Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer: a nationwide registry-based cohort study

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Standard

Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer : a nationwide registry-based cohort study. / Spangmose, A L; Malchau, S S; Henningsen, A A; Forman, J L; Rasmussen, S; Loft, A; Schmidt, L; Pinborg, A.

I: BJOG: An International Journal of Obstetrics and Gynaecology, Bind 126, Nr. 2, 01.2019, s. 261-269.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Spangmose, AL, Malchau, SS, Henningsen, AA, Forman, JL, Rasmussen, S, Loft, A, Schmidt, L & Pinborg, A 2019, 'Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer: a nationwide registry-based cohort study', BJOG: An International Journal of Obstetrics and Gynaecology, bind 126, nr. 2, s. 261-269. https://doi.org/10.1111/1471-0528.15484

APA

Spangmose, A. L., Malchau, S. S., Henningsen, A. A., Forman, J. L., Rasmussen, S., Loft, A., ... Pinborg, A. (2019). Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer: a nationwide registry-based cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 126(2), 261-269. https://doi.org/10.1111/1471-0528.15484

Vancouver

Spangmose AL, Malchau SS, Henningsen AA, Forman JL, Rasmussen S, Loft A o.a. Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer: a nationwide registry-based cohort study. BJOG: An International Journal of Obstetrics and Gynaecology. 2019 jan;126(2):261-269. https://doi.org/10.1111/1471-0528.15484

Author

Spangmose, A L ; Malchau, S S ; Henningsen, A A ; Forman, J L ; Rasmussen, S ; Loft, A ; Schmidt, L ; Pinborg, A. / Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer : a nationwide registry-based cohort study. I: BJOG: An International Journal of Obstetrics and Gynaecology. 2019 ; Bind 126, Nr. 2. s. 261-269.

Bibtex

@article{a77096bcb2a7411495b46c2fe5f4a49a,
title = "Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer: a nationwide registry-based cohort study",
abstract = "OBJECTIVE: To assess academic performance in singletons aged 15-16 years conceived after frozen embryo transfer (FET) compared with singletons born after fresh embryo transfer (ET) in Danish cohorts born from 1995 to 2001.DESIGN: Danish national registry-based cohort study.SETTING: Danish national registries.POPULATION: All 6495 singletons conceived after assisted reproductive technology (ART) treatment in Denmark from 1995 to 2001 [FET (n) = 423; fresh ET (n) = 6072].METHODS: Mean test scores on a national standardised and international comparable grading-scale. Comparisons of test score were first made in univariate analysis (Model 1) and secondly in a multivariate linear model (Model 2) adjusting for relevant reproductive and socio-demographic covariates such as the occupational and educational level of the parents. Sensitivity analyses on FET-IVF (in vitro fertilisation) versus fresh ET-IVF and FET-ICSI (intracytoplasmic sperm injection) versus fresh ET-ICSI were made. Linear mixed models were used to account for the correlation in test scores of siblings for continuous outcome.MAIN OUTCOME MEASURES: Mean overall test score and test score in Danish, mathematics, English, and physics/chemistry.RESULTS: Crude and adjusted mean test scores were similar for adolescents conceived after FET compared with fresh ET. The crude mean difference was +0.11 (95{\%} CI -0.11; 0.34), and the adjusted mean difference was +0.12 (95{\%} CI -0.09; 0.34).CONCLUSIONS: Adolescents conceived after FET had similar academic performance at 15-16 of years of age compared with children conceived after fresh ET.TWEETABLE ABSTRACT: Using frozen embryos in fertility treatment does not affect school performance in Danish adolescents aged 15-16 years.",
author = "Spangmose, {A L} and Malchau, {S S} and Henningsen, {A A} and Forman, {J L} and S Rasmussen and A Loft and L Schmidt and A Pinborg",
note = "{\circledC} 2018 Royal College of Obstetricians and Gynaecologists.",
year = "2019",
month = "1",
doi = "10.1111/1471-0528.15484",
language = "English",
volume = "126",
pages = "261--269",
journal = "B J O G",
issn = "1470-0328",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - Academic performance in adolescents aged 15-16 years born after frozen embryo transfer compared with fresh embryo transfer

T2 - a nationwide registry-based cohort study

AU - Spangmose, A L

AU - Malchau, S S

AU - Henningsen, A A

AU - Forman, J L

AU - Rasmussen, S

AU - Loft, A

AU - Schmidt, L

AU - Pinborg, A

N1 - © 2018 Royal College of Obstetricians and Gynaecologists.

