Normal tension glaucoma and Alzheimer disease: comorbidity?
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Normal tension glaucoma and Alzheimer disease : comorbidity? / Bach-Holm, Daniella; Kessing, Svend Vedel; Mogensen, Ulla Brasch; Forman, Julie Lyng; Andersen, Per Kragh; Kessing, Lars Vedel.
I: Acta Ophthalmologica, Bind 89, 2012, s. 1-3.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Normal tension glaucoma and Alzheimer disease
T2 - comorbidity?
AU - Bach-Holm, Daniella
AU - Kessing, Svend Vedel
AU - Mogensen, Ulla Brasch
AU - Forman, Julie Lyng
AU - Andersen, Per Kragh
AU - Kessing, Lars Vedel
N1 - © 2011 The Authors. Acta Ophthalmologica © 2011 Acta Ophthalmologica Scandinavica Foundation.
PY - 2012
Y1 - 2012
N2 - Purpose: To investigate whether normal tension glaucoma (NTG) is associated with increased risk of developing dementia/Alzheimer disease (AD). Methods: A total of 69 patients with NTG were identified in the case note files in the Glaucoma Clinic, University Hospital of Copenhagen (Rigshospitalet), Denmark from 1980 to 2001. The rate of a subsequent diagnosis of dementia as recorded in nationwide health care registers from 1980 to 2005 was estimated and compared with the rate for the general population [standard mortality rate (SMR) = observed number of cases of dementia/expected number of cases of dementia]. Results: The 69 patients had a median age of 64 years (quartiles 57 and 73) at the time of the diagnosis, and the average follow-up period was 12.7 years. The SMR(dementia) was 0.20 (95% CI 0.01-1.11). No patient developed AD. Conclusion: Normal tension glaucoma was not associated with an increased risk of developing dementia/AD.
AB - Purpose: To investigate whether normal tension glaucoma (NTG) is associated with increased risk of developing dementia/Alzheimer disease (AD). Methods: A total of 69 patients with NTG were identified in the case note files in the Glaucoma Clinic, University Hospital of Copenhagen (Rigshospitalet), Denmark from 1980 to 2001. The rate of a subsequent diagnosis of dementia as recorded in nationwide health care registers from 1980 to 2005 was estimated and compared with the rate for the general population [standard mortality rate (SMR) = observed number of cases of dementia/expected number of cases of dementia]. Results: The 69 patients had a median age of 64 years (quartiles 57 and 73) at the time of the diagnosis, and the average follow-up period was 12.7 years. The SMR(dementia) was 0.20 (95% CI 0.01-1.11). No patient developed AD. Conclusion: Normal tension glaucoma was not associated with an increased risk of developing dementia/AD.
U2 - 10.1111/j.1755-3768.2011.02125.x
DO - 10.1111/j.1755-3768.2011.02125.x
M3 - Journal article
C2 - 21332678
VL - 89
SP - 1
EP - 3
JO - Acta Ophthalmologica
JF - Acta Ophthalmologica
SN - 1755-375X
ER -
ID: 40169814