Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Standard

Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial. / Zwisler, Ann-Dorthe Olsen; Soja, Anne Merete Boas; Rasmussen, Søren; Frederiksen, Marianne; Abadini, Sadollah; Appel, Jon; Rasmussen, Hanne; Gluud, Christian; Iversen, Lars; Sigurd, Bjarne; Madsen, Mette; Fischer-Hansen, Jørgen; DANREHAB Group.

I: American Heart Journal, Bind 155, Nr. 6, 2008, s. 1106-13.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Zwisler, A-DO, Soja, AMB, Rasmussen, S, Frederiksen, M, Abadini, S, Appel, J, Rasmussen, H, Gluud, C, Iversen, L, Sigurd, B, Madsen, M, Fischer-Hansen, J & DANREHAB Group 2008, 'Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial.', American Heart Journal, bind 155, nr. 6, s. 1106-13. https://doi.org/10.1016/j.ahj.2007.12.033

APA

Zwisler, A-D. O., Soja, A. M. B., Rasmussen, S., Frederiksen, M., Abadini, S., Appel, J., Rasmussen, H., Gluud, C., Iversen, L., Sigurd, B., Madsen, M., Fischer-Hansen, J., & DANREHAB Group (2008). Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial. American Heart Journal, 155(6), 1106-13. https://doi.org/10.1016/j.ahj.2007.12.033

Vancouver

Zwisler A-DO, Soja AMB, Rasmussen S, Frederiksen M, Abadini S, Appel J o.a. Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial. American Heart Journal. 2008;155(6):1106-13. https://doi.org/10.1016/j.ahj.2007.12.033

Author

Zwisler, Ann-Dorthe Olsen ; Soja, Anne Merete Boas ; Rasmussen, Søren ; Frederiksen, Marianne ; Abadini, Sadollah ; Appel, Jon ; Rasmussen, Hanne ; Gluud, Christian ; Iversen, Lars ; Sigurd, Bjarne ; Madsen, Mette ; Fischer-Hansen, Jørgen ; DANREHAB Group. / Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial. I: American Heart Journal. 2008 ; Bind 155, Nr. 6. s. 1106-13.

Bibtex

@article{dbb715b045e111ddb7b4000ea68e967b,
title = "Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial.",
abstract = "BACKGROUND: Current guidelines broadly recommend comprehensive cardiac rehabilitation (CCR), although evidence for this is still limited. We investigated the 12-month effect of hospital-based CCR versus usual care (UC) for a broadly defined group of cardiac patients within the modern therapeutic era of cardiology. METHODS: We conducted a centrally randomized single-center clinical trial with blinded assessment of the primary outcome: registry-based composite of total mortality, myocardial infarction, or acute first-time readmission due to heart disease. Other outcomes were hospitalization, risk profile, and quality of life. The trial included 770 participants (20-94 years) with congestive heart failure (12%), ischemic heart disease (58%), or high risk of ischemic heart disease (30%). Comprehensive cardiac rehabilitation is composed of 6 weeks of intensive intervention and systematic follow-up for 10.5 months. RESULTS: We randomized 380 patients to CCR versus 390 to UC. Randomization was well balanced. The primary outcome occurred in 31% of both groups (relative risk 0.96, 95% confidence interval 0.78-1.26). Compared with the UC group, CCR significantly reduced length of stay by 15% (95% confidence interval 1.1%-27.1%, P = .04), mean number of cardiac risk factors above target (4.5 vs 4.1, P = .01), patients with systolic blood pressure below target (P = .003), physically inactivity (P = .01), and unhealthy dietary habits (P = .0003). Short-Form-36 and Hospital Anxiety and Depression Scale did not differ significantly. CONCLUSION: At 12 months, the CCR and UC groups did not differ regarding the primary composite outcome. Comprehensive cardiac rehabilitation significantly reduced length of hospital stay and improved cardiac risk factors.",
author = "Zwisler, {Ann-Dorthe Olsen} and Soja, {Anne Merete Boas} and S{\o}ren Rasmussen and Marianne Frederiksen and Sadollah Abadini and Jon Appel and Hanne Rasmussen and Christian Gluud and Lars Iversen and Bjarne Sigurd and Mette Madsen and J{\o}rgen Fischer-Hansen and {DANREHAB Group}",
note = "Keywords: Adult; Aged; Aged, 80 and over; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Myocardial Ischemia; Risk Factors; Severity of Illness Index",
year = "2008",
doi = "10.1016/j.ahj.2007.12.033",
language = "English",
volume = "155",
pages = "1106--13",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
number = "6",

}

RIS

TY - JOUR

T1 - Hospital-based comprehensive cardiac rehabilitation versus usual care among patients with congestive heart failure, ischemic heart disease, or high risk of ischemic heart disease: 12-month results of a randomized clinical trial.

