The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children

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The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children. / Lee, Young Ah; Kim, Jin Hee; Jung, Hae Woon; Lim, Youn-Hee; Bae, Sanghyuk; Kho, Younglim; Hong, Yun-Chul; Shin, Choong Ho; Yang, Sei Won.

I: The Science of the Total Environment, Bind 628-629, 2018, s. 226-232.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lee, YA, Kim, JH, Jung, HW, Lim, Y-H, Bae, S, Kho, Y, Hong, Y-C, Shin, CH & Yang, SW 2018, 'The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children', The Science of the Total Environment, bind 628-629, s. 226-232. https://doi.org/10.1016/j.scitotenv.2018.02.050

APA

Lee, Y. A., Kim, J. H., Jung, H. W., Lim, Y-H., Bae, S., Kho, Y., Hong, Y-C., Shin, C. H., & Yang, S. W. (2018). The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children. The Science of the Total Environment, 628-629, 226-232. https://doi.org/10.1016/j.scitotenv.2018.02.050

Vancouver

Lee YA, Kim JH, Jung HW, Lim Y-H, Bae S, Kho Y o.a. The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children. The Science of the Total Environment. 2018;628-629:226-232. https://doi.org/10.1016/j.scitotenv.2018.02.050

Author

Lee, Young Ah ; Kim, Jin Hee ; Jung, Hae Woon ; Lim, Youn-Hee ; Bae, Sanghyuk ; Kho, Younglim ; Hong, Yun-Chul ; Shin, Choong Ho ; Yang, Sei Won. / The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children. I: The Science of the Total Environment. 2018 ; Bind 628-629. s. 226-232.

Bibtex

@article{5349b00774cf4d0f9324b26f1678de0c,

title = "The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children",

abstract = "The relationship between the serum concentrations of perfluoroalkyl compounds (PFCs) and growth parameters was investigated in 2-year-old Korean children. The study included 361 children aged 2years (192 boys and 169 girls; 22-27months), born at term appropriate-for-gestational-age, who visited between 2012 and 2013. Growth parameters of height and weight, and serum samples were collected from 2-year-old children. Four PFCs (perfluorohexane sulfonic acid [PFHxS], perfluorooctane sulfonic acid [PFOS], perfluorooctanoic acid [PFOA], and perfluorononanoic acid [PFNA]), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), and perfluoroheptanoic acid (PFHpA) were detected in >99, 93.4, 89.8, and 74.2% of the serum samples, respectively. The duration of breastfeeding was positively associated with the serum concentrations of ln-transformed PFHxS, PFOS, PFHpA, PFOA, PFNA, PFDA, and PFUnDA (all P<0.001). Height at 2years of age was inversely related to PFHxS, PFOS, PFOA, PFNA, and PFDA concentrations (adjusted β per ln unit [95% confidence interval, CI]: -0.84 [-1.26, -0.42], -0.77 [-1.27, -0.15], -0.91 [-1.36, -0.47], -0.48 [-1.40, -0.51], and -0.44 [-0.77, -0.10] cm, respectively), after adjusting for age, sex, and midparental height. Weight at 2years of age was inversely associated with PFNA (adjusted β per ln unit [95% CI]: -0.32 [-0.48, -0.15] kg), after adjusting for age, sex, and parental BMI. In conclusion, the serum concentrations of PFCs were inversely associated with growth parameters in 2-year-old children.",

keywords = "Alkanesulfonic Acids, Caprylates, Child, Preschool, Environmental Exposure/statistics & numerical data, Environmental Pollutants/blood, Female, Fluorocarbons/blood, Growth and Development/drug effects, Humans, Male, Sulfonic Acids, Time",

author = "Lee, {Young Ah} and Kim, {Jin Hee} and Jung, {Hae Woon} and Youn-Hee Lim and Sanghyuk Bae and Younglim Kho and Yun-Chul Hong and Shin, {Choong Ho} and Yang, {Sei Won}",

year = "2018",

doi = "10.1016/j.scitotenv.2018.02.050",

language = "English",

volume = "628-629",

pages = "226--232",

journal = "Science of the Total Environment",

issn = "0048-9697",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - The serum concentrations of perfluoroalkyl compounds were inversely associated with growth parameters in 2-year old children

