Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing. / Løkkegaard, Thomas; Pedersen, Tina Heidi; Lind, Bent; Siersma, Volkert Dirk; Waldorff, Frans Borch.

I: Danish Medical Journal, Bind 62, Nr. 2, A5010, 02.2015, s. 1-6.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Løkkegaard, T, Pedersen, TH, Lind, B, Siersma, VD & Waldorff, FB 2015, 'Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing.', Danish Medical Journal, bind 62, nr. 2, A5010, s. 1-6. <http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2015/DMJ_2015_02/A5010>

APA

Løkkegaard, T., Pedersen, T. H., Lind, B., Siersma, V. D., & Waldorff, F. B. (2015). Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing. Danish Medical Journal, 62(2), 1-6. [A5010]. http://www.danmedj.dk/portal/page/portal/danmedj.dk/dmj_forside/PAST_ISSUE/2015/DMJ_2015_02/A5010

Vancouver

Løkkegaard T, Pedersen TH, Lind B, Siersma VD, Waldorff FB. Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing. Danish Medical Journal. 2015 feb.;62(2):1-6. A5010.

Author

Løkkegaard, Thomas ; Pedersen, Tina Heidi ; Lind, Bent ; Siersma, Volkert Dirk ; Waldorff, Frans Borch. / Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing. I: Danish Medical Journal. 2015 ; Bind 62, Nr. 2. s. 1-6.

Bibtex

@article{ae6f4cb7d31d47adac8c01c7b724f5c8,
title = "Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing.",
abstract = "INTRODUCTION: Oral anticoagulation treatment (OACT)with warfarin is common in general practice. Increasingly,international normalised ratio (INR) point of care testing(POCT) is being used to manage patients. The aim of thisstudy was to describe and analyse the quality of OACT withwarfarin in general practice in the Capital Region of Denmarkusing INR POCT.METHODS: A total of 20 general practices, ten singlehandedand ten group practices using INR POCT, were randomlyselected to participate in the study. Practice organisationand patient characteristics were recorded. INRmeasurements were collected retrospectively for a periodof six months. For each patient, time in therapeutic range(TTR) was calculated and correlated with practice and patientcharacteristics using multilevel linear regressionmodels.RESULTS: We identified 447 patients in warfarin treatmentin the 20 practices using POCT (median: 19 patients; range:6-55). The mean TTR for all patients was 69.3% (standarddeviation (SD) = 24%), and for all practices the mean TTRwas 67.3% (SD = 6.7%). The TTR in single-handed practiceswas lower than in group practices, 64.6% (SD = 8.0%) and70.0% (SD = 3.6%), respectively; but the difference was notsignificant (4.2 percentage points (pp); 95% confidenceinterval (CI): –0.8-9.2). Short sampling intervals, e.g. 10-20days (–11 pp, 95% CI: –16-–6)) and lack of diagnostic coding(–11.8 pp; 95% CI: –19.9-–3.7) were correlated with a lowTTR.CONCLUSION: In our study most of the general practices usingINR POCT in the management of patients in warfarintreatment provided good quality of care. Sampling intervaland diagnostic coding were significantly correlated withtreatment quality.FUNDING: The study received financial support from theSarah Krabbe Foundation, the General Practitioners{\textquoteright} Educationand Development Foundation, and Quality in PrimaryCare (KAP-H) – the Capital Region of Denmark.TRIAL REGISTRATION: not relevant.",
keywords = "care, GENERAL-PRACTICE, general practice, Practice, semrap-2015-1",
author = "Thomas L{\o}kkegaard and Pedersen, {Tina Heidi} and Bent Lind and Siersma, {Volkert Dirk} and Waldorff, {Frans Borch}",
year = "2015",
month = feb,
language = "English",
volume = "62",
pages = "1--6",
journal = "Danish Medical Journal",
issn = "2245-1919",
publisher = "Almindelige Danske Laegeforening",
number = "2",

}

RIS

TY - JOUR

T1 - Good quality of oral anticoagulation treatment in general practice using international normalised ratio point of care testing.

