume = "65",
pages = "446--456",
journal = "Journal of Tropical Pediatrics",
issn = "0142-6338",
publisher = "Oxford University Press",
number = "5",

}

RIS

TY - JOUR

T1 - Impact of H1N1 Influenza Vaccination on Child Morbidity in Guinea-Bissau

AU - Hansen, Olga Bengård

AU - Rodrigues, Amabelia

AU - Martins, Cesario

AU - Rieckmann, Andreas

AU - Benn, Christine Stabell

AU - Aaby, Peter

AU - Fisker, Ane Bærent

N1 - A correction has been published: Journal of Tropical Pediatrics, fmz009, https://doi.org/10.1093/tropej/fmz009

PY - 2019

Y1 - 2019

N2 - Background: In addition to vaccines' specific effects, vaccines may have non-specific effects (NSEs) altering the susceptibility to unrelated infections. Non-live vaccines have been associated with negative NSEs. In 2010, a campaign with the non-live H1N1-influenza vaccine targeted children 6-59 months in Guinea-Bissau.Methods: Bandim Health Project runs a health and demographic surveillance system site in Guinea-Bissau. Using a Cox proportional hazards model, we compared all-cause consultation rates after vs. before the campaign, stratified by participation status.Results: Among 10 290 children eligible for the campaign, 60% had participated, 18% had not and for 22% no information was obtained. After the H1N1 campaign, the consultation rates tended to decline more for participants [HR = 0.80 (95% confidence interval, CI: 0.75; 0.85)] than for non-participants [HR = 0.68 (95% CI: 0.58; 0.79)], p = 0.06 for same effect.Conclusion: The decline in the vaccinated group may have been smaller than the decline in the non-vaccinated group consistent with H1N1-vaccine increasing susceptibility to unrelated infections.

AB - Background: In addition to vaccines' specific effects, vaccines may have non-specific effects (NSEs) altering the susceptibility to unrelated infections. Non-live vaccines have been associated with negative NSEs. In 2010, a campaign with the non-live H1N1-influenza vaccine targeted children 6-59 months in Guinea-Bissau.Methods: Bandim Health Project runs a health and demographic surveillance system site in Guinea-Bissau. Using a Cox proportional hazards model, we compared all-cause consultation rates after vs. before the campaign, stratified by participation status.Results: Among 10 290 children eligible for the campaign, 60% had participated, 18% had not and for 22% no information was obtained. After the H1N1 campaign, the consultation rates tended to decline more for participants [HR = 0.80 (95% confidence interval, CI: 0.75; 0.85)] than for non-participants [HR = 0.68 (95% CI: 0.58; 0.79)], p = 0.06 for same effect.Conclusion: The decline in the vaccinated group may have been smaller than the decline in the non-vaccinated group consistent with H1N1-vaccine increasing susceptibility to unrelated infections.

U2 - 10.1093/tropej/fmy075

DO - 10.1093/tropej/fmy075

M3 - Journal article

C2 - 30590828

VL - 65

SP - 446

EP - 456

JO - Journal of Tropical Pediatrics

JF - Journal of Tropical Pediatrics

SN - 0142-6338

IS - 5

ER -

ID: 218515964