AU - Lee, Young Ah

AU - Kim, Jin Hee

AU - Jung, Hae Woon

AU - Lim, Youn-Hee

AU - Bae, Sanghyuk

AU - Kho, Younglim

AU - Hong, Yun-Chul

AU - Shin, Choong Ho

AU - Yang, Sei Won

PY - 2018

Y1 - 2018

N2 - The relationship between the serum concentrations of perfluoroalkyl compounds (PFCs) and growth parameters was investigated in 2-year-old Korean children. The study included 361 children aged 2years (192 boys and 169 girls; 22-27months), born at term appropriate-for-gestational-age, who visited between 2012 and 2013. Growth parameters of height and weight, and serum samples were collected from 2-year-old children. Four PFCs (perfluorohexane sulfonic acid [PFHxS], perfluorooctane sulfonic acid [PFOS], perfluorooctanoic acid [PFOA], and perfluorononanoic acid [PFNA]), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), and perfluoroheptanoic acid (PFHpA) were detected in >99, 93.4, 89.8, and 74.2% of the serum samples, respectively. The duration of breastfeeding was positively associated with the serum concentrations of ln-transformed PFHxS, PFOS, PFHpA, PFOA, PFNA, PFDA, and PFUnDA (all P<0.001). Height at 2years of age was inversely related to PFHxS, PFOS, PFOA, PFNA, and PFDA concentrations (adjusted β per ln unit [95% confidence interval, CI]: -0.84 [-1.26, -0.42], -0.77 [-1.27, -0.15], -0.91 [-1.36, -0.47], -0.48 [-1.40, -0.51], and -0.44 [-0.77, -0.10] cm, respectively), after adjusting for age, sex, and midparental height. Weight at 2years of age was inversely associated with PFNA (adjusted β per ln unit [95% CI]: -0.32 [-0.48, -0.15] kg), after adjusting for age, sex, and parental BMI. In conclusion, the serum concentrations of PFCs were inversely associated with growth parameters in 2-year-old children.

AB - The relationship between the serum concentrations of perfluoroalkyl compounds (PFCs) and growth parameters was investigated in 2-year-old Korean children. The study included 361 children aged 2years (192 boys and 169 girls; 22-27months), born at term appropriate-for-gestational-age, who visited between 2012 and 2013. Growth parameters of height and weight, and serum samples were collected from 2-year-old children. Four PFCs (perfluorohexane sulfonic acid [PFHxS], perfluorooctane sulfonic acid [PFOS], perfluorooctanoic acid [PFOA], and perfluorononanoic acid [PFNA]), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), and perfluoroheptanoic acid (PFHpA) were detected in >99, 93.4, 89.8, and 74.2% of the serum samples, respectively. The duration of breastfeeding was positively associated with the serum concentrations of ln-transformed PFHxS, PFOS, PFHpA, PFOA, PFNA, PFDA, and PFUnDA (all P<0.001). Height at 2years of age was inversely related to PFHxS, PFOS, PFOA, PFNA, and PFDA concentrations (adjusted β per ln unit [95% confidence interval, CI]: -0.84 [-1.26, -0.42], -0.77 [-1.27, -0.15], -0.91 [-1.36, -0.47], -0.48 [-1.40, -0.51], and -0.44 [-0.77, -0.10] cm, respectively), after adjusting for age, sex, and midparental height. Weight at 2years of age was inversely associated with PFNA (adjusted β per ln unit [95% CI]: -0.32 [-0.48, -0.15] kg), after adjusting for age, sex, and parental BMI. In conclusion, the serum concentrations of PFCs were inversely associated with growth parameters in 2-year-old children.

KW - Alkanesulfonic Acids

KW - Caprylates

KW - Child, Preschool

KW - Environmental Exposure/statistics & numerical data

KW - Environmental Pollutants/blood

KW - Female

KW - Fluorocarbons/blood

KW - Growth and Development/drug effects

KW - Humans

KW - Male

KW - Sulfonic Acids

KW - Time

U2 - 10.1016/j.scitotenv.2018.02.050

DO - 10.1016/j.scitotenv.2018.02.050

M3 - Journal article

C2 - 29438932

VL - 628-629

SP - 226

EP - 232

JO - Science of the Total Environment

JF - Science of the Total Environment

SN - 0048-9697

ER -

ID: 230068321