Quantifying mediating effects of endogenous estrogen and insulin in the relation between obesity, alcohol consumption, and breast cancer

Research output: Contribution to journalJournal articleResearchpeer-review

  • Ulla A Hvidtfeldt
  • Marc J Gunter
  • Lange, Theis
  • Rowan T Chlebowski
  • Dorothy Lane
  • Ghada N Farhat
  • Matthew S Freiberg
  • Niels Keiding
  • Jennifer S Lee
  • Ross Prentice
  • Anne Tjønneland
  • Mara Z Vitolins
  • Silvia Wassertheil-Smoller
  • Howard D Strickler
  • Rod, Naja Hulvej
Increased exposure to endogenous estrogen and/or insulin may partly explain the relationship of obesity, physical inactivity, and alcohol consumption and postmenopausal breast cancer. However, these potential mediating effects have not been formally quantified in a survival analysis setting.
Original languageEnglish
JournalCancer Epidemiology, Biomarkers & Prevention
Issue number7
Pages (from-to)1203-12
Number of pages10
Publication statusPublished - 2012

    Research areas

  • Aged, Alcohol Drinking, Body Mass Index, Breast Neoplasms, Case-Control Studies, Estrogens, Female, Follow-Up Studies, Humans, Hypoglycemic Agents, Incidence, Insulin, Male, Middle Aged, Obesity, Prognosis, United States, Women's Health

ID: 44309046