Theis Lange

Theis Lange

Head of Department, Professor


  1. 2023
  2. Published

    Marginal structural models with monotonicity constraints: A case study in out-of-hospital cardiac arrest patients

    Starkopf, L., Rajan, S., Lange, Theis & Gerds, Thomas Alexander, 2023, In: Statistics in Medicine. 42, 5, p. 603-618 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Platform trials: Platformsforsøg

    Perner, A., Kjær, M. B. N., Thorsen-Meyer, H. C., Kaas-Hansen, B. S., Munch, M. W., Collet, M. O., Bruun, C. R., Jensen, A. K., Lange, T., Albertsen, T., Pedersen, C. D., Poulsen, L. M., Mathiesen, O., Brøchner, A. C., Strøm, T., Andersen, L. W., Christensen, S., Rasmussen, B. S., Schjørring, O. L., Maagaard, M. & 2 others, Møller, Morten Hylander & Granholm, A., 2023, In: Ugeskrift for Laeger. 185, 41, 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Real-world causal evidence for planned predictive enrichment in critical care trials: A scoping review

    Kaas-Hansen, Benjamin Skov, Granholm, A., Sivapalan, P., Anthon, C. T., Schjørring, O. L., Maagaard, M., Kjaer, M. N., Mølgaard, J., Ellekjaer, K. L., Fagerberg, S. K., Lange, Theis, Møller, Morten Hylander & Perner, Anders, 2023, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 16-25 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    The impact of modifiable risk factors in the association between socioeconomic status and sudden cardiac death in a prospective cohort study: equal access to healthcare, unequal outcome

    Warming, P. E., Ågesen, F. N., Lynge, T. H., Garcia, R., Banner, Jytte, Prescott, Eva, Lange, Theis, Jabbari, R. & Tfelt-Hansen, Jacob, 2023, In: European Journal of Preventive Cardiology. 30, 14, p. 1526–1534 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Traumatic brain injury, stroke, and epilepsy: A mediation study in a Danish nationwide cohort

    Lolk, K., Lange, Theis, Elwert, F., Dreier, J. W. & Christensen, J., 2023, In: Epilepsia. 64, 3, p. 718-727 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Use of days alive without life support and similar count outcomes in randomised clinical trials – an overview and comparison of methodological choices and analysis methods

    Granholm, A., Kaas-Hansen, Benjamin Skov, Lange, Theis, Munch, M. W., Harhay, M. O., Zampieri, F. G., Perner, Anders, Møller, Morten Hylander & Jensen, Aksel Karl Georg, 2023, In: BMC Medical Research Methodology. 23, 1, 12 p., 139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2024
  9. Published

    Albumin use in patients with septic shock—Post-hoc analyses of an international randomised fluid trial

    Meyhoff, T. S., Granholm, A., Hjortrup, P. B., Sivapalan, P., Lange, Theis, Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander & Perner, Anders, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 3, p. 372-384 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Changing rates but persisting seasons: patterns of enterovirus infections in hospitalizations and outpatient visits in Denmark 2015-2022

    Johannesen, C. K., Egeskov-cavling, A. M., Jepsen, M. P. G., Lange, Theis, Krause, T. G., Nygaard, Ulrikka & Fischer, Thea Kølsen, 2024, In: Frontiers in Virology. 4, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. E-pub ahead of print

    Effects of sceptical priors on the performance of adaptive clinical trials with binary outcomes

    Granholm, A., Lange, Theis, Harhay, M. O., Perner, Anders, Møller, Morten Hylander & Kaas-Hansen, Benjamin Skov, 2024, (E-pub ahead of print) In: Pharmaceutical Statistics. 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Furosemide versus placebo for fluid overload in intensive care patients-The randomised GODIF trial second version: Statistical analysis plan

