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ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination. / Søndergaard, Elisabeth; Rauch, Alexander; Michaut, Magali; Rapin, Nicolas; Rehn, Matilda; Wilhelmson, Anna S.; Camponeschi, Alessandro; Hasemann, Marie S.; Bagger, Frederik O.; Jendholm, Johan; Knudsen, Kasper J.; Mandrup, Susanne; Mårtensson, Inga Lill; Porse, Bo T.
I:
Cell Reports, Bind 29, Nr. 9, 26.11.2019, s. 2756-2769.e6.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Søndergaard, E, Rauch, A
, Michaut, M, Rapin, N, Rehn, M
, Wilhelmson, AS, Camponeschi, A, Hasemann, MS, Bagger, FO, Jendholm, J, Knudsen, KJ, Mandrup, S, Mårtensson, IL
& Porse, BT 2019, '
ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination',
Cell Reports, bind 29, nr. 9, s. 2756-2769.e6.
https://doi.org/10.1016/j.celrep.2019.10.098APA
Søndergaard, E., Rauch, A.
, Michaut, M., Rapin, N., Rehn, M.
, Wilhelmson, A. S., Camponeschi, A., Hasemann, M. S., Bagger, F. O., Jendholm, J., Knudsen, K. J., Mandrup, S., Mårtensson, I. L.
, & Porse, B. T. (2019).
ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination.
Cell Reports,
29(9), 2756-2769.e6.
https://doi.org/10.1016/j.celrep.2019.10.098Vancouver
Søndergaard E, Rauch A
, Michaut M, Rapin N, Rehn M
, Wilhelmson AS o.a.
ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination.
Cell Reports. 2019 nov. 26;29(9):2756-2769.e6.
https://doi.org/10.1016/j.celrep.2019.10.098Author
Søndergaard, Elisabeth ; Rauch, Alexander ; Michaut, Magali ; Rapin, Nicolas ; Rehn, Matilda ; Wilhelmson, Anna S. ; Camponeschi, Alessandro ; Hasemann, Marie S. ; Bagger, Frederik O. ; Jendholm, Johan ; Knudsen, Kasper J. ; Mandrup, Susanne ; Mårtensson, Inga Lill ; Porse, Bo T. / ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination. I: Cell Reports. 2019 ; Bind 29, Nr. 9. s. 2756-2769.e6.
Bibtex
@article{f9c82e371773444092db18481db881d1,
title = "ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination",
abstract = "S{\o}ndergaard et al. demonstrate that ERG is a critical transcriptional regulator essential for B cell development. Loss of ERG leads to a marked reduction in V-to-DJ recombination at the Igh locus, precluding B cell progenitors from expressing the pre-B cell receptor, which is required for entering the final stages of B cell development.",
keywords = "B cell development, ERG, ETS-related gene, immunoglobulin heavy-chain gene, pre-BCR, transcriptional control, V(D)J recombination",
author = "Elisabeth S{\o}ndergaard and Alexander Rauch and Magali Michaut and Nicolas Rapin and Matilda Rehn and Wilhelmson, {Anna S.} and Alessandro Camponeschi and Hasemann, {Marie S.} and Bagger, {Frederik O.} and Johan Jendholm and Knudsen, {Kasper J.} and Susanne Mandrup and M{\aa}rtensson, {Inga Lill} and Porse, {Bo T.}",
year = "2019",
month = nov,
day = "26",
doi = "10.1016/j.celrep.2019.10.098",
language = "English",
volume = "29",
pages = "2756--2769.e6",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "9",
}
RIS
TY - JOUR
T1 - ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination
AU - Søndergaard, Elisabeth
AU - Rauch, Alexander
AU - Michaut, Magali
AU - Rapin, Nicolas
AU - Rehn, Matilda
AU - Wilhelmson, Anna S.
AU - Camponeschi, Alessandro
AU - Hasemann, Marie S.
AU - Bagger, Frederik O.
AU - Jendholm, Johan
AU - Knudsen, Kasper J.
AU - Mandrup, Susanne
AU - Mårtensson, Inga Lill
AU - Porse, Bo T.
PY - 2019/11/26
Y1 - 2019/11/26
N2 - Søndergaard et al. demonstrate that ERG is a critical transcriptional regulator essential for B cell development. Loss of ERG leads to a marked reduction in V-to-DJ recombination at the Igh locus, precluding B cell progenitors from expressing the pre-B cell receptor, which is required for entering the final stages of B cell development.
AB - Søndergaard et al. demonstrate that ERG is a critical transcriptional regulator essential for B cell development. Loss of ERG leads to a marked reduction in V-to-DJ recombination at the Igh locus, precluding B cell progenitors from expressing the pre-B cell receptor, which is required for entering the final stages of B cell development.
KW - B cell development
KW - ERG
KW - ETS-related gene
KW - immunoglobulin heavy-chain gene
KW - pre-BCR
KW - transcriptional control
KW - V(D)J recombination
U2 - 10.1016/j.celrep.2019.10.098
DO - 10.1016/j.celrep.2019.10.098
M3 - Journal article
C2 - 31775043
AN - SCOPUS:85075512481
VL - 29
SP - 2756-2769.e6
JO - Cell Reports
JF - Cell Reports
SN - 2211-1247
IS - 9
ER -
