Measuring bothersome menopausal symptoms: development and validation of the MenoScores questionnaire

Research output: Contribution to journalJournal articlepeer-review

Standard

Measuring bothersome menopausal symptoms : development and validation of the MenoScores questionnaire. / Lund, Kamma Sundgaard; Siersma, Volkert Dirk; Christensen, Karl Bang; Waldorff, Frans Boch; Brodersen, John.

In: Health and Quality of Life Outcomes, Vol. 16, 97, 2018.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Lund, KS, Siersma, VD, Christensen, KB, Waldorff, FB & Brodersen, J 2018, 'Measuring bothersome menopausal symptoms: development and validation of the MenoScores questionnaire', Health and Quality of Life Outcomes, vol. 16, 97. https://doi.org/10.1186/s12955-018-0927-6

APA

Lund, K. S., Siersma, V. D., Christensen, K. B., Waldorff, F. B., & Brodersen, J. (2018). Measuring bothersome menopausal symptoms: development and validation of the MenoScores questionnaire. Health and Quality of Life Outcomes, 16, [97]. https://doi.org/10.1186/s12955-018-0927-6

Vancouver

Lund KS, Siersma VD, Christensen KB, Waldorff FB, Brodersen J. Measuring bothersome menopausal symptoms: development and validation of the MenoScores questionnaire. Health and Quality of Life Outcomes. 2018;16. 97. https://doi.org/10.1186/s12955-018-0927-6

Author

Lund, Kamma Sundgaard ; Siersma, Volkert Dirk ; Christensen, Karl Bang ; Waldorff, Frans Boch ; Brodersen, John. / Measuring bothersome menopausal symptoms : development and validation of the MenoScores questionnaire. In: Health and Quality of Life Outcomes. 2018 ; Vol. 16.

Bibtex

@article{0d0107f4817e48d3b4f9f96d425c629d,
title = "Measuring bothersome menopausal symptoms: development and validation of the MenoScores questionnaire",
abstract = "BACKGROUND: The experience of menopausal symptoms is common and an adequate patient-reported outcome measure is crucial in studies where women are treated for these symptoms. The aims of this study were to identify a patient-reported outcome measure for bothersome menopausal symptoms and, in the absence of an adequate tool, to develop a new measure with high content validity, and to validate it using modern psychometric methods. METHODS: The literature was reviewed for existing questionnaires and checklists for bothersome menopausal symptoms. Relevant items were extracted and subsequently tested in group interviews, single interviews, and pilot tests. A patient-reported outcome measure was drafted and completed by 1504 women. Data was collected and psychometrically validated using item-response theory Rasch Models. RESULTS: All questionnaires identified in the literature lacked content validity regarding bothersome menopausal symptoms and none were validated using item-response theory. Our content validation resulted in a draft measurement encompassing 122 items across eight domains. Following psychometrical validation, the final version of our patient-reported outcome measure, named the MenoScores Questionnaire, encompassed 51 items, including one single item, covering 11 scales. CONCLUSION: Menopausal symptoms are multidimensional with some symptoms unquestionably related to the menopausal transition. We identified four constructs of importance: hot flushes, day-and-night sweats, general sweating, and menopausal-specific sleeping problems. The MenoScores Questionnaire is condition-specific with high content validity and adequate psychometrical properties. It is designed to measure bothersome menopausal symptoms and all scales are developed and psychometrically validated using item-response theory Rasch Models. TRIAL REGISTRATION: Approved by the Danish Data Agency (J.nr. 2015-41-4057). Ethics Committee approval was not required.",
author = "Lund, {Kamma Sundgaard} and Siersma, {Volkert Dirk} and Christensen, {Karl Bang} and Waldorff, {Frans Boch} and John Brodersen",
year = "2018",
doi = "10.1186/s12955-018-0927-6",
language = "English",
volume = "16",
journal = "Health and Quality of Life Outcomes",
issn = "1477-7525",
publisher = "BioMed Central",