PY - 2019/1

Y1 - 2019/1

N2 - OBJECTIVE: To assess academic performance in singletons aged 15-16 years conceived after frozen embryo transfer (FET) compared with singletons born after fresh embryo transfer (ET) in Danish cohorts born from 1995 to 2001.DESIGN: Danish national registry-based cohort study.SETTING: Danish national registries.POPULATION: All 6495 singletons conceived after assisted reproductive technology (ART) treatment in Denmark from 1995 to 2001 [FET (n) = 423; fresh ET (n) = 6072].METHODS: Mean test scores on a national standardised and international comparable grading-scale. Comparisons of test score were first made in univariate analysis (Model 1) and secondly in a multivariate linear model (Model 2) adjusting for relevant reproductive and socio-demographic covariates such as the occupational and educational level of the parents. Sensitivity analyses on FET-IVF (in vitro fertilisation) versus fresh ET-IVF and FET-ICSI (intracytoplasmic sperm injection) versus fresh ET-ICSI were made. Linear mixed models were used to account for the correlation in test scores of siblings for continuous outcome.MAIN OUTCOME MEASURES: Mean overall test score and test score in Danish, mathematics, English, and physics/chemistry.RESULTS: Crude and adjusted mean test scores were similar for adolescents conceived after FET compared with fresh ET. The crude mean difference was +0.11 (95% CI -0.11; 0.34), and the adjusted mean difference was +0.12 (95% CI -0.09; 0.34).CONCLUSIONS: Adolescents conceived after FET had similar academic performance at 15-16 of years of age compared with children conceived after fresh ET.TWEETABLE ABSTRACT: Using frozen embryos in fertility treatment does not affect school performance in Danish adolescents aged 15-16 years.

AB - OBJECTIVE: To assess academic performance in singletons aged 15-16 years conceived after frozen embryo transfer (FET) compared with singletons born after fresh embryo transfer (ET) in Danish cohorts born from 1995 to 2001.DESIGN: Danish national registry-based cohort study.SETTING: Danish national registries.POPULATION: All 6495 singletons conceived after assisted reproductive technology (ART) treatment in Denmark from 1995 to 2001 [FET (n) = 423; fresh ET (n) = 6072].METHODS: Mean test scores on a national standardised and international comparable grading-scale. Comparisons of test score were first made in univariate analysis (Model 1) and secondly in a multivariate linear model (Model 2) adjusting for relevant reproductive and socio-demographic covariates such as the occupational and educational level of the parents. Sensitivity analyses on FET-IVF (in vitro fertilisation) versus fresh ET-IVF and FET-ICSI (intracytoplasmic sperm injection) versus fresh ET-ICSI were made. Linear mixed models were used to account for the correlation in test scores of siblings for continuous outcome.MAIN OUTCOME MEASURES: Mean overall test score and test score in Danish, mathematics, English, and physics/chemistry.RESULTS: Crude and adjusted mean test scores were similar for adolescents conceived after FET compared with fresh ET. The crude mean difference was +0.11 (95% CI -0.11; 0.34), and the adjusted mean difference was +0.12 (95% CI -0.09; 0.34).CONCLUSIONS: Adolescents conceived after FET had similar academic performance at 15-16 of years of age compared with children conceived after fresh ET.TWEETABLE ABSTRACT: Using frozen embryos in fertility treatment does not affect school performance in Danish adolescents aged 15-16 years.

U2 - 10.1111/1471-0528.15484

DO - 10.1111/1471-0528.15484

M3 - Journal article

C2 - 30276983

VL - 126

SP - 261

EP - 269

JO - B J O G

JF - B J O G

SN - 1470-0328

IS - 2

ER -

ID: 204305310