Association between ambient particulate matter and disorders of vestibular function

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Association between ambient particulate matter and disorders of vestibular function. / Han, Changwoo; Lim, Youn-Hee; Jung, Kweon; Hong, Yun-Chul.

I: Environmental Research, Bind 155, 2017, s. 242-248.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Han, C, Lim, Y-H, Jung, K & Hong, Y-C 2017, 'Association between ambient particulate matter and disorders of vestibular function', Environmental Research, bind 155, s. 242-248. https://doi.org/10.1016/j.envres.2017.02.013

APA

Han, C., Lim, Y-H., Jung, K., & Hong, Y-C. (2017). Association between ambient particulate matter and disorders of vestibular function. Environmental Research, 155, 242-248. https://doi.org/10.1016/j.envres.2017.02.013

Vancouver

Han C, Lim Y-H, Jung K, Hong Y-C. Association between ambient particulate matter and disorders of vestibular function. Environmental Research. 2017;155:242-248. https://doi.org/10.1016/j.envres.2017.02.013

Author

Han, Changwoo ; Lim, Youn-Hee ; Jung, Kweon ; Hong, Yun-Chul. / Association between ambient particulate matter and disorders of vestibular function. I: Environmental Research. 2017 ; Bind 155. s. 242-248.

Bibtex

@article{9509d406436b42aca33b3a1eb08377c6,
title = "Association between ambient particulate matter and disorders of vestibular function",
abstract = "BACKGROUND: Exposure to environmental chemicals has been suggested to alter the physiologic state of the inner and middle ear. However, it is unknown if particulate matter exposure is associated with acute vestibular dysfunction.OBJECTIVES: To estimate the effects of particulate matter exposure on the number of hospital visits related to three major diseases of vestibular dysfunction, Meniere's disease (MD), benign paroxysmal positional vertigo (BPPV), and vestibular neuronitis (VN).METHODS: Our study subject is from Korean National Health Insurance Service-National Sample Cohort, which is dynamic cohort consist of 1 million participants representing the Korean population. Among total cohort participants, we used the hospital visit data of 210,000 individuals who resided in Seoul from 2007 to 2010. Time series analysis using the Poisson generalized additive model and case-crossover analysis using conditional logistic regression were used to investigate the association between daily particulate matter levels (PM2.5, particulate matter <2.5μg/m3; PM10, particulate matter <10μg/m3; PM10-2.5, PM10- PM2.5) and number of MD, BPPV, and VN hospital visits.RESULTS: Time series analysis showed that an interquartile range (IQR) increase in PM10 and PM10-2.5 on lag day 1 was associated with an increased risk of MD hospital visits [relative risk (RR), 95{\%} confidence interval (CI), PM10: 1.09 (1.02-1.15); PM10-2.5: 1.06 (1.02-1.10)]. In addition, elderly individuals (≥60 years old) showed an increased risk of MD hospital visits after particulate matter exposure when compared to younger individuals. An IQR increase in particulate matter on lag day 1 was associated with a marginally significant increase in VN hospital visits [RR (95{\%}CI), PM2.5: 1.11 (0.98-1.25); PM10: 1.07 (0.99-1.15); PM10-2.5: 1.04 (0.99-1.09)]. However, no association between particulate matter exposure and BPPV hospital visits was noted. Case-crossover analyses showed similar results to the time-series analysis across all three diseases.CONCLUSION: MD hospital visits were associated with ambient particulate matter exposure. Elderly individuals, in particular, were more susceptible to particulate matter exposure than younger individuals.",
keywords = "Air Pollutants/analysis, Benign Paroxysmal Positional Vertigo/epidemiology, Environmental Monitoring, Female, Hospitalization/statistics & numerical data, Humans, Male, Meniere Disease/epidemiology, Middle Aged, Particulate Matter/analysis, Risk, Seoul/epidemiology, Vestibular Neuronitis/epidemiology",
author = "Changwoo Han and Youn-Hee Lim and Kweon Jung and Yun-Chul Hong",
note = "Copyright {\circledC} 2017 Elsevier Inc. All rights reserved.",
year = "2017",
doi = "10.1016/j.envres.2017.02.013",
language = "English",
volume = "155",
pages = "242--248",
journal = "Environmental Research",
issn = "0013-9351",
publisher = "Academic Press",

}

RIS

TY - JOUR

T1 - Association between ambient particulate matter and disorders of vestibular function

AU - Han, Changwoo

AU - Lim, Youn-Hee

AU - Jung, Kweon

AU - Hong, Yun-Chul

N1 - Copyright © 2017 Elsevier Inc. All rights reserved.

