Air Pollution and Nonmalignant Respiratory Mortality in 16 Cohorts within the ESCAPE Project
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Air Pollution and Nonmalignant Respiratory Mortality in 16 Cohorts within the ESCAPE Project. / Dimakopoulou, Konstantina; Samoli, Evangelia; Beelen, Rob; Stafoggia, Massimo; Andersen, Zorana Jovanovic; Hoffmann, Barbara; Fischer, Paul; Nieuwenhuijsen, Mark; Vineis, Paolo; Xun, Wei; Hoek, Gerard; Raaschou-Nielsen, Ole; Oudin, Anna; Forsberg, Bertil; Modig, Lars; Jousilahti, Pekka; Lanki, Timo; Turunen, Anu; Oftedal, Bente; Nafstad, Per; Schwarze, Per E; Penell, Johanna; Fratiglioni, Laura; Andersson, Niklas; Pedersen, Nancy; Korek, Michal; De Faire, Ulf; Thorup Eriksen, Kirsten; Tjønneland, Anne; Becker, Thomas; Wang, Meng; Bueno-de-Mesquita, Bas; Tsai, Ming-Yi; Eeftens, Marloes; Peeters, Petra H; Meliefste, Kees; Marcon, Alessandro; Krämer, Ursula; Kuhlbusch, Thomas Aj; Vossoughi, Mohammad; Key, Timothy; de Hoogh, Kees; Hampel, Regina; Peters, Annette; Heinrich, Joachim; Weinmayr, Gudrun; Concin, Hans; Nagel, Gabriele; Ineichen, Alex; Jacquemin, Bénédicte; Stempfelet, Morgane; Vilier, Alice; Ricceri, Fulvio; Sacerdote, Carlotta; Pedeli, Xanthi; Katsoulis, Michalis; Trichopoulou, Antonia; Brunekreef, Bert; Katsouyanni, Klea.
I: American Journal of Respiratory and Critical Care Medicine, Bind 189, Nr. 6, 15.03.2014, s. 684-696.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Air Pollution and Nonmalignant Respiratory Mortality in 16 Cohorts within the ESCAPE Project
AU - Dimakopoulou, Konstantina
AU - Samoli, Evangelia
AU - Beelen, Rob
AU - Stafoggia, Massimo
AU - Andersen, Zorana Jovanovic
AU - Hoffmann, Barbara
AU - Fischer, Paul
AU - Nieuwenhuijsen, Mark
AU - Vineis, Paolo
AU - Xun, Wei
AU - Hoek, Gerard
AU - Raaschou-Nielsen, Ole
AU - Oudin, Anna
AU - Forsberg, Bertil
AU - Modig, Lars
AU - Jousilahti, Pekka
AU - Lanki, Timo
AU - Turunen, Anu
AU - Oftedal, Bente
AU - Nafstad, Per
AU - Schwarze, Per E
AU - Penell, Johanna
AU - Fratiglioni, Laura
AU - Andersson, Niklas
AU - Pedersen, Nancy
AU - Korek, Michal
AU - De Faire, Ulf
AU - Thorup Eriksen, Kirsten
AU - Tjønneland, Anne
AU - Becker, Thomas
AU - Wang, Meng
AU - Bueno-de-Mesquita, Bas
AU - Tsai, Ming-Yi
AU - Eeftens, Marloes
AU - Peeters, Petra H
AU - Meliefste, Kees
AU - Marcon, Alessandro
AU - Krämer, Ursula
AU - Kuhlbusch, Thomas Aj
AU - Vossoughi, Mohammad
AU - Key, Timothy
AU - de Hoogh, Kees
AU - Hampel, Regina
AU - Peters, Annette
AU - Heinrich, Joachim
AU - Weinmayr, Gudrun
AU - Concin, Hans
AU - Nagel, Gabriele
AU - Ineichen, Alex
AU - Jacquemin, Bénédicte
AU - Stempfelet, Morgane
AU - Vilier, Alice
AU - Ricceri, Fulvio
AU - Sacerdote, Carlotta
AU - Pedeli, Xanthi
AU - Katsoulis, Michalis
AU - Trichopoulou, Antonia
AU - Brunekreef, Bert
AU - Katsouyanni, Klea
PY - 2014/3/15
Y1 - 2014/3/15
N2 - Rationale: Prospective cohort studies have shown that chronic exposure to particulate matter and traffic related air pollution is associated with reduced survival. However, the effects on non-malignant respiratory mortality are less studied and those reported are less consistent. Objectives: We have investigated the relationship of long-term exposure to air pollution and non-malignant respiratory mortality in 16 cohorts with individual level data within the multi center European Study of Cohorts for Air Pollution Effects (ESCAPE). Methods: Data from 16 ongoing cohort studies from Europe were used. The total number of subjects was 307,553. There were 1,559 respiratory deaths during follow-up. Measurements: Air pollution exposure was estimated by land use regression models at the baseline residential addresses of study participants and traffic-proximity variables were derived from geographical databases, following a standardized procedure within ESCAPE study. Cohort-specific hazard ratios obtained by Cox proportional hazard models from standardized individual cohort analyses were combined using meta-analyses. Main Results: We found no significant associations between air pollution exposure and non-malignant respiratory mortality. Most hazard ratios were slightly below unity, with the exception of the traffic-proximity indicators. Conclusions: In this study of 16 cohorts there was no association between air pollution exposure and non malignant respiratory mortality.
AB - Rationale: Prospective cohort studies have shown that chronic exposure to particulate matter and traffic related air pollution is associated with reduced survival. However, the effects on non-malignant respiratory mortality are less studied and those reported are less consistent. Objectives: We have investigated the relationship of long-term exposure to air pollution and non-malignant respiratory mortality in 16 cohorts with individual level data within the multi center European Study of Cohorts for Air Pollution Effects (ESCAPE). Methods: Data from 16 ongoing cohort studies from Europe were used. The total number of subjects was 307,553. There were 1,559 respiratory deaths during follow-up. Measurements: Air pollution exposure was estimated by land use regression models at the baseline residential addresses of study participants and traffic-proximity variables were derived from geographical databases, following a standardized procedure within ESCAPE study. Cohort-specific hazard ratios obtained by Cox proportional hazard models from standardized individual cohort analyses were combined using meta-analyses. Main Results: We found no significant associations between air pollution exposure and non-malignant respiratory mortality. Most hazard ratios were slightly below unity, with the exception of the traffic-proximity indicators. Conclusions: In this study of 16 cohorts there was no association between air pollution exposure and non malignant respiratory mortality.
U2 - 10.1164/rccm.201310-1777OC
DO - 10.1164/rccm.201310-1777OC
M3 - Journal article
C2 - 24521254
VL - 189
SP - 684
EP - 696
JO - American Journal of Respiratory and Critical Care Medicine
JF - American Journal of Respiratory and Critical Care Medicine
SN - 1073-449X
IS - 6
ER -
ID: 101683162