Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis

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Standard

Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis. / Knudsen, K. B.; Pressler, T.; Mortensen, L. H.; Jarden, M.; Skov, M.; Quittner, A. L.; Katzenstein, T.; Boisen, K.A.

I: SpringerPlus, Bind 5, 1216, 2016.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Knudsen, KB, Pressler, T, Mortensen, LH, Jarden, M, Skov, M, Quittner, AL, Katzenstein, T & Boisen, KA 2016, 'Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis', SpringerPlus, bind 5, 1216. https://doi.org/10.1186/s40064-016-2862-5

APA

Knudsen, K. B., Pressler, T., Mortensen, L. H., Jarden, M., Skov, M., Quittner, A. L., ... Boisen, K. A. (2016). Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis. SpringerPlus, 5, [1216]. https://doi.org/10.1186/s40064-016-2862-5

Vancouver

Knudsen KB, Pressler T, Mortensen LH, Jarden M, Skov M, Quittner AL o.a. Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis. SpringerPlus. 2016;5. 1216. https://doi.org/10.1186/s40064-016-2862-5

Author

Knudsen, K. B. ; Pressler, T. ; Mortensen, L. H. ; Jarden, M. ; Skov, M. ; Quittner, A. L. ; Katzenstein, T. ; Boisen, K.A. / Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis. I: SpringerPlus. 2016 ; Bind 5.

Bibtex

@article{be5986a38a7d47dba19c2c7cf4438fe8,
title = "Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis",
abstract = "Background: Cystic fibrosis (CF) is a life shortening disease, however prognosis has improved and the adult population is growing. Most adults with cystic fibrosis live independent lives and balance the demands of work and family life with a significant treatment burden. The aim of this study was to examine the relationships among treatment adherence, symptoms of depression and health-related quality of life (HRQoL) in a population of young adults with CF.Methods: We administered three standardized questionnaires to 67 patients with CF aged 18–30 years; Morisky Medication Adherence Scale, Major Depression Inventory, and Cystic Fibrosis Questionnaire-Revised.Results: There was a response rate of 77 {\%} and a majority of the young adults (84 {\%}) were employed or in an education program. Most participants (74 {\%}) reported low adherence to medications. One third (32.8 {\%}) of the participants reported symptoms of depression. HRQoL scores were especially low on Vitality and Treatment Burden, and symptoms of depression were associated with low HRQoL scores (p < 0.01) with medium to large deficits across on all HRQoL domains (Cohen’s d 0.60–1.72) except for the domain treatment burden. High depression symptom scores were associated with low adherence (r = −0.412, p < 0.001).Conclusions: Despite improved physical health, many patients with CF report poor adherence, as well as impaired mental wellbeing and HRQoL. Thus, more attention to mental health issues is needed.",
keywords = "Cystic fibrosis, Adherence, Depression, Quality of life, Mental health, Young adults",
author = "Knudsen, {K. B.} and T. Pressler and Mortensen, {L. H.} and M. Jarden and M. Skov and Quittner, {A. L.} and T. Katzenstein and K.A. Boisen",
note = "Erratum to: Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis. DOI: 10.1186/s40064-017-3789-1",
year = "2016",
doi = "10.1186/s40064-016-2862-5",
language = "English",
volume = "5",
journal = "SpringerPlus",
issn = "2193-1801",
publisher = "SpringerOpen",

}

RIS

TY - JOUR

T1 - Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis

AU - Knudsen, K. B.

AU - Pressler, T.

AU - Mortensen, L. H.

AU - Jarden, M.

AU - Skov, M.

AU - Quittner, A. L.

AU - Katzenstein, T.

AU - Boisen, K.A.

N1 - Erratum to: Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis. DOI: 10.1186/s40064-017-3789-1

PY - 2016

Y1 - 2016

N2 - Background: Cystic fibrosis (CF) is a life shortening disease, however prognosis has improved and the adult population is growing. Most adults with cystic fibrosis live independent lives and balance the demands of work and family life with a significant treatment burden. The aim of this study was to examine the relationships among treatment adherence, symptoms of depression and health-related quality of life (HRQoL) in a population of young adults with CF.Methods: We administered three standardized questionnaires to 67 patients with CF aged 18–30 years; Morisky Medication Adherence Scale, Major Depression Inventory, and Cystic Fibrosis Questionnaire-Revised.Results: There was a response rate of 77 % and a majority of the young adults (84 %) were employed or in an education program. Most participants (74 %) reported low adherence to medications. One third (32.8 %) of the participants reported symptoms of depression. HRQoL scores were especially low on Vitality and Treatment Burden, and symptoms of depression were associated with low HRQoL scores (p < 0.01) with medium to large deficits across on all HRQoL domains (Cohen’s d 0.60–1.72) except for the domain treatment burden. High depression symptom scores were associated with low adherence (r = −0.412, p < 0.001).Conclusions: Despite improved physical health, many patients with CF report poor adherence, as well as impaired mental wellbeing and HRQoL. Thus, more attention to mental health issues is needed.

AB - Background: Cystic fibrosis (CF) is a life shortening disease, however prognosis has improved and the adult population is growing. Most adults with cystic fibrosis live independent lives and balance the demands of work and family life with a significant treatment burden. The aim of this study was to examine the relationships among treatment adherence, symptoms of depression and health-related quality of life (HRQoL) in a population of young adults with CF.Methods: We administered three standardized questionnaires to 67 patients with CF aged 18–30 years; Morisky Medication Adherence Scale, Major Depression Inventory, and Cystic Fibrosis Questionnaire-Revised.Results: There was a response rate of 77 % and a majority of the young adults (84 %) were employed or in an education program. Most participants (74 %) reported low adherence to medications. One third (32.8 %) of the participants reported symptoms of depression. HRQoL scores were especially low on Vitality and Treatment Burden, and symptoms of depression were associated with low HRQoL scores (p < 0.01) with medium to large deficits across on all HRQoL domains (Cohen’s d 0.60–1.72) except for the domain treatment burden. High depression symptom scores were associated with low adherence (r = −0.412, p < 0.001).Conclusions: Despite improved physical health, many patients with CF report poor adherence, as well as impaired mental wellbeing and HRQoL. Thus, more attention to mental health issues is needed.

KW - Cystic fibrosis

KW - Adherence

KW - Depression

KW - Quality of life

KW - Mental health

KW - Young adults

U2 - 10.1186/s40064-016-2862-5

DO - 10.1186/s40064-016-2862-5

M3 - Journal article

C2 - 27516954

VL - 5

JO - SpringerPlus

JF - SpringerPlus

SN - 2193-1801

M1 - 1216

ER -

ID: 165577416