An inter-laboratory comparison for determination of cortisol in saliva

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

An inter-laboratory comparison for determination of cortisol in saliva. / Garde, Anne Helene; Hansen, Åse Marie; Nikolajsen, Thomas Block.

I: Accreditation and Quality Assurance, Bind 8, Nr. 1, 01.01.2003, s. 16-20.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Garde, AH, Hansen, ÅM & Nikolajsen, TB 2003, 'An inter-laboratory comparison for determination of cortisol in saliva', Accreditation and Quality Assurance, bind 8, nr. 1, s. 16-20. https://doi.org/10.1007/s00769-002-0548-x

APA

Garde, A. H., Hansen, Å. M., & Nikolajsen, T. B. (2003). An inter-laboratory comparison for determination of cortisol in saliva. Accreditation and Quality Assurance, 8(1), 16-20. https://doi.org/10.1007/s00769-002-0548-x

Vancouver

Garde AH, Hansen ÅM, Nikolajsen TB. An inter-laboratory comparison for determination of cortisol in saliva. Accreditation and Quality Assurance. 2003 jan. 1;8(1):16-20. https://doi.org/10.1007/s00769-002-0548-x

Author

Garde, Anne Helene ; Hansen, Åse Marie ; Nikolajsen, Thomas Block. / An inter-laboratory comparison for determination of cortisol in saliva. I: Accreditation and Quality Assurance. 2003 ; Bind 8, Nr. 1. s. 16-20.

Bibtex

@article{f184160c66a148e8909ed61ac6dabd4b,
title = "An inter-laboratory comparison for determination of cortisol in saliva",
abstract = "An inter-laboratory comparison study for cortisol in saliva is reported in the present study. Nine laboratories representing four different methods participated in the study. Each laboratory measured five blind samples prepared from natural saliva spiked with a pure certified reference material in the range 0-70 nmol/L. The average observed values were established as means of eight laboratories, because one laboratory was excluded as an outlier. The natural content of cortisol in the pooled saliva was 6.8 nmol/L. The recovery of the certified reference material was 83%-131% (164% for the outlying laboratory). For five laboratories the 95%-confidence intervals of the recoveries did not cover 100%. The standard deviations for a concentration of 10 nmol/L were estimated for each laboratory. They were 0.64-1.67 nmol/L (6.26 nmol/L for the outlying laboratory). The present study emphasizes the need for an external proficiency-testing scheme and a certified reference material for cortisol in saliva.",
keywords = "Cortisol, External quality control, Method comparison, Saliva",
author = "Garde, {Anne Helene} and Hansen, {{\AA}se Marie} and Nikolajsen, {Thomas Block}",
year = "2003",
month = jan,
day = "1",
doi = "10.1007/s00769-002-0548-x",
language = "English",
volume = "8",
pages = "16--20",
journal = "Accreditation and Quality Assurance",
issn = "0949-1775",
publisher = "Springer New York",
number = "1",

}

RIS

TY - JOUR

T1 - An inter-laboratory comparison for determination of cortisol in saliva

AU - Garde, Anne Helene

AU - Hansen, Åse Marie

AU - Nikolajsen, Thomas Block

PY - 2003/1/1

Y1 - 2003/1/1

N2 - An inter-laboratory comparison study for cortisol in saliva is reported in the present study. Nine laboratories representing four different methods participated in the study. Each laboratory measured five blind samples prepared from natural saliva spiked with a pure certified reference material in the range 0-70 nmol/L. The average observed values were established as means of eight laboratories, because one laboratory was excluded as an outlier. The natural content of cortisol in the pooled saliva was 6.8 nmol/L. The recovery of the certified reference material was 83%-131% (164% for the outlying laboratory). For five laboratories the 95%-confidence intervals of the recoveries did not cover 100%. The standard deviations for a concentration of 10 nmol/L were estimated for each laboratory. They were 0.64-1.67 nmol/L (6.26 nmol/L for the outlying laboratory). The present study emphasizes the need for an external proficiency-testing scheme and a certified reference material for cortisol in saliva.

AB - An inter-laboratory comparison study for cortisol in saliva is reported in the present study. Nine laboratories representing four different methods participated in the study. Each laboratory measured five blind samples prepared from natural saliva spiked with a pure certified reference material in the range 0-70 nmol/L. The average observed values were established as means of eight laboratories, because one laboratory was excluded as an outlier. The natural content of cortisol in the pooled saliva was 6.8 nmol/L. The recovery of the certified reference material was 83%-131% (164% for the outlying laboratory). For five laboratories the 95%-confidence intervals of the recoveries did not cover 100%. The standard deviations for a concentration of 10 nmol/L were estimated for each laboratory. They were 0.64-1.67 nmol/L (6.26 nmol/L for the outlying laboratory). The present study emphasizes the need for an external proficiency-testing scheme and a certified reference material for cortisol in saliva.

KW - Cortisol

KW - External quality control

KW - Method comparison

KW - Saliva

UR - http://www.scopus.com/inward/record.url?scp=0038543340&partnerID=8YFLogxK

U2 - 10.1007/s00769-002-0548-x

DO - 10.1007/s00769-002-0548-x

M3 - Journal article

AN - SCOPUS:0038543340

VL - 8

SP - 16

EP - 20

JO - Accreditation and Quality Assurance

JF - Accreditation and Quality Assurance

SN - 0949-1775

IS - 1

ER -

ID: 199724040