AU - Zwisler, Ann-Dorthe Olsen

AU - Soja, Anne Merete Boas

AU - Rasmussen, Søren

AU - Frederiksen, Marianne

AU - Abadini, Sadollah

AU - Appel, Jon

AU - Rasmussen, Hanne

AU - Gluud, Christian

AU - Iversen, Lars

AU - Sigurd, Bjarne

AU - Madsen, Mette

AU - Fischer-Hansen, Jørgen

AU - DANREHAB Group

N1 - Keywords: Adult; Aged; Aged, 80 and over; Female; Heart Failure; Hospitalization; Humans; Male; Middle Aged; Myocardial Ischemia; Risk Factors; Severity of Illness Index

PY - 2008

Y1 - 2008

N2 - BACKGROUND: Current guidelines broadly recommend comprehensive cardiac rehabilitation (CCR), although evidence for this is still limited. We investigated the 12-month effect of hospital-based CCR versus usual care (UC) for a broadly defined group of cardiac patients within the modern therapeutic era of cardiology. METHODS: We conducted a centrally randomized single-center clinical trial with blinded assessment of the primary outcome: registry-based composite of total mortality, myocardial infarction, or acute first-time readmission due to heart disease. Other outcomes were hospitalization, risk profile, and quality of life. The trial included 770 participants (20-94 years) with congestive heart failure (12%), ischemic heart disease (58%), or high risk of ischemic heart disease (30%). Comprehensive cardiac rehabilitation is composed of 6 weeks of intensive intervention and systematic follow-up for 10.5 months. RESULTS: We randomized 380 patients to CCR versus 390 to UC. Randomization was well balanced. The primary outcome occurred in 31% of both groups (relative risk 0.96, 95% confidence interval 0.78-1.26). Compared with the UC group, CCR significantly reduced length of stay by 15% (95% confidence interval 1.1%-27.1%, P = .04), mean number of cardiac risk factors above target (4.5 vs 4.1, P = .01), patients with systolic blood pressure below target (P = .003), physically inactivity (P = .01), and unhealthy dietary habits (P = .0003). Short-Form-36 and Hospital Anxiety and Depression Scale did not differ significantly. CONCLUSION: At 12 months, the CCR and UC groups did not differ regarding the primary composite outcome. Comprehensive cardiac rehabilitation significantly reduced length of hospital stay and improved cardiac risk factors.

AB - BACKGROUND: Current guidelines broadly recommend comprehensive cardiac rehabilitation (CCR), although evidence for this is still limited. We investigated the 12-month effect of hospital-based CCR versus usual care (UC) for a broadly defined group of cardiac patients within the modern therapeutic era of cardiology. METHODS: We conducted a centrally randomized single-center clinical trial with blinded assessment of the primary outcome: registry-based composite of total mortality, myocardial infarction, or acute first-time readmission due to heart disease. Other outcomes were hospitalization, risk profile, and quality of life. The trial included 770 participants (20-94 years) with congestive heart failure (12%), ischemic heart disease (58%), or high risk of ischemic heart disease (30%). Comprehensive cardiac rehabilitation is composed of 6 weeks of intensive intervention and systematic follow-up for 10.5 months. RESULTS: We randomized 380 patients to CCR versus 390 to UC. Randomization was well balanced. The primary outcome occurred in 31% of both groups (relative risk 0.96, 95% confidence interval 0.78-1.26). Compared with the UC group, CCR significantly reduced length of stay by 15% (95% confidence interval 1.1%-27.1%, P = .04), mean number of cardiac risk factors above target (4.5 vs 4.1, P = .01), patients with systolic blood pressure below target (P = .003), physically inactivity (P = .01), and unhealthy dietary habits (P = .0003). Short-Form-36 and Hospital Anxiety and Depression Scale did not differ significantly. CONCLUSION: At 12 months, the CCR and UC groups did not differ regarding the primary composite outcome. Comprehensive cardiac rehabilitation significantly reduced length of hospital stay and improved cardiac risk factors.

U2 - 10.1016/j.ahj.2007.12.033

DO - 10.1016/j.ahj.2007.12.033

M3 - Journal article

C2 - 18513526

VL - 155

SP - 1106

EP - 1113

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 6

ER -

ID: 4818263