Joint effect of alcohol consumption and educational level on alcohol-related medical events: A Danish register-based cohort study

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Joint effect of alcohol consumption and educational level on alcohol-related medical events : A Danish register-based cohort study. / Nordahl Christensen, Helene; Diderichsen, Finn; Hvidtfeldt, Ulla Arthur; Lange, Theis; Andersen, Per Kragh; Osler, Merete; Prescott, Eva; Tjønneland, Anne; Rod, Naja Hulvej; Andersen, Ingelise.

I: Epidemiology, Bind 28, Nr. 6, 11.2017, s. 872–879.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Nordahl Christensen, H, Diderichsen, F, Hvidtfeldt, UA, Lange, T, Andersen, PK, Osler, M, Prescott, E, Tjønneland, A, Rod, NH & Andersen, I 2017, 'Joint effect of alcohol consumption and educational level on alcohol-related medical events: A Danish register-based cohort study', Epidemiology, bind 28, nr. 6, s. 872–879. https://doi.org/10.1097/EDE.0000000000000718

APA

Nordahl Christensen, H., Diderichsen, F., Hvidtfeldt, U. A., Lange, T., Andersen, P. K., Osler, M., ... Andersen, I. (2017). Joint effect of alcohol consumption and educational level on alcohol-related medical events: A Danish register-based cohort study. Epidemiology, 28(6), 872–879. https://doi.org/10.1097/EDE.0000000000000718

Vancouver

Nordahl Christensen H, Diderichsen F, Hvidtfeldt UA, Lange T, Andersen PK, Osler M o.a. Joint effect of alcohol consumption and educational level on alcohol-related medical events: A Danish register-based cohort study. Epidemiology. 2017 nov;28(6):872–879. https://doi.org/10.1097/EDE.0000000000000718

Author

Nordahl Christensen, Helene ; Diderichsen, Finn ; Hvidtfeldt, Ulla Arthur ; Lange, Theis ; Andersen, Per Kragh ; Osler, Merete ; Prescott, Eva ; Tjønneland, Anne ; Rod, Naja Hulvej ; Andersen, Ingelise. / Joint effect of alcohol consumption and educational level on alcohol-related medical events : A Danish register-based cohort study. I: Epidemiology. 2017 ; Bind 28, Nr. 6. s. 872–879.

Bibtex

@article{50378598037d449da096ab917f0b484e,
title = "Joint effect of alcohol consumption and educational level on alcohol-related medical events: A Danish register-based cohort study",
abstract = "Background: Alcohol-related mortality is more pronounced in lower than in higher socioeconomic groups in Western countries. Part of the explanation is differences in drinking patterns. However, differences in vulnerability to health consequences of alcohol consumption across socioeconomic groups may also play a role. We investigated the joint effect of alcohol consumption and educational level on the rate of alcohol-related medical events.Methods: We pooled seven prospective cohorts from Denmark that enrolled 74,278 men and women age 30–70 years (study period, 1981 to 2009). We measured alcohol consumption at baseline using self-administrated questionnaires. Information on highest attained education 1 year before study entry and hospital and mortality data on alcohol-related medical events were obtained through linkage to nationwide registries. We performed analyses using the Aalen additive hazards model.Results: During follow-up (1,085,049 person-years), a total of 1718 alcohol-related events occurred. The joint effect of very high alcohol consumption (>21 [>28] drinks per week in women [men]) and low education on alcohol-related events exceeded the sum of their separate effects. Among men, we observed 289 (95{\%} confidence interval = 123, 457) extra events per 100,000 person-years owing to education–alcohol interaction (P < 0.001). Similarly, among women, we observed 239 (95{\%} confidence interval = 90, 388) extra events per 100,000 person-years owing to this interaction (P < 0.001).Conclusions: High alcohol consumption is associated with a higher risk of alcohol-related medical events among those with low compared with high education. This interaction may be explained by differences in vulnerability and drinking patterns across educational groups.See video abstract at, http://links.lww.com/EDE/B267",
author = "{Nordahl Christensen}, Helene and Finn Diderichsen and Hvidtfeldt, {Ulla Arthur} and Theis Lange and Andersen, {Per Kragh} and Merete Osler and Eva Prescott and Anne Tj{\o}nneland and Rod, {Naja Hulvej} and Ingelise Andersen",
year = "2017",
month = "11",
doi = "10.1097/EDE.0000000000000718",
language = "English",
volume = "28",
pages = "872–879",
journal = "Epidemiology",
issn = "1044-3983",
publisher = "Lippincott Williams & Wilkins",
number = "6",