}

RIS

TY - JOUR

T1 - Measuring bothersome menopausal symptoms

T2 - development and validation of the MenoScores questionnaire

AU - Lund, Kamma Sundgaard

AU - Siersma, Volkert Dirk

AU - Christensen, Karl Bang

AU - Waldorff, Frans Boch

AU - Brodersen, John

PY - 2018

Y1 - 2018

N2 - BACKGROUND: The experience of menopausal symptoms is common and an adequate patient-reported outcome measure is crucial in studies where women are treated for these symptoms. The aims of this study were to identify a patient-reported outcome measure for bothersome menopausal symptoms and, in the absence of an adequate tool, to develop a new measure with high content validity, and to validate it using modern psychometric methods. METHODS: The literature was reviewed for existing questionnaires and checklists for bothersome menopausal symptoms. Relevant items were extracted and subsequently tested in group interviews, single interviews, and pilot tests. A patient-reported outcome measure was drafted and completed by 1504 women. Data was collected and psychometrically validated using item-response theory Rasch Models. RESULTS: All questionnaires identified in the literature lacked content validity regarding bothersome menopausal symptoms and none were validated using item-response theory. Our content validation resulted in a draft measurement encompassing 122 items across eight domains. Following psychometrical validation, the final version of our patient-reported outcome measure, named the MenoScores Questionnaire, encompassed 51 items, including one single item, covering 11 scales. CONCLUSION: Menopausal symptoms are multidimensional with some symptoms unquestionably related to the menopausal transition. We identified four constructs of importance: hot flushes, day-and-night sweats, general sweating, and menopausal-specific sleeping problems. The MenoScores Questionnaire is condition-specific with high content validity and adequate psychometrical properties. It is designed to measure bothersome menopausal symptoms and all scales are developed and psychometrically validated using item-response theory Rasch Models. TRIAL REGISTRATION: Approved by the Danish Data Agency (J.nr. 2015-41-4057). Ethics Committee approval was not required.

AB - BACKGROUND: The experience of menopausal symptoms is common and an adequate patient-reported outcome measure is crucial in studies where women are treated for these symptoms. The aims of this study were to identify a patient-reported outcome measure for bothersome menopausal symptoms and, in the absence of an adequate tool, to develop a new measure with high content validity, and to validate it using modern psychometric methods. METHODS: The literature was reviewed for existing questionnaires and checklists for bothersome menopausal symptoms. Relevant items were extracted and subsequently tested in group interviews, single interviews, and pilot tests. A patient-reported outcome measure was drafted and completed by 1504 women. Data was collected and psychometrically validated using item-response theory Rasch Models. RESULTS: All questionnaires identified in the literature lacked content validity regarding bothersome menopausal symptoms and none were validated using item-response theory. Our content validation resulted in a draft measurement encompassing 122 items across eight domains. Following psychometrical validation, the final version of our patient-reported outcome measure, named the MenoScores Questionnaire, encompassed 51 items, including one single item, covering 11 scales. CONCLUSION: Menopausal symptoms are multidimensional with some symptoms unquestionably related to the menopausal transition. We identified four constructs of importance: hot flushes, day-and-night sweats, general sweating, and menopausal-specific sleeping problems. The MenoScores Questionnaire is condition-specific with high content validity and adequate psychometrical properties. It is designed to measure bothersome menopausal symptoms and all scales are developed and psychometrically validated using item-response theory Rasch Models. TRIAL REGISTRATION: Approved by the Danish Data Agency (J.nr. 2015-41-4057). Ethics Committee approval was not required.

U2 - 10.1186/s12955-018-0927-6

DO - 10.1186/s12955-018-0927-6

M3 - Journal article

C2 - 29769073

VL - 16

JO - Health and Quality of Life Outcomes

JF - Health and Quality of Life Outcomes

SN - 1477-7525

M1 - 97

ER -

ID: 196878795