AMH and other markers of ovarian function in patients with Turner syndrome – a single center experience of transition from pediatric to gynecological follow up
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Standard
AMH and other markers of ovarian function in patients with Turner syndrome – a single center experience of transition from pediatric to gynecological follow up. / Hagen, Casper P.; Fischer, Margit Bistrup; Mola, Gylli; Mikkelsen, Theis Bech; Cleemann, Line Hartvig; Gravholt, Claus Højbjerg; Viuff, Mette H.; Juul, Anders; Pedersen, Anette Tønnes; Main, Katharina Maria.
I: Frontiers in Endocrinology, Bind 14, 1173600, 2023.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - AMH and other markers of ovarian function in patients with Turner syndrome – a single center experience of transition from pediatric to gynecological follow up
AU - Hagen, Casper P.
AU - Fischer, Margit Bistrup
AU - Mola, Gylli
AU - Mikkelsen, Theis Bech
AU - Cleemann, Line Hartvig
AU - Gravholt, Claus Højbjerg
AU - Viuff, Mette H.
AU - Juul, Anders
AU - Pedersen, Anette Tønnes
AU - Main, Katharina Maria
N1 - Publisher Copyright: Copyright © 2023 Hagen, Fischer, Mola, Mikkelsen, Cleemann, Gravholt, Viuff, Juul, Pedersen and Main.
PY - 2023
Y1 - 2023
N2 - Turner syndrome (TS) is a chromosomal disorder that affects about 1 in 2500 female births and is characterized by the partial or complete absence of the second X chromosome. Depending on karyotype, TS is associated with primary ovarian insufficiency (POI). Approximately 50% of girls with a mosaic 45, X/46, XX karyotype may enter puberty spontaneously, but only 5-10% of women with TS achieve pregnancy without egg donation. In this review, we will evaluate the clinical use of markers of ovarian function in TS patients. Based on longitudinal studies of serum concentrations of reproductive hormones as well as ovarian morphology in healthy females and patients with TS, we will evaluate how they can be applied in a clinical setting. This is important when counseling patients and their families about future ovarian function essential for pubertal development and fertility. Furthermore, we will report on 20 years of experience of transition from pediatric to gynecological and adult endocrinological care in our center at Rigshospitalet, Copenhagen, Denmark.
AB - Turner syndrome (TS) is a chromosomal disorder that affects about 1 in 2500 female births and is characterized by the partial or complete absence of the second X chromosome. Depending on karyotype, TS is associated with primary ovarian insufficiency (POI). Approximately 50% of girls with a mosaic 45, X/46, XX karyotype may enter puberty spontaneously, but only 5-10% of women with TS achieve pregnancy without egg donation. In this review, we will evaluate the clinical use of markers of ovarian function in TS patients. Based on longitudinal studies of serum concentrations of reproductive hormones as well as ovarian morphology in healthy females and patients with TS, we will evaluate how they can be applied in a clinical setting. This is important when counseling patients and their families about future ovarian function essential for pubertal development and fertility. Furthermore, we will report on 20 years of experience of transition from pediatric to gynecological and adult endocrinological care in our center at Rigshospitalet, Copenhagen, Denmark.
KW - anti mullerian hormone (AMH)
KW - fertility preservation
KW - FSH (Follicle Stimulating Hormone)
KW - inhibin B
KW - ovarian function
KW - turner syndrome
U2 - 10.3389/fendo.2023.1173600
DO - 10.3389/fendo.2023.1173600
M3 - Review
C2 - 37455919
AN - SCOPUS:85164920774
VL - 14
JO - Frontiers in Endocrinology
JF - Frontiers in Endocrinology
SN - 1664-2392
M1 - 1173600
ER -
ID: 363274259