TY - JOUR

T1 - Prediction of 7-year psychopathology from mother-infant joint attention behaviours

T2 - a nested case-control study

AU - Allely, Clare S

AU - Johnson, Paul C D

AU - Marwick, Helen

AU - Lidstone, Emma

AU - Kočovská, Eva

AU - Puckering, Christine

AU - McConnachie, Alex

AU - Golding, Jean

AU - Gillberg, Christopher

AU - Wilson, Philip

PY - 2013/9/24

Y1 - 2013/9/24

N2 - BACKGROUND: To investigate whether later diagnosis of psychiatric disorder can be predicted from analysis of mother-infant joint attention (JA) behaviours in social-communicative interaction at 12 months.METHOD: Using data from a large contemporary birth cohort, we examined 159 videos of a mother-infant interaction for joint attention behaviour when children were aged one year, sampled from within the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort. Fifty-three of the videos involved infants who were later considered to have a psychiatric disorder at seven years and 106 were same aged controls. Psychopathologies included in the case group were disruptive behaviour disorders, oppositional-conduct disorder, attention-deficit/hyperactivity disorder, pervasive development disorder, anxiety and depressive disorders. Psychiatric diagnoses were obtained using the Development and Wellbeing Assessment when the children were seven years old.RESULTS: None of the three JA behaviours (shared look rate, shared attention rate and shared attention intensity) showed a significant association with the primary outcome of case-control status. Only shared look rate predicted any of the exploratory sub-diagnosis outcomes and was found to be positively associated with later oppositional-conduct disorders (OR [95% CI]: 1.5 [1.0, 2.3]; p = 0.041).CONCLUSIONS: JA behaviours did not, in general, predict later psychopathology. However, shared look was positively associated with later oppositional-conduct disorders. This suggests that some features of JA may be early markers of later psychopathology. Further investigation will be required to determine whether any JA behaviours can be used to screen for families in need of intervention.

AB - BACKGROUND: To investigate whether later diagnosis of psychiatric disorder can be predicted from analysis of mother-infant joint attention (JA) behaviours in social-communicative interaction at 12 months.METHOD: Using data from a large contemporary birth cohort, we examined 159 videos of a mother-infant interaction for joint attention behaviour when children were aged one year, sampled from within the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort. Fifty-three of the videos involved infants who were later considered to have a psychiatric disorder at seven years and 106 were same aged controls. Psychopathologies included in the case group were disruptive behaviour disorders, oppositional-conduct disorder, attention-deficit/hyperactivity disorder, pervasive development disorder, anxiety and depressive disorders. Psychiatric diagnoses were obtained using the Development and Wellbeing Assessment when the children were seven years old.RESULTS: None of the three JA behaviours (shared look rate, shared attention rate and shared attention intensity) showed a significant association with the primary outcome of case-control status. Only shared look rate predicted any of the exploratory sub-diagnosis outcomes and was found to be positively associated with later oppositional-conduct disorders (OR [95% CI]: 1.5 [1.0, 2.3]; p = 0.041).CONCLUSIONS: JA behaviours did not, in general, predict later psychopathology. However, shared look was positively associated with later oppositional-conduct disorders. This suggests that some features of JA may be early markers of later psychopathology. Further investigation will be required to determine whether any JA behaviours can be used to screen for families in need of intervention.

KW - Adult

KW - Attention

KW - Case-Control Studies

KW - Child

KW - Cohort Studies

KW - Depression, Postpartum/diagnosis

KW - Female

KW - Humans

KW - Infant

KW - Longitudinal Studies

KW - Male

KW - Maternal Behavior/psychology

KW - Mental Disorders/diagnosis

KW - Mother-Child Relations/psychology

KW - Odds Ratio

KW - Videotape Recording

U2 - 10.1186/1471-2431-13-147

DO - 10.1186/1471-2431-13-147

M3 - Journal article

C2 - 24063312

VL - 13

SP - 147

JO - BMC Pediatrics

JF - BMC Pediatrics

SN - 1471-2431

ER -