Equipercentile equating of scores from common patient-reported outcome measures of physical function in patients with cancer

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Maria Rothmund
  • Micha J Pilz
  • Lisa Schlosser
  • Juan I Arraras
  • Grønvold, Mogens
  • Bernhard Holzner
  • Marieke van Leeuwen
  • Morten Aa Petersen
  • Heike Schmidt
  • Teresa Young
  • Matthias Rose
  • David Cella
  • Johannes M Giesinger
  • EORTC Quality of Life Group

OBJECTIVE: To provide equipercentile equating of physical function (PF) scores from frequently used PROMs in cancer patients to facilitate data pooling and comparisons.

STUDY DESIGN AND SETTING: Adult cancer patients from five European countries completed the EORTC CAT Core, EORTC QLQ-C30, FACT-G, SF-36, and the PROMIS Physical Function 20a short form. The R package "equate" was used to establish conversion tables of PF scores on those measures with a bivariate rank correlation of at least 0.75.

RESULTS: In total, 953 patients with cancer (mean age 58.9 years, 54.7% men) participated. Bivariate rank correlations between PF scores from the EORTC CAT Core, EORTC QLQ-C30, SF-36, and PROMIS were all above 0.85, but below 0.69 for the FACT-G. Conversion tables were established for all measures but the FACT-G. These tables indicate which score from one PROM best matches the score from another PROM and provide standard errors of converted scores.

CONCLUSION: Our analysis indicates that linking of PF scores from both EORTC measures (CAT and QLQ-C30) with PROMIS and SF-36 is possible whereas the physical domain of the FACT-G seems to be different. The established conversion tables may be used for comparing results or pooling data from clinical studies using different PROMs.

OriginalsprogEngelsk
Artikelnummer111203
TidsskriftJournal of Clinical Epidemiology
Vol/bind165
Antal sider12
ISSN0895-4356
DOI
StatusUdgivet - 2024

Bibliografisk note

Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.

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