}

RIS

TY - JOUR

T1 - Joint effect of alcohol consumption and educational level on alcohol-related medical events

T2 - A Danish register-based cohort study

AU - Nordahl Christensen, Helene

AU - Diderichsen, Finn

AU - Hvidtfeldt, Ulla Arthur

AU - Lange, Theis

AU - Andersen, Per Kragh

AU - Osler, Merete

AU - Prescott, Eva

AU - Tjønneland, Anne

AU - Rod, Naja Hulvej

AU - Andersen, Ingelise

PY - 2017/11

Y1 - 2017/11

N2 - Background: Alcohol-related mortality is more pronounced in lower than in higher socioeconomic groups in Western countries. Part of the explanation is differences in drinking patterns. However, differences in vulnerability to health consequences of alcohol consumption across socioeconomic groups may also play a role. We investigated the joint effect of alcohol consumption and educational level on the rate of alcohol-related medical events.Methods: We pooled seven prospective cohorts from Denmark that enrolled 74,278 men and women age 30–70 years (study period, 1981 to 2009). We measured alcohol consumption at baseline using self-administrated questionnaires. Information on highest attained education 1 year before study entry and hospital and mortality data on alcohol-related medical events were obtained through linkage to nationwide registries. We performed analyses using the Aalen additive hazards model.Results: During follow-up (1,085,049 person-years), a total of 1718 alcohol-related events occurred. The joint effect of very high alcohol consumption (>21 [>28] drinks per week in women [men]) and low education on alcohol-related events exceeded the sum of their separate effects. Among men, we observed 289 (95% confidence interval = 123, 457) extra events per 100,000 person-years owing to education–alcohol interaction (P < 0.001). Similarly, among women, we observed 239 (95% confidence interval = 90, 388) extra events per 100,000 person-years owing to this interaction (P < 0.001).Conclusions: High alcohol consumption is associated with a higher risk of alcohol-related medical events among those with low compared with high education. This interaction may be explained by differences in vulnerability and drinking patterns across educational groups.See video abstract at, http://links.lww.com/EDE/B267

AB - Background: Alcohol-related mortality is more pronounced in lower than in higher socioeconomic groups in Western countries. Part of the explanation is differences in drinking patterns. However, differences in vulnerability to health consequences of alcohol consumption across socioeconomic groups may also play a role. We investigated the joint effect of alcohol consumption and educational level on the rate of alcohol-related medical events.Methods: We pooled seven prospective cohorts from Denmark that enrolled 74,278 men and women age 30–70 years (study period, 1981 to 2009). We measured alcohol consumption at baseline using self-administrated questionnaires. Information on highest attained education 1 year before study entry and hospital and mortality data on alcohol-related medical events were obtained through linkage to nationwide registries. We performed analyses using the Aalen additive hazards model.Results: During follow-up (1,085,049 person-years), a total of 1718 alcohol-related events occurred. The joint effect of very high alcohol consumption (>21 [>28] drinks per week in women [men]) and low education on alcohol-related events exceeded the sum of their separate effects. Among men, we observed 289 (95% confidence interval = 123, 457) extra events per 100,000 person-years owing to education–alcohol interaction (P < 0.001). Similarly, among women, we observed 239 (95% confidence interval = 90, 388) extra events per 100,000 person-years owing to this interaction (P < 0.001).Conclusions: High alcohol consumption is associated with a higher risk of alcohol-related medical events among those with low compared with high education. This interaction may be explained by differences in vulnerability and drinking patterns across educational groups.See video abstract at, http://links.lww.com/EDE/B267

U2 - 10.1097/EDE.0000000000000718

DO - 10.1097/EDE.0000000000000718

M3 - Journal article

C2 - 28731961

VL - 28

SP - 872

EP - 879

JO - Epidemiology

JF - Epidemiology

SN - 1044-3983

IS - 6

ER -

ID: 182979574