Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage
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Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage. / Nielsen, H S; Steffensen, R; Lund, M; Egestad, L; Mortensen, L H; Andersen, Anne-Marie Nybo; Lidegaard, Ø; Christiansen, O B.
I: Human Reproduction, Bind 25, Nr. 6, 06.2010, s. 1543-52.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › fagfællebedømt
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TY - JOUR
T1 - Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage
AU - Nielsen, H S
AU - Steffensen, R
AU - Lund, M
AU - Egestad, L
AU - Mortensen, L H
AU - Andersen, Anne-Marie Nybo
AU - Lidegaard, Ø
AU - Christiansen, O B
PY - 2010/6
Y1 - 2010/6
N2 - The chance of a live birth after a diagnosis of secondary recurrent miscarriage (SRM) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry HLA class II alleles that efficiently present male-specific (H-Y) antigens to the immune system. Information about obstetric complications in births prior and subsequent to the SRM diagnosis is limited. The relations between maternal carriage of H-Y-restricting HLA, fetal sex, obstetric complications and prognosis are unknown.
AB - The chance of a live birth after a diagnosis of secondary recurrent miscarriage (SRM) is reduced in patients who, prior to the miscarriages, gave birth to a boy and carry HLA class II alleles that efficiently present male-specific (H-Y) antigens to the immune system. Information about obstetric complications in births prior and subsequent to the SRM diagnosis is limited. The relations between maternal carriage of H-Y-restricting HLA, fetal sex, obstetric complications and prognosis are unknown.
KW - Abortion, Habitual
KW - Alleles
KW - Denmark
KW - Female
KW - H-Y Antigen
KW - HLA Antigens
KW - Histocompatibility, Maternal-Fetal
KW - Humans
KW - Infant, Newborn
KW - Live Birth
KW - Male
KW - Pregnancy
KW - Pregnancy Complications
KW - Registries
KW - Risk Factors
KW - Statistics, Nonparametric
U2 - 10.1093/humrep/deq091
DO - 10.1093/humrep/deq091
M3 - Journal article
C2 - 20395221
VL - 25
SP - 1543
EP - 1552
JO - Human Reproduction
JF - Human Reproduction
SN - 0268-1161
IS - 6
ER -
ID: 32325789