Feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients undergoing chemotherapy
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Feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients undergoing chemotherapy. / Adamsen, Lis; Midtgaard, Julie; Rorth, Mikael; Borregaard, Niels; Andersen, Christina; Quist, Morten; Møller, Tom; Zacho, Morten; Madsen, Jan K; Knutsen, Lasse.
I: Supportive Care in Cancer, Bind 11, Nr. 11, 11.2003, s. 707-16.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients undergoing chemotherapy
AU - Adamsen, Lis
AU - Midtgaard, Julie
AU - Rorth, Mikael
AU - Borregaard, Niels
AU - Andersen, Christina
AU - Quist, Morten
AU - Møller, Tom
AU - Zacho, Morten
AU - Madsen, Jan K
AU - Knutsen, Lasse
PY - 2003/11
Y1 - 2003/11
N2 - Cancer patients frequently experience considerable loss of physical capacity and general wellbeing when diagnosed and treated for their disease. The aim of this study was to evaluate the feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients during advanced stages of disease who are undergoing adjuvant or high-dose chemotherapy. The supervised program included high- and low-intensity activities (physical exercise, relaxation, massage, and body-awareness training). A total of 23 patients between 18 and 65 years of age (median 40 years) participated in groups of seven to nine patients for 9 h weekly for 6 weeks. Physical capacity in terms of repetition maximum (RM) and maximal oxygen uptake (VO(2)max), physical activity level and psychosocial wellbeing (EORTC QLQ-C30, SF-36, HAD) were compared prior to and after completion of the program. The program was safe and well tolerated. The completion rate was 85.2%. Highly significant increases in physical capacity (1RM, VO(2)max) and an improved level of physical activity were achieved. Quality of life and general wellbeing assessments indicated improvements in several measures, but without reaching significance. It is concluded that an exercise program, which combines high- and low-intensity physical activities, may be used to prevent and/or minimize physical inactivity, fatigue, muscle wasting and energy loss in cancer patients undergoing chemotherapy.
AB - Cancer patients frequently experience considerable loss of physical capacity and general wellbeing when diagnosed and treated for their disease. The aim of this study was to evaluate the feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients during advanced stages of disease who are undergoing adjuvant or high-dose chemotherapy. The supervised program included high- and low-intensity activities (physical exercise, relaxation, massage, and body-awareness training). A total of 23 patients between 18 and 65 years of age (median 40 years) participated in groups of seven to nine patients for 9 h weekly for 6 weeks. Physical capacity in terms of repetition maximum (RM) and maximal oxygen uptake (VO(2)max), physical activity level and psychosocial wellbeing (EORTC QLQ-C30, SF-36, HAD) were compared prior to and after completion of the program. The program was safe and well tolerated. The completion rate was 85.2%. Highly significant increases in physical capacity (1RM, VO(2)max) and an improved level of physical activity were achieved. Quality of life and general wellbeing assessments indicated improvements in several measures, but without reaching significance. It is concluded that an exercise program, which combines high- and low-intensity physical activities, may be used to prevent and/or minimize physical inactivity, fatigue, muscle wasting and energy loss in cancer patients undergoing chemotherapy.
KW - Activities of Daily Living
KW - Adaptation, Psychological
KW - Adult
KW - Aged
KW - Chemotherapy, Adjuvant
KW - Combined Modality Therapy
KW - Exercise Therapy
KW - Exercise Tolerance
KW - Feasibility Studies
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Neoplasms
KW - Oxygen Consumption
KW - Physical Fitness
KW - Quality of Life
KW - Sickness Impact Profile
KW - Surveys and Questionnaires
KW - Time Factors
KW - Journal Article
KW - Research Support, Non-U.S. Gov't
U2 - 10.1007/s00520-003-0504-2
DO - 10.1007/s00520-003-0504-2
M3 - Journal article
C2 - 12898370
VL - 11
SP - 707
EP - 716
JO - Supportive Care in Cancer
JF - Supportive Care in Cancer
SN - 0941-4355
IS - 11
ER -
ID: 179127778