PY - 2017

Y1 - 2017

N2 - BACKGROUND: Exposure to environmental chemicals has been suggested to alter the physiologic state of the inner and middle ear. However, it is unknown if particulate matter exposure is associated with acute vestibular dysfunction.OBJECTIVES: To estimate the effects of particulate matter exposure on the number of hospital visits related to three major diseases of vestibular dysfunction, Meniere's disease (MD), benign paroxysmal positional vertigo (BPPV), and vestibular neuronitis (VN).METHODS: Our study subject is from Korean National Health Insurance Service-National Sample Cohort, which is dynamic cohort consist of 1 million participants representing the Korean population. Among total cohort participants, we used the hospital visit data of 210,000 individuals who resided in Seoul from 2007 to 2010. Time series analysis using the Poisson generalized additive model and case-crossover analysis using conditional logistic regression were used to investigate the association between daily particulate matter levels (PM2.5, particulate matter <2.5μg/m3; PM10, particulate matter <10μg/m3; PM10-2.5, PM10- PM2.5) and number of MD, BPPV, and VN hospital visits.RESULTS: Time series analysis showed that an interquartile range (IQR) increase in PM10 and PM10-2.5 on lag day 1 was associated with an increased risk of MD hospital visits [relative risk (RR), 95% confidence interval (CI), PM10: 1.09 (1.02-1.15); PM10-2.5: 1.06 (1.02-1.10)]. In addition, elderly individuals (≥60 years old) showed an increased risk of MD hospital visits after particulate matter exposure when compared to younger individuals. An IQR increase in particulate matter on lag day 1 was associated with a marginally significant increase in VN hospital visits [RR (95%CI), PM2.5: 1.11 (0.98-1.25); PM10: 1.07 (0.99-1.15); PM10-2.5: 1.04 (0.99-1.09)]. However, no association between particulate matter exposure and BPPV hospital visits was noted. Case-crossover analyses showed similar results to the time-series analysis across all three diseases.CONCLUSION: MD hospital visits were associated with ambient particulate matter exposure. Elderly individuals, in particular, were more susceptible to particulate matter exposure than younger individuals.

AB - BACKGROUND: Exposure to environmental chemicals has been suggested to alter the physiologic state of the inner and middle ear. However, it is unknown if particulate matter exposure is associated with acute vestibular dysfunction.OBJECTIVES: To estimate the effects of particulate matter exposure on the number of hospital visits related to three major diseases of vestibular dysfunction, Meniere's disease (MD), benign paroxysmal positional vertigo (BPPV), and vestibular neuronitis (VN).METHODS: Our study subject is from Korean National Health Insurance Service-National Sample Cohort, which is dynamic cohort consist of 1 million participants representing the Korean population. Among total cohort participants, we used the hospital visit data of 210,000 individuals who resided in Seoul from 2007 to 2010. Time series analysis using the Poisson generalized additive model and case-crossover analysis using conditional logistic regression were used to investigate the association between daily particulate matter levels (PM2.5, particulate matter <2.5μg/m3; PM10, particulate matter <10μg/m3; PM10-2.5, PM10- PM2.5) and number of MD, BPPV, and VN hospital visits.RESULTS: Time series analysis showed that an interquartile range (IQR) increase in PM10 and PM10-2.5 on lag day 1 was associated with an increased risk of MD hospital visits [relative risk (RR), 95% confidence interval (CI), PM10: 1.09 (1.02-1.15); PM10-2.5: 1.06 (1.02-1.10)]. In addition, elderly individuals (≥60 years old) showed an increased risk of MD hospital visits after particulate matter exposure when compared to younger individuals. An IQR increase in particulate matter on lag day 1 was associated with a marginally significant increase in VN hospital visits [RR (95%CI), PM2.5: 1.11 (0.98-1.25); PM10: 1.07 (0.99-1.15); PM10-2.5: 1.04 (0.99-1.09)]. However, no association between particulate matter exposure and BPPV hospital visits was noted. Case-crossover analyses showed similar results to the time-series analysis across all three diseases.CONCLUSION: MD hospital visits were associated with ambient particulate matter exposure. Elderly individuals, in particular, were more susceptible to particulate matter exposure than younger individuals.

KW - Air Pollutants/analysis

KW - Benign Paroxysmal Positional Vertigo/epidemiology

KW - Environmental Monitoring

KW - Female

KW - Hospitalization/statistics & numerical data

KW - Humans

KW - Male

KW - Meniere Disease/epidemiology

KW - Middle Aged

KW - Particulate Matter/analysis

KW - Risk

KW - Seoul/epidemiology

KW - Vestibular Neuronitis/epidemiology

U2 - 10.1016/j.envres.2017.02.013

DO - 10.1016/j.envres.2017.02.013

M3 - Journal article

C2 - 28236785

VL - 155

SP - 242

EP - 248

JO - Environmental Research

JF - Environmental Research

SN - 0013-9351

ER -

ID: 230069261