AU - Løkkegaard, Thomas

AU - Pedersen, Tina Heidi

AU - Lind, Bent

AU - Siersma, Volkert Dirk

AU - Waldorff, Frans Borch

PY - 2015/2

Y1 - 2015/2

N2 - INTRODUCTION: Oral anticoagulation treatment (OACT)with warfarin is common in general practice. Increasingly,international normalised ratio (INR) point of care testing(POCT) is being used to manage patients. The aim of thisstudy was to describe and analyse the quality of OACT withwarfarin in general practice in the Capital Region of Denmarkusing INR POCT.METHODS: A total of 20 general practices, ten singlehandedand ten group practices using INR POCT, were randomlyselected to participate in the study. Practice organisationand patient characteristics were recorded. INRmeasurements were collected retrospectively for a periodof six months. For each patient, time in therapeutic range(TTR) was calculated and correlated with practice and patientcharacteristics using multilevel linear regressionmodels.RESULTS: We identified 447 patients in warfarin treatmentin the 20 practices using POCT (median: 19 patients; range:6-55). The mean TTR for all patients was 69.3% (standarddeviation (SD) = 24%), and for all practices the mean TTRwas 67.3% (SD = 6.7%). The TTR in single-handed practiceswas lower than in group practices, 64.6% (SD = 8.0%) and70.0% (SD = 3.6%), respectively; but the difference was notsignificant (4.2 percentage points (pp); 95% confidenceinterval (CI): –0.8-9.2). Short sampling intervals, e.g. 10-20days (–11 pp, 95% CI: –16-–6)) and lack of diagnostic coding(–11.8 pp; 95% CI: –19.9-–3.7) were correlated with a lowTTR.CONCLUSION: In our study most of the general practices usingINR POCT in the management of patients in warfarintreatment provided good quality of care. Sampling intervaland diagnostic coding were significantly correlated withtreatment quality.FUNDING: The study received financial support from theSarah Krabbe Foundation, the General Practitioners’ Educationand Development Foundation, and Quality in PrimaryCare (KAP-H) – the Capital Region of Denmark.TRIAL REGISTRATION: not relevant.

AB - INTRODUCTION: Oral anticoagulation treatment (OACT)with warfarin is common in general practice. Increasingly,international normalised ratio (INR) point of care testing(POCT) is being used to manage patients. The aim of thisstudy was to describe and analyse the quality of OACT withwarfarin in general practice in the Capital Region of Denmarkusing INR POCT.METHODS: A total of 20 general practices, ten singlehandedand ten group practices using INR POCT, were randomlyselected to participate in the study. Practice organisationand patient characteristics were recorded. INRmeasurements were collected retrospectively for a periodof six months. For each patient, time in therapeutic range(TTR) was calculated and correlated with practice and patientcharacteristics using multilevel linear regressionmodels.RESULTS: We identified 447 patients in warfarin treatmentin the 20 practices using POCT (median: 19 patients; range:6-55). The mean TTR for all patients was 69.3% (standarddeviation (SD) = 24%), and for all practices the mean TTRwas 67.3% (SD = 6.7%). The TTR in single-handed practiceswas lower than in group practices, 64.6% (SD = 8.0%) and70.0% (SD = 3.6%), respectively; but the difference was notsignificant (4.2 percentage points (pp); 95% confidenceinterval (CI): –0.8-9.2). Short sampling intervals, e.g. 10-20days (–11 pp, 95% CI: –16-–6)) and lack of diagnostic coding(–11.8 pp; 95% CI: –19.9-–3.7) were correlated with a lowTTR.CONCLUSION: In our study most of the general practices usingINR POCT in the management of patients in warfarintreatment provided good quality of care. Sampling intervaland diagnostic coding were significantly correlated withtreatment quality.FUNDING: The study received financial support from theSarah Krabbe Foundation, the General Practitioners’ Educationand Development Foundation, and Quality in PrimaryCare (KAP-H) – the Capital Region of Denmark.TRIAL REGISTRATION: not relevant.

KW - care

KW - GENERAL-PRACTICE

KW - general practice

KW - Practice

KW - semrap-2015-1

UR - http://www.ncbi.nlm.nih.gov/pubmed/25634508

M3 - Journal article

VL - 62

SP - 1

EP - 6

JO - Danish Medical Journal

JF - Danish Medical Journal

SN - 2245-1919

IS - 2

M1 - A5010

ER -

ID: 141093445