Vitamin D status and chronic obstructive pulmonary disease: a prospective general population study

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Standard

Vitamin D status and chronic obstructive pulmonary disease : a prospective general population study. / Skaaby, Tea; Husemoen, Lise Lotte Nystrup; Thuesen, Betina Heinsbæk; Pisinger, Charlotta; Jørgensen, Torben; Fenger, Runa Vavia; Linneberg, Allan.

I: PloS one, Bind 9, Nr. 3, e90654, 2014, s. 1-8.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Skaaby, T, Husemoen, LLN, Thuesen, BH, Pisinger, C, Jørgensen, T, Fenger, RV & Linneberg, A 2014, 'Vitamin D status and chronic obstructive pulmonary disease: a prospective general population study', PloS one, bind 9, nr. 3, e90654, s. 1-8. https://doi.org/10.1371/journal.pone.0090654

APA

Skaaby, T., Husemoen, L. L. N., Thuesen, B. H., Pisinger, C., Jørgensen, T., Fenger, R. V., & Linneberg, A. (2014). Vitamin D status and chronic obstructive pulmonary disease: a prospective general population study. PloS one, 9(3), 1-8. [e90654]. https://doi.org/10.1371/journal.pone.0090654

Vancouver

Skaaby T, Husemoen LLN, Thuesen BH, Pisinger C, Jørgensen T, Fenger RV o.a. Vitamin D status and chronic obstructive pulmonary disease: a prospective general population study. PloS one. 2014;9(3):1-8. e90654. https://doi.org/10.1371/journal.pone.0090654

Author

Skaaby, Tea ; Husemoen, Lise Lotte Nystrup ; Thuesen, Betina Heinsbæk ; Pisinger, Charlotta ; Jørgensen, Torben ; Fenger, Runa Vavia ; Linneberg, Allan. / Vitamin D status and chronic obstructive pulmonary disease : a prospective general population study. I: PloS one. 2014 ; Bind 9, Nr. 3. s. 1-8.

Bibtex

@article{d767d77196814c88a1b059f244325d98,
title = "Vitamin D status and chronic obstructive pulmonary disease: a prospective general population study",
abstract = "OBJECTIVES: Vitamin D deficiency is common among persons with chronic obstructive pulmonary disease (COPD). Whether vitamin D affects the development and deterioration of COPD or is a consequence of the disease lacks clarity. We investigated the association between vitamin D status and prevalent and incident COPD in the general population.METHODS: We included a total of 12,041 individuals from three general population studies conducted in 1993-94, 1999-2001, and 2006-2008, respectively, with vitamin D measurements. Information on COPD was obtained from the Danish National Patient Register and The Danish Registry of Causes of Death.RESULTS: There were 85 prevalent and 463 incident cases of COPD (median follow-up 9.7 years). We found a statistically significant inverse association between vitamin D status and prevalent COPD with odds ratio = 0.89 (95% confidence interval, CI: 0.79, 1.0), but no statistically significant association with incident COPD with a hazard ratio = 0.98 (95% CI: 0.94, 1.0), respectively, per 10 nmol/l higher vitamin D status, when adjusted for possible confounders.CONCLUSIONS: We found a statistically significant inverse cross-sectional association between vitamin D status and COPD, but no association between vitamin D status and incident COPD.",
keywords = "Adolescent, Adult, Aged, Cross-Sectional Studies, Denmark, Female, Humans, Incidence, Male, Middle Aged, Prevalence, Proportional Hazards Models, Prospective Studies, Pulmonary Disease, Chronic Obstructive, Risk Factors, Vitamin D, Vitamin D Deficiency, Young Adult",
author = "Tea Skaaby and Husemoen, {Lise Lotte Nystrup} and Thuesen, {Betina Heinsb{\ae}k} and Charlotta Pisinger and Torben J{\o}rgensen and Fenger, {Runa Vavia} and Allan Linneberg",
year = "2014",
doi = "10.1371/journal.pone.0090654",
language = "English",
volume = "9",
pages = "1--8",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "3",

}

RIS

TY - JOUR

T1 - Vitamin D status and chronic obstructive pulmonary disease

T2 - a prospective general population study

AU - Skaaby, Tea

AU - Husemoen, Lise Lotte Nystrup

AU - Thuesen, Betina Heinsbæk

AU - Pisinger, Charlotta

AU - Jørgensen, Torben

AU - Fenger, Runa Vavia

AU - Linneberg, Allan

PY - 2014

Y1 - 2014

N2 - OBJECTIVES: Vitamin D deficiency is common among persons with chronic obstructive pulmonary disease (COPD). Whether vitamin D affects the development and deterioration of COPD or is a consequence of the disease lacks clarity. We investigated the association between vitamin D status and prevalent and incident COPD in the general population.METHODS: We included a total of 12,041 individuals from three general population studies conducted in 1993-94, 1999-2001, and 2006-2008, respectively, with vitamin D measurements. Information on COPD was obtained from the Danish National Patient Register and The Danish Registry of Causes of Death.RESULTS: There were 85 prevalent and 463 incident cases of COPD (median follow-up 9.7 years). We found a statistically significant inverse association between vitamin D status and prevalent COPD with odds ratio = 0.89 (95% confidence interval, CI: 0.79, 1.0), but no statistically significant association with incident COPD with a hazard ratio = 0.98 (95% CI: 0.94, 1.0), respectively, per 10 nmol/l higher vitamin D status, when adjusted for possible confounders.CONCLUSIONS: We found a statistically significant inverse cross-sectional association between vitamin D status and COPD, but no association between vitamin D status and incident COPD.

AB - OBJECTIVES: Vitamin D deficiency is common among persons with chronic obstructive pulmonary disease (COPD). Whether vitamin D affects the development and deterioration of COPD or is a consequence of the disease lacks clarity. We investigated the association between vitamin D status and prevalent and incident COPD in the general population.METHODS: We included a total of 12,041 individuals from three general population studies conducted in 1993-94, 1999-2001, and 2006-2008, respectively, with vitamin D measurements. Information on COPD was obtained from the Danish National Patient Register and The Danish Registry of Causes of Death.RESULTS: There were 85 prevalent and 463 incident cases of COPD (median follow-up 9.7 years). We found a statistically significant inverse association between vitamin D status and prevalent COPD with odds ratio = 0.89 (95% confidence interval, CI: 0.79, 1.0), but no statistically significant association with incident COPD with a hazard ratio = 0.98 (95% CI: 0.94, 1.0), respectively, per 10 nmol/l higher vitamin D status, when adjusted for possible confounders.CONCLUSIONS: We found a statistically significant inverse cross-sectional association between vitamin D status and COPD, but no association between vitamin D status and incident COPD.

KW - Adolescent

KW - Adult

KW - Aged

KW - Cross-Sectional Studies

KW - Denmark

KW - Female

KW - Humans

KW - Incidence

KW - Male

KW - Middle Aged

KW - Prevalence

KW - Proportional Hazards Models

KW - Prospective Studies

KW - Pulmonary Disease, Chronic Obstructive

KW - Risk Factors

KW - Vitamin D

KW - Vitamin D Deficiency

KW - Young Adult

U2 - 10.1371/journal.pone.0090654

DO - 10.1371/journal.pone.0090654

M3 - Journal article

C2 - 24594696

VL - 9

SP - 1

EP - 8

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 3

M1 - e90654

ER -

ID: 137511897