Estimating a Preference-Based Index for Mental Health From the Recovering Quality of Life Measure: Valuation of Recovering Quality of Life Utility Index

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  • Anju Devianee Keetharuth
  • Donna Rowen
  • Jakob Bue Bjorner
  • John Brazier

BACKGROUND: There are increasing concerns about the appropriateness of generic preference-based measures to capture health benefits in the area of mental health.

OBJECTIVES: The aim of this study is to estimate preference weights for a new measure, Recovering Quality of Life (ReQoL-10), to better capture the benefits of mental healthcare.

METHODS: Psychometric analyses of a larger sample of mental health service users (n = 4266) using confirmatory factor analyses and item response theory were used to derive a health state classification system and inform the selection of health states for utility assessment. A valuation survey with members of the UK public representative in terms of age, sex, and region was conducted using face-to-face interviewer administered time-trade-off with props. A series of regression models were fitted to the data and the best performing model selected for the scoring algorithm.

RESULTS: The ReQoL-Utility Index (UI) classification system comprises 6 mental health items and 1 physical health item. Sixty-four health states were valued by 305 participants. The preferred model was a random effects model, with significant and consistent coefficients and best model fit. Estimated utilities modeled for all health states ranged from -0.195 (state worse than dead) to 1 (best possible state).

CONCLUSIONS: The development of the ReQoL-UI is based on a novel application of item response theory methods for generating the classification system and selecting health states for valuation. Conventional time-trade-off was used to elicit utility values that are modeled to enable the generation of QALYs for use in cost-utility analysis of mental health interventions.

Original languageEnglish
JournalValue in Health
Issue number2
Pages (from-to)281-290
Number of pages10
Publication statusPublished - 2021

Bibliographical note

Copyright © 2020 ISPOR–The Professional Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.

    Research areas

  • Adolescent, Adult, Aged, Aged, 80 and over, Cost-Benefit Analysis/methods, Female, Health Status, Hope, Humans, Interpersonal Relations, Leisure Activities, Male, Mental Health/economics, Middle Aged, Personal Autonomy, Psychometrics, Quality of Life/psychology, Socioeconomic Factors, Surveys and Questionnaires/standards, Young Adult

ID: 286929441