Self-rated health in patients with mild Alzheimer's disease: baseline data from the Danish Alzheimer Intervention Study
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Self-rated health in patients with mild Alzheimer's disease: baseline data from the Danish Alzheimer Intervention Study. / Waldorff, Frans Boch; Nielsen, Anni B S; Waldemar, Gunhild.
I: Archives of Gerontology and Geriatrics, Bind 50, Nr. 1, 2010, s. 1-5.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › fagfællebedømt
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TY - JOUR
T1 - Self-rated health in patients with mild Alzheimer's disease: baseline data from the Danish Alzheimer Intervention Study
AU - Waldorff, Frans Boch
AU - Nielsen, Anni B S
AU - Waldemar, Gunhild
PY - 2010
Y1 - 2010
N2 - In both epidemiological studies and in clinical trials the patients' own health perception, self-rated health (SRH), measured by a single question, is frequently used as an overall health assessment. Researchers have been encouraged to examine ways of assessing SRH in cognitively impaired persons, but the validity and the influence on other factors on SRH among cognitively impaired persons remain unknown. This study reports how patients with mild Alzheimer's disease (AD) report SRH and which factors influence SRH. The study was based on baseline data from 321 home living patients with mild AD who participated in the Danish Alzheimer Intervention Study (DAISY). Analysis using the generalized estimating equation (GEE) models revealed that good/excellent SRH among patients with mild AD were associated with longer education, lack of other chronic conditions, higher scores of quality of life (QOL), lower scores of mini mental state examination (MMSE), and loss of insight in own cognitive deficits. The present results indicate that SRH reported by patients with mild AD may differ from SRH among cognitively intact persons. Further research is needed in order to establish the validity and implication of SRH in this group of patients.
AB - In both epidemiological studies and in clinical trials the patients' own health perception, self-rated health (SRH), measured by a single question, is frequently used as an overall health assessment. Researchers have been encouraged to examine ways of assessing SRH in cognitively impaired persons, but the validity and the influence on other factors on SRH among cognitively impaired persons remain unknown. This study reports how patients with mild Alzheimer's disease (AD) report SRH and which factors influence SRH. The study was based on baseline data from 321 home living patients with mild AD who participated in the Danish Alzheimer Intervention Study (DAISY). Analysis using the generalized estimating equation (GEE) models revealed that good/excellent SRH among patients with mild AD were associated with longer education, lack of other chronic conditions, higher scores of quality of life (QOL), lower scores of mini mental state examination (MMSE), and loss of insight in own cognitive deficits. The present results indicate that SRH reported by patients with mild AD may differ from SRH among cognitively intact persons. Further research is needed in order to establish the validity and implication of SRH in this group of patients.
KW - Activities of Daily Living
KW - Age Factors
KW - Aged
KW - Aged, 80 and over
KW - Alzheimer Disease
KW - Caregivers
KW - Cognition Disorders
KW - Confidence Intervals
KW - Denmark
KW - Disability Evaluation
KW - Female
KW - Health Status
KW - Humans
KW - Male
KW - Middle Aged
KW - Multivariate Analysis
KW - Odds Ratio
KW - Perceptual Disorders
KW - Probability
KW - Quality of Life
KW - Self Concept
KW - Severity of Illness Index
KW - Sex Factors
KW - Single-Blind Method
U2 - 10.1016/j.archger.2008.12.010
DO - 10.1016/j.archger.2008.12.010
M3 - Journal article
C2 - 19181399
VL - 50
SP - 1
EP - 5
JO - Archives of Gerontology and Geriatrics
JF - Archives of Gerontology and Geriatrics
SN - 0167-4943
IS - 1
ER -
ID: 33243476