Treating pigs: Balancing standardisation and individual treatments in translational neonatology research
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Treating pigs : Balancing standardisation and individual treatments in translational neonatology research. / Dam, Mie S.; Svendsen, Mette N.
I: BioSocieties, Bind 13, Nr. 2, 2018, s. 349–367.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Treating pigs
T2 - Balancing standardisation and individual treatments in translational neonatology research
AU - Dam, Mie S.
AU - Svendsen, Mette N.
PY - 2018
Y1 - 2018
N2 - This paper explores how animal modelling is negotiated and practised in the field of translational neonatology research in Denmark. Based on ethnography from a biomedical research centre, NEOMUNE, in which veterinary and medical scientists worked on developing a ‘preterm pig brain model’, we examine how they strived to balance traditional scientific norms of standardisation against clinical researchers’ requests for clinical care in the modelling practice. We develop the notion of ‘patientising’ to capture how the research piglets are made to model not only the biological consequences of prematurity, but also the suffering of the human patient entitled to individual care. Based on this ethnographic fieldwork we argue that the demand for clinical relevance in translational research highlights the animal laboratory as also being a “moral laboratory” (Mattingly, 2014). In seeking to align research piglets and human infants, the researchers engage closely interdependent scientific and moral uncertainties as they work out the proper relations between the suffering of the research animal and the health of the human infant.
AB - This paper explores how animal modelling is negotiated and practised in the field of translational neonatology research in Denmark. Based on ethnography from a biomedical research centre, NEOMUNE, in which veterinary and medical scientists worked on developing a ‘preterm pig brain model’, we examine how they strived to balance traditional scientific norms of standardisation against clinical researchers’ requests for clinical care in the modelling practice. We develop the notion of ‘patientising’ to capture how the research piglets are made to model not only the biological consequences of prematurity, but also the suffering of the human patient entitled to individual care. Based on this ethnographic fieldwork we argue that the demand for clinical relevance in translational research highlights the animal laboratory as also being a “moral laboratory” (Mattingly, 2014). In seeking to align research piglets and human infants, the researchers engage closely interdependent scientific and moral uncertainties as they work out the proper relations between the suffering of the research animal and the health of the human infant.
KW - animal models
KW - moral reasoning
KW - multispecies-ethnography
KW - neonatology
KW - suffering
KW - translational research
U2 - 10.1057/s41292-017-0071-2
DO - 10.1057/s41292-017-0071-2
M3 - Journal article
AN - SCOPUS:85014481349
VL - 13
SP - 349
EP - 367
JO - BioSocieties
JF - BioSocieties
SN - 1745-8552
IS - 2
ER -
ID: 187011511