Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America

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Standard

Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America. / Cordoba, Gloria; Caballero, Lidia; Sandholdt, Håkon; Arteaga, Fátima; Olinisky, Monica; Ruschel, Luis Fabián; Makela, Marjukka; Bjerrum, Lars.

I: Journal of Antimicrobial Chemotherapy, Bind 72, Nr. 1, 01.2017, s. 305–310.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Cordoba, G, Caballero, L, Sandholdt, H, Arteaga, F, Olinisky, M, Ruschel, LF, Makela, M & Bjerrum, L 2017, 'Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America', Journal of Antimicrobial Chemotherapy, bind 72, nr. 1, s. 305–310. https://doi.org/10.1093/jac/dkw370

APA

Cordoba, G., Caballero, L., Sandholdt, H., Arteaga, F., Olinisky, M., Ruschel, L. F., Makela, M., & Bjerrum, L. (2017). Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America. Journal of Antimicrobial Chemotherapy, 72(1), 305–310. https://doi.org/10.1093/jac/dkw370

Vancouver

Cordoba G, Caballero L, Sandholdt H, Arteaga F, Olinisky M, Ruschel LF o.a. Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America. Journal of Antimicrobial Chemotherapy. 2017 jan;72(1):305–310. https://doi.org/10.1093/jac/dkw370

Author

Cordoba, Gloria ; Caballero, Lidia ; Sandholdt, Håkon ; Arteaga, Fátima ; Olinisky, Monica ; Ruschel, Luis Fabián ; Makela, Marjukka ; Bjerrum, Lars. / Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America. I: Journal of Antimicrobial Chemotherapy. 2017 ; Bind 72, Nr. 1. s. 305–310.

Bibtex

@article{a90215400f5b4cdf9c6effb82e4f68da,
title = "Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America",
abstract = "OBJECTIVES: To describe and compare antibiotic prescribing patterns for primary care patients with respiratory tract infections (RTIs) in four South American countries.METHODS: This was a prospective observational study. General practitioners (GPs) from Argentina, Bolivia, Paraguay and Uruguay registered data about all consultations of patients with suspected RTIs in the winter of 2014 (June-August). Variation in antibiotic prescriptions was assessed using a two-level hierarchical logistic model.RESULTS: Participating GPs (n = 171) registered 11 446 patients with suspected RTI; 3701 (33%) of these received an antibiotic prescription. There was a wide variation across countries in the use and selection of antibiotics. For example, 94% of patients with acute bronchitis were prescribed antibiotics in Bolivia, while in Uruguay only 21% received antibiotics. Amoxicillin was the most commonly prescribed antibiotic across countries, but prescription rates varied between 45% in Bolivia and 69% in Uruguay. Compared with the overall mean prescribing rate, and after adjusting for clinical presentation and demographics, prescribing of antibiotics varied by a factor of 6, the OR ranging from 0.37 (95% CI = 0.21-0.65) in Uruguay to 2.58 (95% CI = 1.66-4) in Bolivia.CONCLUSIONS: The large variation in use and selection of antibiotics across countries is not explained by different patient populations. It could be explained by diagnostic uncertainty and contextual characteristics beyond clinical practice. Reducing uncertainty and country variation requires greater support from the healthcare systems by providing GPs with evidence-based guidelines and tools to apply them.",
author = "Gloria Cordoba and Lidia Caballero and H{\aa}kon Sandholdt and F{\'a}tima Arteaga and Monica Olinisky and Ruschel, {Luis Fabi{\'a}n} and Marjukka Makela and Lars Bjerrum",
note = "{\textcopyright} The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.",
year = "2017",
month = jan,
doi = "10.1093/jac/dkw370",
language = "English",
volume = "72",
pages = "305–310",
journal = "Journal of Antimicrobial Chemotherapy",
issn = "0305-7453",
publisher = "Oxford University Press",
number = "1",

}

RIS

TY - JOUR

T1 - Antibiotic prescriptions for suspected respiratory tract infection in primary care in South America

AU - Cordoba, Gloria

AU - Caballero, Lidia

AU - Sandholdt, Håkon

AU - Arteaga, Fátima

AU - Olinisky, Monica

AU - Ruschel, Luis Fabián

AU - Makela, Marjukka

AU - Bjerrum, Lars

N1 - © The Author 2016. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

PY - 2017/1

Y1 - 2017/1

N2 - OBJECTIVES: To describe and compare antibiotic prescribing patterns for primary care patients with respiratory tract infections (RTIs) in four South American countries.METHODS: This was a prospective observational study. General practitioners (GPs) from Argentina, Bolivia, Paraguay and Uruguay registered data about all consultations of patients with suspected RTIs in the winter of 2014 (June-August). Variation in antibiotic prescriptions was assessed using a two-level hierarchical logistic model.RESULTS: Participating GPs (n = 171) registered 11 446 patients with suspected RTI; 3701 (33%) of these received an antibiotic prescription. There was a wide variation across countries in the use and selection of antibiotics. For example, 94% of patients with acute bronchitis were prescribed antibiotics in Bolivia, while in Uruguay only 21% received antibiotics. Amoxicillin was the most commonly prescribed antibiotic across countries, but prescription rates varied between 45% in Bolivia and 69% in Uruguay. Compared with the overall mean prescribing rate, and after adjusting for clinical presentation and demographics, prescribing of antibiotics varied by a factor of 6, the OR ranging from 0.37 (95% CI = 0.21-0.65) in Uruguay to 2.58 (95% CI = 1.66-4) in Bolivia.CONCLUSIONS: The large variation in use and selection of antibiotics across countries is not explained by different patient populations. It could be explained by diagnostic uncertainty and contextual characteristics beyond clinical practice. Reducing uncertainty and country variation requires greater support from the healthcare systems by providing GPs with evidence-based guidelines and tools to apply them.

AB - OBJECTIVES: To describe and compare antibiotic prescribing patterns for primary care patients with respiratory tract infections (RTIs) in four South American countries.METHODS: This was a prospective observational study. General practitioners (GPs) from Argentina, Bolivia, Paraguay and Uruguay registered data about all consultations of patients with suspected RTIs in the winter of 2014 (June-August). Variation in antibiotic prescriptions was assessed using a two-level hierarchical logistic model.RESULTS: Participating GPs (n = 171) registered 11 446 patients with suspected RTI; 3701 (33%) of these received an antibiotic prescription. There was a wide variation across countries in the use and selection of antibiotics. For example, 94% of patients with acute bronchitis were prescribed antibiotics in Bolivia, while in Uruguay only 21% received antibiotics. Amoxicillin was the most commonly prescribed antibiotic across countries, but prescription rates varied between 45% in Bolivia and 69% in Uruguay. Compared with the overall mean prescribing rate, and after adjusting for clinical presentation and demographics, prescribing of antibiotics varied by a factor of 6, the OR ranging from 0.37 (95% CI = 0.21-0.65) in Uruguay to 2.58 (95% CI = 1.66-4) in Bolivia.CONCLUSIONS: The large variation in use and selection of antibiotics across countries is not explained by different patient populations. It could be explained by diagnostic uncertainty and contextual characteristics beyond clinical practice. Reducing uncertainty and country variation requires greater support from the healthcare systems by providing GPs with evidence-based guidelines and tools to apply them.

U2 - 10.1093/jac/dkw370

DO - 10.1093/jac/dkw370

M3 - Journal article

C2 - 27624570

VL - 72

SP - 305

EP - 310

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

SN - 0305-7453

IS - 1

ER -

ID: 165878188