    Wichmann, S., Lange, T., Perner, A., Gluud, C., Itenov, T. S., Berthelsen, R. E., Nebrich, L., Wiis, J., Brøchner, A. C., Nielsen, L. G., Behzadi, M. T., Damgaard, K., Andreasen, A. S., Strand, K., Järvisalo, M., Strøm, T., Eschen, C. T., Vang, M. L., Hildebrandt, T., Andersen, F. H. & 14 others, Sigurdsson, M. I., Thomar, K. M., Thygesen, S. K., Troelsen, T. T., Uusalo, P., Jalkanen, V., Illum, D., Sølling, C., Keus, F., Pfortmueller, C. A., Wahlin, R. R., Ostermann, M., Aneman, A. & Bestle, Morten Heiberg, 2024, In: Acta Anaesthesiologica Scandinavica. 68, 1, p. 130-136 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Heterogeneity of treatment effect of higher dose dexamethasone by geographic region (Europe vs. India) in patients with COVID-19 and severe hypoxemia – a post hoc evaluation of the COVID STEROID 2 trial

    Tirupakuzhi Vijayaraghavan, B. K., Granholm, A., Munch, M. W., Kjær, M. B. N., Møller, M. H., Perner, A., Myatra, S. N., Jha, V., Jha, V., Jha, V., Hammond, N., Micallef, S., Venkatesh, B., Hammond, N., Lange, T., Munch, M. W., Myatra, S. N., Tirupakuzhi Vijayaraghavan, B. K., Saseedharan, S., Benfield, T. & 31 others, Wahlin, R. R., Rasmussen, B. S., Andreasen, Anne Sofie, Poulsen, L. M., Cioccari, L., Khan, M. S., Kapadia, F., Divatia, J. V., Brøchner, A. C., Bestle, Morten Heiberg, Helleberg, Marie, Michelsen, J., Padmanaban, A., Bose, N., Møller, A., Borawake, K., Kristiansen, Klaus Tjelle, Shukla, U., Chew, M. S., Ulrik, Charlotte Suppli, Kjær, M. B. N., Møller, Morten Hylander, Meyhoff, T. S., Vesterlund, G. K., Gluud, C., Lange, Theis, Marcussen, Klaus Vennick, Nielsen, H., Jensen, T. S., Perner, Anders & the COVID-STEROID 2 collaborators, T. C. 2. C., 2024, In: The Lancet Regional Health - Southeast Asia. 20, 8 p., 100293.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Long-term cognitive and pulmonary functions following a lower versus a higher oxygenation target in the HOT-ICU and HOT-COVID trials: A protocol update

    Crescioli, E., Riis, J. Ø., Weinreich, U. M., Jensen , Jens-Ulrik Stæhr , Poulsen, L. M., Brøchner, A. C., Lange, Theis, Perner, Anders, Klitgaard, T. L., Schjørring, O. L. & Rasmussen, B. S., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 4, p. 575-578 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium

    Mortensen, C. B., Andersen-Ranberg, N. C., Poulsen, L. M., Granholm, A., Rasmussen, B. S., Kjær, M. B. N., Lange, T., Ebdrup, B. H., Collet, M. O., Andreasen, A. S., Bestle, M. H., Uslu, B., Pedersen, H. S., Nielsen, L. G., Hästbacka, J., Jensen, T. B., Damgaard, K., Sommer, T., Morgen, M., Dey, N. & 6 others, Citerio, G., Estrup, S., Egerod, Ingrid Eugenie, Samuelson, K., Perner, Anders & Mathiesen, Ole, 2024, In: Intensive Care Medicine. 50, p. 103–113 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial

    Nielsen, F. M., Klitgaard, T. L., Siegemund, M., Laake, J. H., Thormar, K. M., Cole, J. M., Aagaard, S. R., Bunzel, A-M. G., Vestergaard, S. R., Langhoff, P. K., Pedersen, C. H., Hejlesen, J. Ø., Abdelhamid, S., Dietz, A., Gebhard, C. E., Zellweger, N., Hollinger, A., Poulsen, L. M., Weihe, S., Andersen-Ranberg, N. C. & 25 others, Pedersen, U. G., Mathiesen, Ole, Andreasen, Anne Sofie, Brix, H., Thomsen, J. J., Petersen, C. H., Bestle, Morten Heiberg, Wichmann, S., Lund, M. S., Mortensen, K. M., Brand, B. A., Haase, N., Iversen, S. A., Marcussen, Klaus Vennick, Brøchner, A. C., Borup, M., Grøfte, T., Hildebrandt, T., Kjær, M. N., Engstrøm, J., Lange, Theis, Perner, Anders, Schjørring, O. L., Rasmussen, B. S. & HOT-COVID Trial Group, H. T. G., 2024, In: JAMA. 331, 14, p. 1185-1194 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Multiplicative and additive interactions between risk factors for coronary heart disease

    Iakunchykova, O., Lange, Theis & Leon, D. A., 2024, In: Annals of Epidemiology. 91, p. 82-84 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Prostacyclin in trauma patients with hemorrhagic shock: A randomized clinical trial

    Jo­hans­son, Pär In­ge­mar , Eriksen, C. F., Bovbjerg, P. E., Gaarder, C., Pall, M., Henriksen, H. H., Pedersen, K. H., Vigstedt, M., Lange, Theis, Næss, P. A., Strømgaard Andersen, M., Kirkegaard, H. & Stensballe, J., 2024, In: Journal of Trauma and Acute Care Surgery. 96, 3, p. 476-481 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Protocol for a randomised controlled trial comparing warfarin with no oral anticoagulation in patients with atrial fibrillation on chronic dialysis: the Danish Warfarin-Dialysis (DANWARD) trial

    Ballegaard, E. L. F., Lindhard, K., Lindhardt, M., Peters, C. D., Thomsen Nielsen, F., Tietze, I. N., Borg, R., Boesby, L., Bertelsen, M. C., Brøsen, J. M. B., Cibulskyte-Ninkovic, D., Rantanen, J. M., Mose, F. H., Kampmann, J. D., Nielsen, A. S., Breinholt, J. K., Kofod, D. H., Bressendorff, I., Clausen, P. V., Lange, T. & 13 others, Køber, Lars Valeur, Kamper, A. L., Bang, C. N. F., Torp-Pedersen, Christian, Hansen, Ditte, Grove, E. L., Gislason, Gunnar Hilmar, Dam Jensen, J., Olesen, J. B., Hornum, Mads, Rix, M., Schou, Morten & Carlson, N., 2024, In: BMJ Open. 14, 2, 7 p., e081961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Restrictive versus standard IV fluid therapy in adult ICU patients with septic shock—Bayesian analyses of the CLASSIC trial

    Sivapalan, P., Meyhoff, T. S., Hjortrup, P. B., Lange, Theis, Kaas-Hansen, Benjamin Skov, Kjær, M. B. N., Laake, J. H., Cronhjort, M., Jakob, S. M., Cecconi, M., Nalos, M., Ostermann, M., Malbrain, M. L. N. G., Møller, Morten Hylander, Perner, Anders & Granholm, A., 2024, In: Acta Anaesthesiologica Scandinavica. 68, 2, p. 236-246 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. E-pub ahead of print

    The Danish-Norwegian randomized trial on beta-blocker therapy after myocardial infarction: Design, rationale, and baseline characteristics

    Kristensen, A. M. D., Munkhaugen, J., Halvorsen, S., Olsen, M. H., Bakken, A., Sehested, T. S. G., Ruddox, V., Lange, Theis, Fagerland, M. W., Torp-Pedersen, Christian, Prescott, Eva & Atar, D., 2024, (E-pub ahead of print) In: European heart journal. Cardiovascular pharmacotherapy.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. E-pub ahead of print

    Underlying pathways of social inequality in tooth loss: the mediating role of sugary beverages and diabetes

    Hach, M., Hvidtfeldt, U. A., Christensen, Lisa Bøge, Lange, Theis, Danielsen, Bo, Osler, Merete, Diderichsen, Finn & Andersen, Ingelise, 2024, (E-pub ahead of print) In: Scandinavian Journal of Public Health. 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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